Switzerland· 58475001
Kuvan
A sapropterin product containing sapropterini dihydrochloridum, registered in Switzerland and dispensed under Swissmedic category B, on the national reimbursement list. The same ATC class is registered in 19 of our 19 countries.
Checked against BAG Spezialitätenliste (Switzerland) on
Informational only — not a medical device.
Where it is registered
Sapropterin is registered in 19 of 19 countries.
Countries holding a registration under ATC A16AX07 (sapropterin), each read from that country’s own register.
- This record: Switzerland, from BAG Spezialitätenliste (Switzerland)
- 11 of them publish a price we can compare per daily dose
Sapropterin · ATC A16AX07
19 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Spainprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of sapropterin costs, country by country.
Normalised to the WHO defined daily dose (0.7 g), so markets compare like for like.
- Switzerland: $159.61 per daily dose (median across products in the class)
- Public list prices, converted to USD at the rate date shown
Sapropterin · price per daily dose (0.7 g)
USD · FX 28 Sept 2026
- CH Switzerland$159.61
- IT Italy$156.69
The record
At a glance
BAG Spezialitätenliste (Switzerland)- Active substance
- sapropterini dihydrochloridum
- Manufacturer
- —
- Country
- Switzerland (CH)
- ATC code
- A16AX07
- ATC class
- Sapropterin
- Defined daily dose
- 0.7 g, O
- Swissmedic category
- B
- Reimbursed
- Yes
- Source register
- BAG Spezialitätenliste (Switzerland)
- Last checked
- September 12, 2026
Packs & prices · 1
1 priced- gtin7680584750015Fl 30 StkCHF 692.25
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
29 interactions on record for sapropterin.
Graded by severity as the source publishes them — 29 moderate. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Sapropterin · interactions on record
29 records
- 29 moderate
Most severe, free to view
- Glyceryl trinitrateC01DA02moderate
- Isosorbide dinitrateC01DA08moderate
- Isosorbide mononitrateC01DA14moderate
- NesiritideC01DX19moderate
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Sapropterin in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- NetherlandsArpetran 100 mg oplosbare tablettenPIAM Farmaceutici S.p.A.
- United StatesJAVYGTORDr. Reddys Laboratories Inc
- CzechiaKUVANBioMarin International Limited, Dublin
- IcelandKuvanBioMarin International Limited
- NorwaySapropterin DipharmaDipharma Arzneimittel GmbH
- FinlandKuvanBiomarin International Limited
- CanadaKUVANBIOMARIN INTERNATIONAL LIMITED
- United KingdomKuvan 100mg soluble tabletsBioMarin (U.K.) Ltd
Authorised across Europe · EMA
The same active substance is authorised in 15 EEA countries. Names it is sold under:
- Bulgaria · Сапроптерин Тева
- Czechia · Sapropterin Piam Farmaceutici
- Germany · Arpetran, Sapropterin Al
- Denmark · Arpetran, Sapropterin Sandoz
- Spain · Sapropterina Aurovitas, Sapropterina Elc
- France · Sapropterine Arrow, Sapropterine Teva
- United Kingdom (Northern Ireland) · Sapropterin Dihydrochloride, Sapropterin Dihydrochloride Amarox
- Iceland · Kuvan, Sapropterin Dipharma
- Italy · Arpetran, Sapropterina Aurobindo
- Liechtenstein · Kuvan, Sapropterin Dipharma
- Malta · Sapropterina Generis
- Netherlands · Arpetran, Sapropterin Aurobindo
- Norway · Kuvan, Sapropterin Dipharma
- Portugal · Arpetran, Sapropterina Generis
- Sweden · Sapropterin Stada, Sapropterin Teva
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of BAG Spezialitätenliste (Switzerland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/ca0bdbe3-7f2b-46ac-8a8e-58351772f15c GET /v1/drugs/ca0bdbe3-7f2b-46ac-8a8e-58351772f15c?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"unit": null,
"strength": "sapropterini dihydrochloridum 100 mg",
"valid_from": "2026-02-01",
"limitations": "[{\"description\":\"Bei angeborenen und nachgewiesenen BH4-Synthesedefekten (auch bekannt als atypische Phenylketonurie). Zudem bei Patienten mit Phenylketonurie, die voll auf Kuvan ansprechen müssen, d.h. sog. full responders sind.\",\"costApproval\":null,\"indication\":\"\",\"isNew\":false,\"limitationCode\":null,\"points\":null,\"priceModel\":null,\"title\":null,\"validFrom\":\"2014-06-01\",\"validTo\":null}]",
"galenic_form": "Tabl 100 mg für Trinklsg",
"therapeutic_area": null,
"sl_inclusion_date": "2026-02-01",
"self_retention_pct": 10
}See everything about sapropterin.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.