# Drug Database

> Drug Database is a global pharmaceutical-data API. One REST + GraphQL + MCP surface over 610,367 drugs across 19 jurisdictions (US, EU, CH), aggregated from 30+ public registers and kept fresh by an ingestion "watchtower". Operated from Geneva, Switzerland.

How it works (the facts an integrating agent needs):
- Base URL: https://drug-database.com/api/v1 — REST. GraphQL at POST https://drug-database.com/api/v1/graphql. MCP server: npm @drug-database/mcp-server.
- Auth: Authorization: Bearer dd_live_… on every request. Scopes gate endpoints (drugs:read, interactions:write, atc:read, changes:read, webhooks:write).
- The moat is the ingestion watchtower: schema-validated staging, diff-based change feed, schema-drift alerts within 24h, and a stale-data freeze. Every response carries last_synced_at and schema_state, so freshness is a field, not a guess.
- Keep a local copy fresh with the change feed: GET /api/v1/changes?since=<timestamp> returns created/updated/removed entries; store next_cursor and pass it as the next since. Or register a signed webhook (POST /api/v1/webhooks).
- Live metrics: 610,367 drugs · 27,611 interactions · 554,523 tracked changes · 19 jurisdictions · 30+ public sources.
- Honesty: data is aggregated from public sources (Swissmedic, BAG-SL, AIPS, EPha, oddb, EMA, FDA NDC/DailyMed/RxNorm, BfArM, AIFA, BDPM, CIMA, WHO ATC, …). We are NOT affiliated with or endorsed by any of them. Output is a data service, not clinical advice.

## Capabilities
- [Drug search](https://drug-database.com/capabilities/drug-search): Trigram full-text search across 19 jurisdictions — filter by country and ATC, get back the canonical product with reimbursement, dispensing and freshness metadata. (GET /api/v1/drugs)
- [Interaction checks](https://drug-database.com/capabilities/interactions): Send 2–50 drugs by ATC, ID or market identifier and get every interacting pair back with a graded severity, mechanism and recommendation. (POST /api/v1/interactions/check)
- [ATC classification](https://drug-database.com/capabilities/atc-classification): Resolve any ATC code to its node, full parent chain, multilingual labels and DDD — then descend with /children or list the subtree with /drugs. (GET /api/v1/atc/{code})
- [FHIR Medication](https://drug-database.com/capabilities/fhir-medication): Add ?format=fhir to a drug fetch and get a standards-valid FHIR R4 Medication — codes split correctly between coding[] and identifier[], Swiss fields as typed extensions. (GET /api/v1/drugs/{id}?format=fhir)
- [Code lookup](https://drug-database.com/capabilities/code-lookup): Resolve any market identifier — a scanned barcode, a Swiss Pharmacode, a US NDC — to the canonical drug in one indexed read, with the matched pack alongside. (GET /api/v1/drugs/lookup)
- [Change feed](https://drug-database.com/capabilities/change-feed): Poll GET /changes?since=… for a diff of everything that moved, or register a webhook and get pushed — the watchtower turns 30+ registers into one revalidatable stream. (GET /api/v1/changes?since={ts})
- [Monographs](https://drug-database.com/capabilities/monographs): Fetch the structured professional and patient information for a Swiss product in German, French or Italian — the AIPS monograph, parsed into sections. (GET /api/v1/drugs/{id}/monograph)
- [Pricing & competitors](https://drug-database.com/capabilities/pricing-landscape): Per-country prices plus the full set of products that share an ATC class or substance — the feed behind commercialization-feasibility and market-access work. (GET /api/v1/drugs?atc={code}&country={cc})

## Solutions
- [Switzerland drug API](https://drug-database.com/solutions/switzerland-drug-api): A single REST surface over the Swiss drug market: reimbursement, dispensing category, Pharmacode and ATC, stitched from the authoritative registers.
- [Drug interaction API](https://drug-database.com/solutions/drug-interaction-api): POST a medication list by ATC, ID or identifier and get back N-way interaction pairs with a graded severity, mechanism and recommendation.
- [ATC code API](https://drug-database.com/solutions/atc-code-api): The complete WHO ATC classification as a clean REST tree — node, parent chain, multilingual labels, DDD, plus /children and /drugs traversal.
- [FHIR Medication API](https://drug-database.com/solutions/fhir-medication-api): Add ?format=fhir to a drug fetch and receive a standards-valid FHIR R4 Medication — no mapping layer on your side.
- [Pharmacode lookup](https://drug-database.com/solutions/pharmacode-lookup): Resolve a Swiss Pharmacode to the canonical drug product in one indexed read — with ATC, dispensing, reimbursement, and the GTIN / Swissmedic-No bridge.
- [NDC & barcode lookup](https://drug-database.com/solutions/ndc-barcode-lookup): Scan a barcode, get a drug. Resolve a GTIN/EAN or a US NDC to the canonical product in one indexed read, across every identifier system.

## API endpoints (under https://drug-database.com/api/v1)
- GET /drugs — trigram drug search (q, country, atc, limit).
- GET /drugs/{id} — canonical drug; add ?format=fhir for a FHIR R4 Medication.
- GET /drugs/{id}/monograph — structured Swiss monograph (lang=de|fr|it).
- GET /drugs/lookup — resolve an identifier (system=pharmacode|gtin|ndc11|cip13|pzn|swissmedic_no|ean|dmd_amppid, code=…).
- POST /interactions/check — N-way ATC interaction check (2–50 drugs); returns severity_max.
- GET /atc/{code} (+ /children, + /drugs) — WHO ATC tree, multilingual labels, DDD.
- GET /changes?since=<ts> — diff change feed.
- POST /webhooks, DELETE /webhooks — manage signed webhook subscriptions.
- GET /openapi.json — the OpenAPI document.

## Pricing
- Developer — Free, 100 requests/day.
- Starter — CHF 99/mo (250k req/mo, 99.5% SLA).
- Growth — CHF 490/mo (2M req/mo, 99.9% SLA, embeddable widget, HCI BYOL passthrough).
- Enterprise — from CHF 2.5k/mo (unlimited, self-host, custom DPA, SSO).
- [Pricing](https://drug-database.com/pricing)

## Compare
- [vs HCI Documedis](https://drug-database.com/alternatives/hci-documedis-vs-drug-database)
- [vs oddb.org](https://drug-database.com/alternatives/oddb-vs-drug-database)
- [vs openFDA](https://drug-database.com/alternatives/openfda-vs-drug-database)

## For developers
- [Capabilities overview](https://drug-database.com/capabilities)
- [Solutions overview](https://drug-database.com/solutions)
- [API docs](https://drug-database.com/docs)
- [MCP server](https://drug-database.com/mcp)
- [Status](https://drug-database.com/status)

## Company
- Drug Database, Geneva, Switzerland.
- Contact: hello@drug-database.com