Czechia· CZ-0258734

AKLIEF

A trifarotene product containing trifarotene, registered in Czechia by Galderma International, La Défense. The same ATC class is registered in 15 of our 19 countries.

ATC D10AD06

Checked against SÚKL (Czech Republic) on

Informational only — not a medical device.

SOURCE REGISTER · CZSÚKL (Czech Republic)normalisedAKLIEFATCD10AD06REGISTER NO.CZ-0258734PACKS LISTED1CHECKEDSeptember 28, 2026

Where it is registered

Trifarotene is registered in 15 of 19 countries.

Countries holding a registration under ATC D10AD06 (trifarotene), each read from that country’s own register.

  • This record: Czechia, from SÚKL (Czech Republic)
  • 9 of them publish a price we can compare per daily dose

Trifarotene · ATC D10AD06

15 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Franceprice
  • Germany
  • Icelandprice
  • Ireland
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

SÚKL (Czech Republic)
Active substance
TRIFAROTENE
Manufacturer
Galderma International, La Défense
Country
Czechia (CZ)
ATC code
D10AD06
ATC class
Trifarotene
Defined daily dose
50 mcg, T
Reimbursed
Not published by this register
Source register
SÚKL (Czech Republic)
Last checked
September 28, 2026

Packs & prices · 1

1 priced
  • cz_kod_sukl
    0258734
    1X75G
    CZK 954.03

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

9 interactions on record for trifarotene.

Graded by severity as the source publishes them — 1 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan

Trifarotene · interactions on record

9 records

  • 1 severe
  • 8 moderate

Most severe, free to view

  • Aminolevulinic acidL01XD04severe
  • Salicylic acidD01AE12moderate
  • IsotretinoinD10AD04moderate
  • Benzoyl peroxideD10AE01moderate
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Trifarotene in 15 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All trifarotene products

Authorised across Europe · EMA

The same active substance is authorised in 27 EEA countries. Names it is sold under:

  • Belgium · Aklief
  • Bulgaria · Аклиеф
  • Cyprus · Selgamis
  • Germany · Selgamis
  • Denmark · Aklief
  • Estonia · Aklief
  • Spain · Aklief
  • Finland · Aklief
  • France · Aklief
  • United Kingdom (Northern Ireland) · Aklief
  • Greece · Selgamis
  • Croatia · Aklief
  • Hungary · Aklief
  • Ireland · Aklief
  • Iceland · Aklief
  • Italy · Selgamis
  • Lithuania · Aklief
  • Luxembourg · Aklief
  • Latvia · Aklief
  • Malta · Aklief
  • Netherlands · Aklief
  • Norway · Aklief
  • Poland · Aklief
  • Portugal · Aklief
  • Romania · Aklief
  • Sweden · Aklief
  • Slovakia · Aklief

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of SÚKL (Czech Republic). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/d34deba6-8c4f-44ca-ad55-d7dd92dd426f
GET /v1/drugs/d34deba6-8c4f-44ca-ad55-d7dd92dd426f?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "CRM",
  "source": "sukl",
  "strength": "50MCG/G",
  "pack_size": "1X75G",
  "substance": "TRIFAROTENE",
  "cz_kod_sukl": "0258734",
  "product_type": "CH",
  "substance_codes": "19846",
  "registration_state": "R",
  "registration_number": "46/256/21-C"
}

See everything about trifarotene.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.