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United Kingdom· GB-APID-15418311000001105

Kuvan 100mg soluble tablets

A sapropterin product containing sapropterin, registered in United Kingdom by BioMarin (U.K.) Ltd. The same ATC class is registered in 19 of our 19 countries.

ATC A16AX07

Checked against NHS dm+d (United Kingdom) on

Informational only — not a medical device.

SOURCE REGISTER · GBNHS dm+d (United Kingdom)normalisedKuvan 100mg soluble tabletsATCA16AX07REGISTER NO.GB-APID-1541831100000…PACKS LISTED3CHECKEDSeptember 13, 2026
Compare price across countriesPer daily dose · free accountAsk the assistant about sapropterinAnswers with sources · free accountCheck interactionsSeverity free · mechanism on Growth

Where it is registered

Sapropterin is registered in 19 of 19 countries.

Countries holding a registration under ATC A16AX07 (sapropterin), each read from that country’s own register.

  • This record: United Kingdom, from NHS dm+d (United Kingdom)
  • 11 of them publish a price we can compare per daily dose
Search sapropterin products by name

Sapropterin · ATC A16AX07

19 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Franceprice
  • Germany
  • Icelandprice
  • Ireland
  • Italyprice
  • Japan
  • Netherlands
  • Norwayprice
  • Polandprice
  • Spainprice
  • Sweden
  • Switzerlandprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of sapropterin costs, country by country.

Normalised to the WHO defined daily dose (0.7 g), so markets compare like for like.

  • 2 markets with a comparable price for this class
  • Public list prices, converted to USD at the rate date shown
Open the full comparison — free accountDrug prices for market access

Sapropterin · price per daily dose (0.7 g)

USD · FX 28 Sept 2026

  • CH Switzerland$159.61
  • IT Italy$156.69
Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

NHS dm+d (United Kingdom)
Active substance
Sapropterin
Manufacturer
BioMarin (U.K.) Ltd
Country
United Kingdom (GB)
ATC code
A16AX07
ATC class
Sapropterin
Defined daily dose
0.7 g, O
Reimbursed
Not published by this register
Source register
NHS dm+d (United Kingdom)
Last checked
September 13, 2026

Packs & prices · 3

  • gtin
    5013837321762
  • gtin
    05391524460742
  • gtin
    5013837321755

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

29 interactions on record for sapropterin.

Graded by severity as the source publishes them — 29 moderate. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan
Check sapropterin against other medicinesHow interaction checks work

Sapropterin · interactions on record

29 records

  • 29 moderate

Most severe, free to view

  • Glyceryl trinitrateC01DA02moderate
  • Isosorbide dinitrateC01DA08moderate
  • Isosorbide mononitrateC01DA14moderate
  • NesiritideC01DX19moderate
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Sapropterin in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All sapropterin products

Authorised across Europe · EMA

The same active substance is authorised in 14 EEA countries. Names it is sold under:

  • Bulgaria · Сапроптерин Тева
  • Czechia · Sapropterin Piam Farmaceutici
  • Germany · Arpetran, Sapropterin Al
  • Denmark · Arpetran, Sapropterin Sandoz
  • Spain · Sapropterina Aurovitas, Sapropterina Elc
  • France · Sapropterine Arrow, Sapropterine Teva
  • Iceland · Kuvan, Sapropterin Dipharma
  • Italy · Arpetran, Sapropterina Aurobindo
  • Liechtenstein · Kuvan, Sapropterin Dipharma
  • Malta · Sapropterina Generis
  • Netherlands · Arpetran, Sapropterin Aurobindo
  • Norway · Kuvan, Sapropterin Dipharma
  • Portugal · Arpetran, Sapropterina Generis
  • Sweden · Sapropterin Stada, Sapropterin Teva

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of NHS dm+d (United Kingdom). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/97045877-6ad0-4972-a480-9f64e897a92f
GET /v1/drugs/97045877-6ad0-4972-a480-9f64e897a92f?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "apid": "15418311000001105",
  "desc": "Kuvan 100mg soluble tablets (BioMarin (U.K.) Ltd)",
  "form": "Soluble tablet",
  "vpid": "15499611000001108",
  "source": "dmd",
  "vtm_id": "777496006",
  "strength": "100 mg",
  "substance": "Sapropterin",
  "ingredient": "Sapropterin dihydrochloride",
  "supplier_code": "10075811000001102"
}
API referenceMCP serverPlans

See everything about sapropterin.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it freeOpen in the console