Switzerland· 53112005
Valproate Chrono Sanofi 300 mg, comprimés à libération prolongée
A valproic acid product containing acidum valproicum, natrii valproas, registered in Switzerland by Sanofi-Aventis (Suisse) SA and dispensed under Swissmedic category B, on the national reimbursement list. The same ATC class is registered in 16 of our 19 countries.
Checked against Swissmedic (Switzerland) on
Informational only — not a medical device.
Where it is registered
Valproic acid is registered in 16 of 19 countries.
Countries holding a registration under ATC N03AG01 (valproic acid), each read from that country’s own register.
- This record: Switzerland, from Swissmedic (Switzerland)
- 9 of them publish a price we can compare per daily dose
Valproic acid · ATC N03AG01
16 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of valproic acid costs, country by country.
Normalised to the WHO defined daily dose (1.5 g), so markets compare like for like.
- Switzerland: $1.61 per daily dose (median across products in the class)
- Public list prices, converted to USD at the rate date shown
Valproic acid · price per daily dose (1.5 g)
USD · FX 28 Sept 2026
- CH Switzerland$1.61
The record
At a glance
Swissmedic (Switzerland)- Active substance
- acidum valproicum, natrii valproas
- Manufacturer
- Sanofi-Aventis (Suisse) SA
- Country
- Switzerland (CH)
- ATC code
- N03AG01
- ATC class
- Valproic acid
- Defined daily dose
- 1.5 g, O
- Swissmedic category
- B
- Reimbursed
- Yes
- Source register
- Swissmedic (Switzerland)
- Last checked
- September 12, 2026
Packs & prices · 1
1 priced- gtin7680531120052Blist 100 StkCHF 26.05
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
391 interactions on record for valproic acid.
Graded by severity as the source publishes them — 9 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Valproic acid · interactions on record
391 records
- 9 severe
- 132 moderate
- 23 minor
- 189 info
Most severe, free to view
- Glycerol phenylbutyrateA16AX09severe
- BexaroteneL01XF03severe
- VorinostatL01XH01severe
- BexarotenL01XX25severe
38 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Valproic acid in 6 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- GermanyErgenyl ChronoSanofi-Aventis Deutschland Gmbh
- FinlandDeprakinesanofi-aventis Oy
- PolandDepakine Chrono 300Sanofi Sp. z o.o.
- IrelandEpilim Chrono 200mg Prolonged Release TabletsSanofi-Aventis Ireland Limited T/A SANOFI
- SwedenErgenyl Retard 100 mg Depotgranulat i dospåseSanofi AB
- NorwayErgenyl chronosanofi-aventis (2)
Authorised across Europe · EMA
The same active substance is authorised in 27 EEA countries. Names it is sold under:
- Austria · Depakine Chrono Retard, Depakine Chronosphere
- Belgium · Depakine Chrono, Valproate Retard Eg
- Bulgaria · Депакин Хроно
- Cyprus · Depakine Chrono
- Czechia · Depakine Chrono, Valproat
- Germany · Ergenyl Chrono, Orfiril
- Estonia · Depakine Chrono
- Spain · Ácido Valproico Aurovitas, Depakine Crono
- Finland · Deprakine
- France · Depakine Chrono, Micropakine L.P.
- United Kingdom (Northern Ireland) · Alprolep 200mg Prolonged-Release Tablets, Alprolep 300mg Prolonged-Release Tablets
- Greece · Depakine Chrono, Depakine Chrono (Sphere)
- Croatia · Depakine Chrono
- Hungary · Depakine Chrono
- Ireland · Epilim Chrono, Epilim Chronosphere
- Italy · Acido Valproico E Sodio Valproato Eg, Acido Valproico E Sodio Valproato Ratiopharm
- Lithuania · Depakine Chrono, Depakine Chronosphere
- Luxembourg · Depakine Chrono, Valproate Retard Eg
- Latvia · Depakine Chrono
- Malta · Epilim Chrono
- Netherlands · Depakine Chrono, Depakine Chronosphere
- Poland · Depakine Chrono 300, Depakine Chrono 500
- Portugal · Ácido Valpróico Aurovitas, Ácido Valpróico Generis
- Romania · Depakine Chrono
- Sweden · Ergenyl Retard
- Slovenia · Depakine Chrono
- Slovakia · Depakine Chrono, Valpro Chrono
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Swissmedic (Switzerland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/ae029f3e-b8db-440f-aae8-39cf101fb9dc GET /v1/drugs/ae029f3e-b8db-440f-aae8-39cf101fb9dc?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"unit": null,
"strength": "natrii valproas 300 mg",
"valid_from": "2018-12-01",
"limitations": null,
"galenic_form": "Filmtabl 300 mg",
"therapeutic_area": null,
"sl_inclusion_date": "2012-02-01",
"self_retention_pct": 10
}See everything about valproic acid.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.