Ireland· IE-PA-PA1701/013/001
Lirepin 400 mg film-coated tablets
A ibuprofen product containing ibuprofen lysine, registered in Ireland by Zentiva k.s.. The same ATC class is registered in 12 of our 19 countries.
Checked against HPRA (Ireland) on
Informational only — not a medical device.
Where it is registered
Ibuprofen is registered in 12 of 19 countries.
Countries holding a registration under ATC M01AE01 (ibuprofen), each read from that country’s own register.
- This record: Ireland, from HPRA (Ireland)
- 8 of them publish a price we can compare per daily dose
Ibuprofen · ATC M01AE01
12 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
Price per daily dose
What a daily dose of ibuprofen costs, country by country.
Normalised to the WHO defined daily dose (1.2 g), the median price runs from $0.28 in Italy to $1.24 in Switzerland — a ×4.4 gap.
- 2 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Ibuprofen · price per daily dose (1.2 g)
USD · FX 28 Sept 2026
- CH Switzerland$1.24
- IT Italy$0.28
The record
At a glance
HPRA (Ireland)- Active substance
- Ibuprofen lysine
- Manufacturer
- Zentiva k.s.
- Country
- Ireland (IE)
- ATC code
- M01AE01
- ATC class
- Ibuprofen
- Defined daily dose
- 1.2 g, O
- Reimbursed
- Not published by this register
- Source register
- HPRA (Ireland)
- Last checked
- September 28, 2026
Packs & prices · 1
- ie_pa_numberPA1701/013/001
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
886 interactions on record for ibuprofen.
Graded by severity as the source publishes them — 71 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Ibuprofen · interactions on record
886 records
- 71 severe
- 306 moderate
- 15 minor
- 413 info
Most severe, free to view
- DicoumarolB01AA01severe
- WarfarinB01AA03severe
- DalteparinB01AB04severe
- EnoxaparinB01AB05severe
81 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Ibuprofen in 6 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- CzechiaBRUFEN RAPIDVIATRIS LIMITED, Dublin
- BelgiumIbuprofen Lysine Mylan 400 mgViatris GX
- FinlandIbumax LysinVitabalans Oy
- United KingdomBoots Migraine Pain Relief Ibuprofen lysine 342mg tabletsThe Boots Company Plc
- GermanyIbu-LysinFairmed Healthcare Gmbh
- United StatesIbuprofen LysinePrasco Laboratories
Authorised across Europe · EMA
The same active substance is authorised in 23 EEA countries. Names it is sold under:
- Austria · Adolorin Ibuforte Express, Ibuprofen-Lysin Fairmed Healthcare
- Belgium · Algidrin, Nurofen Lysine
- Bulgaria · Блокмакс Рапид, Ибулек
- Cyprus · Algofrenelle, Ultimax Alter
- Czechia · Brufen Rapid, Dolirief
- Germany · Ibu-Lysin, Ibu-Lysin - 1 A Pharma
- Estonia · Ibumed
- Spain · Algidrin, Algidrin Infantil
- Finland · Ibumax Lysin, Ibuxin Rapid
- France · Ibuprofene Cristers Conseil, Ibuprofene Lysinate Substipharm
- United Kingdom (Northern Ireland) · Express Ibuprofen Lysine Superdrug, Express Pain Relief
- Greece · Algofrenelle
- Croatia · Blokmax Rapid, Brufen Effect Rapid
- Hungary · Brufen, Dolowill Rapid
- Italy · Algidrin Bambini, Arfen
- Luxembourg · Algidrin, Ibu-Lysin
- Malta · Algidrin, Algidrin Infantil
- Netherlands · Ibuprofen Alkaloid-Int, Ibuprofen Innfarm
- Poland · Byfonen, Ibuprofen Lysine Innfarm
- Portugal · Brufenact, Bupalyn
- Romania · Nurofen Ultra, Paduden Rapid
- Slovenia · Dolirief, Ibubel Lin
- Slovakia · Brufedol Rapid, Dolirief
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of HPRA (Ireland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/3e3513a2-e54e-45d3-9e05-9f4a6d53795e GET /v1/drugs/3e3513a2-e54e-45d3-9e05-9f4a6d53795e?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Film-coated tablet",
"routes": [
"Oral use"
],
"source": "hpra",
"atc_all": [
"M01AE01"
],
"strength": null,
"pa_number": "PA1701/013/001",
"substances": [
"Ibuprofen lysine"
],
"legal_basis": "Generic application (Article 10(1) of Directive No 2001/83/EC)",
"market_info": "Not marketed",
"authorised_at": "09/05/2025",
"dispensing_status": "Product not subject to medical prescription",
"registration_status": "AU",
"supply_legal_status": "Supply through pharmacies only",
"interchangeable_code": null
}See everything about ibuprofen.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.