Czechia· CZ-0220765

DOLIRIEF

A ibuprofen product containing ibuprofen lysine, registered in Czechia by Alkaloid - INT d.o.o., Ljubljana - Črnuče. The same ATC class is registered in 12 of our 19 countries.

ATC M01AE01

Checked against SÚKL (Czech Republic) on September 28, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about ibuprofen lysineAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Ibuprofen is registered in 12 of 19 countries.

Countries holding a registration under ATC M01AE01 (ibuprofen), each read from that country’s own register.

This record: Czechia, from SÚKL (Czech Republic)
8 of them publish a price we can compare per daily dose

Search ibuprofen products by name

Ibuprofen · ATC M01AE01

12 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Icelandprice
Ireland
Italyprice
Netherlands
Norwayprice
Polandprice
Switzerlandprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of ibuprofen costs, country by country.

Normalised to the WHO defined daily dose (1.2 g), the median price runs from $0.28 in Italy to $1.24 in Switzerland — a ×4.4 gap.

2 markets with a comparable price for this class
Public list prices, converted to USD at the rate date shown

Open the full comparison — free account Drug prices for market access

Ibuprofen · price per daily dose (1.2 g)

USD · FX 28 Sept 2026

CH Switzerland$1.24
IT Italy$0.28

Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

SÚKL (Czech Republic)

Active substance: IBUPROFEN LYSINE
Manufacturer: Alkaloid - INT d.o.o., Ljubljana - Črnuče
Country: Czechia (CZ)
ATC code: M01AE01
ATC class: Ibuprofen
Defined daily dose: 1.2 g, O
Reimbursed: Not published by this register
Source register: SÚKL (Czech Republic)
Last checked: September 28, 2026

Packs & prices · 0

No packs listed by the register for this record.

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

886 interactions on record for ibuprofen.

Graded by severity as the source publishes them — 71 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check ibuprofen against other medicines How interaction checks work

Ibuprofen · interactions on record

886 records

71 severe
306 moderate
15 minor
413 info

Most severe, free to view

DicoumarolB01AA01severe
WarfarinB01AA03severe
DalteparinB01AB04severe
EnoxaparinB01AB05severe

81 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Ibuprofen in 6 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All ibuprofen products

Authorised across Europe · EMA

The same active substance is authorised in 22 EEA countries. Names it is sold under:

Austria · Adolorin Ibuforte Express, Ibuprofen-Lysin Fairmed Healthcare
Belgium · Algidrin, Nurofen Lysine
Bulgaria · Блокмакс Рапид, Ибулек
Cyprus · Algofrenelle, Ultimax Alter
Germany · Ibu-Lysin, Ibu-Lysin - 1 A Pharma
Estonia · Ibumed
Spain · Algidrin, Algidrin Infantil
Finland · Ibumax Lysin, Ibuxin Rapid
France · Ibuprofene Cristers Conseil, Ibuprofene Lysinate Substipharm
United Kingdom (Northern Ireland) · Express Ibuprofen Lysine Superdrug, Express Pain Relief
Greece · Algofrenelle
Croatia · Blokmax Rapid, Brufen Effect Rapid
Hungary · Brufen, Dolowill Rapid
Italy · Algidrin Bambini, Arfen
Luxembourg · Algidrin, Ibu-Lysin
Malta · Algidrin, Algidrin Infantil
Netherlands · Ibuprofen Alkaloid-Int, Ibuprofen Innfarm
Poland · Byfonen, Ibuprofen Lysine Innfarm
Portugal · Brufenact, Bupalyn
Romania · Nurofen Ultra, Paduden Rapid
Slovenia · Dolirief, Ibubel Lin
Slovakia · Brufedol Rapid, Dolirief

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of SÚKL (Czech Republic). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/d6c7db33-aef9-4c97-a692-2953c5e4e98b
GET /v1/drugs/d6c7db33-aef9-4c97-a692-2953c5e4e98b?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "TBL FLM",
  "source": "sukl",
  "strength": "400MG",
  "pack_size": "20 I",
  "substance": "IBUPROFEN LYSINE",
  "cz_kod_sukl": "0220765",
  "product_type": "CH",
  "substance_codes": "11809",
  "registration_state": "R",
  "registration_number": "29/1047/16-C"
}

API reference MCP server Plans

See everything about ibuprofen.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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