Iceland· IS-EU/1/20/1468/003
Kaftrio
A ivacaftor, tezacaftor and elexacaftor product containing tezacaftorum inn,elexacaftorum inn,ivacaftorum inn, registered in Iceland by Vertex Pharmaceuticals (Ireland) Limited. The same ATC class is registered in 14 of our 19 countries.
Checked against Icelandic Medicines Agency (Iceland) on
Informational only — not a medical device.
Where it is registered
Ivacaftor, tezacaftor and elexacaftor is registered in 14 of 19 countries.
Countries holding a registration under ATC R07AX32 (ivacaftor, tezacaftor and elexacaftor), each read from that country’s own register.
- This record: Iceland, from Icelandic Medicines Agency (Iceland)
- 9 of them publish a price we can compare per daily dose
Ivacaftor, tezacaftor and elexacaftor · ATC R07AX32
14 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Spainprice
- Switzerlandprice
- United Kingdom
The record
At a glance
Icelandic Medicines Agency (Iceland)- Active substance
- Tezacaftorum INN,Elexacaftorum INN,Ivacaftorum INN
- Manufacturer
- Vertex Pharmaceuticals (Ireland) Limited
- Country
- Iceland (IS)
- ATC code
- R07AX32
- ATC class
- Ivacaftor, tezacaftor and elexacaftor
- Reimbursed
- Not published by this register
- Source register
- Icelandic Medicines Agency (Iceland)
- Last checked
- September 29, 2026
Packs & prices · 0
No packs listed by the register for this record.
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
14 interactions on record for ivacaftor, tezacaftor and elexacaftor.
Graded by severity as the source publishes them — 14 moderate. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Ivacaftor, tezacaftor and elexacaftor · interactions on record
14 records
- 14 moderate
Most severe, free to view
- RifaximinA07AA11moderate
- EmpagliflozinA10BK03moderate
- RepaglinideA10BX02moderate
- EmpagliflozinA10BX12moderate
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Ivacaftor, tezacaftor and elexacaftor in 12 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- SwedenKaftrio 37,5 mg/25 mg/50 mg Filmdragerad tablettVertex Pharmaceuticals Ireland Ltd
- SwitzerlandTrikafta 100 mg / 50 mg / 75 mg, 150 mg, FilmtablettenVertex Pharmaceuticals (CH) GmbH
- CzechiaKAFTRIOVertex Pharmaceuticals (Ireland) Limited, Dublin
- SpainKAFTRIO 37,5 MG/25 MG/50 MG COMPRIMIDOS RECUBIERTOS CON PELICULAVertex Pharmaceuticals (Ireland) Limited
- FinlandKaftrioVertex Pharmaceuticals (Europe) Limited
- FranceKAFTRIO 37,5 mg/25 mg/50 mg, comprimé pelliculéVERTEX PHARMACEUTICALS (IRELAND)
- United KingdomKaftrio 37.5mg/25mg/50mg tabletsVertex Pharmaceuticals (Europe) Ltd
- IrelandKaftrio 37.5 mg/25 mg/50 mg film-coated tabletsVertex Pharmaceuticals (Ireland) Limited
Authorised across Europe · EMA
The same active substance is authorised in 2 EEA countries. Names it is sold under:
- Liechtenstein · Kaftrio
- Norway · Kaftrio
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Icelandic Medicines Agency (Iceland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/f86e7bf3-c023-4574-8c2d-6fdabb2eccb6 GET /v1/drugs/f86e7bf3-c023-4574-8c2d-6fdabb2eccb6?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Kyrni í skammtapoka",
"source": "lyfjastofnun",
"atc_raw": "R07AX32",
"marketed": false,
"strength": "60 mg/ 40 mg/ 80 mg",
"ma_number": "EU/1/20/1468/003",
"substance": "Tezacaftorum INN,Elexacaftorum INN,Ivacaftorum INN",
"other_info": "Ávísun lyfsins er bundin við barnalækna og sérfræðinga í lungnalækningum.",
"legal_status": "(R Z) Sérfræðingsmerkt (og lyfseðilsskylt)",
"ma_issued_serial": "45252"
}See everything about ivacaftor, tezacaftor and elexacaftor.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.