Netherlands· NL-ec651f11bf7c

Aklief 50 microgram/g crème

A trifarotene product containing trifaroteen, registered in Netherlands by Galderma Benelux B.V.. The same ATC class is registered in 15 of our 19 countries.

ATC D10AD06

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about trifaroteenAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Trifarotene is registered in 15 of 19 countries.

Countries holding a registration under ATC D10AD06 (trifarotene), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
9 of them publish a price we can compare per daily dose

Search trifarotene products by name

Trifarotene · ATC D10AD06

15 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Franceprice
Germany
Icelandprice
Ireland
Netherlands
Norwayprice
Polandprice
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

CBG-MEB (Netherlands)

Active substance: TRIFAROTEEN
Manufacturer: Galderma Benelux B.V.
Country: Netherlands (NL)
ATC code: D10AD06
ATC class: Trifarotene
Defined daily dose: 50 mcg, T
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
124058

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

9 interactions on record for trifarotene.

Graded by severity as the source publishes them — 1 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check trifarotene against other medicines How interaction checks work

Trifarotene · interactions on record

9 records

1 severe
8 moderate

Most severe, free to view

Aminolevulinic acidL01XD04severe
Salicylic acidD01AE12moderate
IsotretinoinD10AD04moderate
Benzoyl peroxideD10AE01moderate

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Trifarotene in 15 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All trifarotene products

Authorised across Europe · EMA

The same active substance is authorised in 27 EEA countries. Names it is sold under:

Belgium · Aklief
Bulgaria · Аклиеф
Cyprus · Selgamis
Czechia · Aklief
Germany · Selgamis
Denmark · Aklief
Estonia · Aklief
Spain · Aklief
Finland · Aklief
France · Aklief
United Kingdom (Northern Ireland) · Aklief
Greece · Selgamis
Croatia · Aklief
Hungary · Aklief
Ireland · Aklief
Iceland · Aklief
Italy · Selgamis
Lithuania · Aklief
Luxembourg · Aklief
Latvia · Aklief
Malta · Aklief
Norway · Aklief
Poland · Aklief
Portugal · Aklief
Romania · Aklief
Sweden · Aklief
Slovakia · Aklief

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/f1f760ed-4bc3-4570-854c-1bf2d6298c33
GET /v1/drugs/f1f760ed-4bc3-4570-854c-1bf2d6298c33?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Crème",
  "route": "Cutaan gebruik",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h124058_smpc.pdf",
  "strength": null,
  "atc_label": "Trifarotene",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg124058",
  "excipients": [
    "ALLANTOINE",
    "COPOLYMEER VAN ACRYLAMIDE-NATRIUM ACRYLOYLDIMETHYLTAURAAT-ISOHEXADECAAN",
    "CYCLOMETICON",
    "ETHANOL",
    "FENOXYETHANOL",
    "POLYSORBAAT 80 (E 433)",
    "PROPYLEENGLYCOL (E 1520)",
    "SORBITANMONOOLEAAT (E 494)",
    "TRIGLYCERIDEN MIDDELLANGE KETEN",
    "WATER, GEZUIVERD"
  ],
  "substances": [
    "TRIFAROTEEN"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h124058.pdf",
  "authorised_at": "2020/02/26",
  "procedure_number": "SE/H/1863/001",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "124058",
  "additional_monitoring": "N"
}

API reference MCP server Plans

See everything about trifarotene.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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