United Kingdom· GB-APID-40456811000001101
Kaftrio 37.5mg/25mg/50mg tablets
A ivacaftor, tezacaftor and elexacaftor product containing ivacaftor + tezacaftor + elexacaftor, registered in United Kingdom by Vertex Pharmaceuticals (Europe) Ltd. The same ATC class is registered in 14 of our 19 countries.
Checked against NHS dm+d (United Kingdom) on
Informational only — not a medical device.
Where it is registered
Ivacaftor, tezacaftor and elexacaftor is registered in 14 of 19 countries.
Countries holding a registration under ATC R07AX32 (ivacaftor, tezacaftor and elexacaftor), each read from that country’s own register.
- This record: United Kingdom, from NHS dm+d (United Kingdom)
- 9 of them publish a price we can compare per daily dose
Ivacaftor, tezacaftor and elexacaftor · ATC R07AX32
14 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Spainprice
- Switzerlandprice
- United Kingdom
The record
At a glance
NHS dm+d (United Kingdom)- Active substance
- Ivacaftor + Tezacaftor + Elexacaftor
- Manufacturer
- Vertex Pharmaceuticals (Europe) Ltd
- Country
- United Kingdom (GB)
- ATC code
- R07AX32
- ATC class
- Ivacaftor, tezacaftor and elexacaftor
- Reimbursed
- Not published by this register
- Source register
- NHS dm+d (United Kingdom)
- Last checked
- September 13, 2026
Packs & prices · 2
- gtin00351167146101
- gtin00351167146002
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
14 interactions on record for ivacaftor, tezacaftor and elexacaftor.
Graded by severity as the source publishes them — 14 moderate. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Ivacaftor, tezacaftor and elexacaftor · interactions on record
14 records
- 14 moderate
Most severe, free to view
- RifaximinA07AA11moderate
- EmpagliflozinA10BK03moderate
- RepaglinideA10BX02moderate
- EmpagliflozinA10BX12moderate
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Ivacaftor, tezacaftor and elexacaftor in 12 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- CanadaTRIKAFTAVERTEX PHARMACEUTICALS (CANADA) INCORPORATED
- SwitzerlandTrikafta 100 mg / 50 mg / 75 mg, 150 mg, FilmtablettenVertex Pharmaceuticals (CH) GmbH
- CzechiaKAFTRIOVertex Pharmaceuticals (Ireland) Limited, Dublin
- SpainKAFTRIO 37,5 MG/25 MG/50 MG COMPRIMIDOS RECUBIERTOS CON PELICULAVertex Pharmaceuticals (Ireland) Limited
- FinlandKaftrioVertex Pharmaceuticals (Europe) Limited
- FranceKAFTRIO 37,5 mg/25 mg/50 mg, comprimé pelliculéVERTEX PHARMACEUTICALS (IRELAND)
- SwedenKaftrio 37,5 mg/25 mg/50 mg Filmdragerad tablettVertex Pharmaceuticals Ireland Ltd
- IrelandKaftrio 37.5 mg/25 mg/50 mg film-coated tabletsVertex Pharmaceuticals (Ireland) Limited
Authorised across Europe · EMA
The same active substance is authorised in 3 EEA countries. Names it is sold under:
- Iceland · Kaftrio
- Liechtenstein · Kaftrio
- Norway · Kaftrio
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of NHS dm+d (United Kingdom). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/6b068073-2bd8-4fff-929c-4543d1eb3783 GET /v1/drugs/6b068073-2bd8-4fff-929c-4543d1eb3783?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"apid": "40456811000001101",
"desc": "Kaftrio 37.5mg/25mg/50mg tablets (Vertex Pharmaceuticals (Europe) Ltd)",
"form": "Oral tablet",
"vpid": "40470511000001103",
"source": "dmd",
"vtm_id": "827103004",
"strength": "37.5 mg",
"substance": "Ivacaftor + Tezacaftor + Elexacaftor",
"ingredient": "Ivacaftor",
"supplier_code": "21148411000001105"
}See everything about ivacaftor, tezacaftor and elexacaftor.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.