Netherlands· NL-92c3afbd7858
Cuprior150 mg, tablet
A trientine product containing triëntinetetrahydrochloride, registered in Netherlands by GMP-Orphan SAS. The same ATC class is registered in 19 of our 19 countries.
Checked against CBG-MEB (Netherlands) on
Informational only — not a medical device.
Where it is registered
Trientine is registered in 19 of 19 countries.
Countries holding a registration under ATC A16AX12 (trientine), each read from that country’s own register.
- This record: Netherlands, from CBG-MEB (Netherlands)
- 11 of them publish a price we can compare per daily dose
Trientine · ATC A16AX12
19 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Spainprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of trientine costs, country by country.
Normalised to the WHO defined daily dose (0.45 g), the median price runs from $97.54 in Switzerland to $186.45 in Italy — a ×1.9 gap.
- 2 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Trientine · price per daily dose (0.45 g)
USD · FX 28 Sept 2026
- IT Italy$186.45
- CH Switzerland$97.54
The record
At a glance
CBG-MEB (Netherlands)- Active substance
- TRIËNTINETETRAHYDROCHLORIDE
- Manufacturer
- GMP-Orphan SAS
- Country
- Netherlands (NL)
- ATC code
- A16AX12
- ATC class
- Trientine
- Defined daily dose
- 0.45 g, O
- Reimbursed
- Not published by this register
- Source register
- CBG-MEB (Netherlands)
- Last checked
- September 29, 2026
Packs & prices · 1
- cbg_meb_idEU/1/17/1199
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
35 interactions on record for trientine.
Graded by severity as the source publishes them — 31 moderate. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Trientine · interactions on record
35 records
- 31 moderate
- 4 minor
Most severe, free to view
- Magnesium carbonateA02AA01moderate
- Magnesium oxideA02AA02moderate
- Magnesium hydroxideA02AA04moderate
- Kombinationen von AluminiumsalzenA02AB10moderate
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Trientine in 15 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United KingdomCuprior 150mg tabletsOrphalan UK Ltd
- NorwayCupriorOrphalan
- SwedenCuprior 150 mg TablettOrphalan
- SwitzerlandCuprior
- CzechiaCUFENCEUnivar Solutions B.V., Rotterdam
- United StatesSyprineBausch Health US LLC
- FinlandCufenceUnivar Solutions BV
- FranceCUFENCE 100 mg, géluleUNIVAR SOLUTIONS (PAYS-BAS)
Authorised across Europe · EMA
The same active substance is authorised in 19 EEA countries. Names it is sold under:
- Austria · Aveleris, Trientin
- Belgium · Aveleris
- Czechia · Trientine Tillomed
- Germany · Aveleris, Trientin Waymade
- Denmark · Trientin Waymade, Trientine Tillomed
- Spain · Trientina
- Finland · Trientine Tillomed, Trientine Waymade
- France · Trientine Tillomed, Trientine Waymade
- United Kingdom (Northern Ireland) · Trientine, Trientine Dihydrochloride Tillomed
- Greece · Trientine Tillomed, Trientine Waymade
- Ireland · Trientine Tillomed, Trientine Tillomed Pharma
- Iceland · Cufence, Cuprior
- Italy · Trientina Ideogen, Trientina Waymade
- Liechtenstein · Cufence, Cuprior
- Luxembourg · Aveleris
- Norway · Cufence, Cuprior
- Portugal · Trientina Tillomed, Trientina Waymade
- Sweden · Trientine Tillomed, Trientine Waymade
- Slovakia · Trientine Tillomed
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/567ce728-cdc9-4c60-bfcd-e3d3ad048641 GET /v1/drugs/567ce728-cdc9-4c60-bfcd-e3d3ad048641?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Tablet",
"route": "Oraal gebruik",
"soort": null,
"source": "cbg_meb",
"smpc_url": "https://www.ema.europa.eu/en/documents/product-information/cuprior-epar-product-information_nl.pdf",
"strength": null,
"atc_label": "Trientine",
"detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/cp118567",
"excipients": [
"GLYCEROL MONOCAPRYLOCAPRAAT, TYPE I",
"GLYCEROLDIBEHENAAT",
"IJZEROXIDE GEEL (E 172)",
"MANNITOL (D-) (E 421)",
"NATRIUMLAURILSULFAAT",
"POLYVINYLALCOHOL, GEDEELTELIJK GEHYDROLYSEERD (E1203)",
"SILICIUMDIOXIDE (E 551)",
"TALK (E 553b)",
"TITAANDIOXIDE (E 171)"
],
"substances": [
"TRIËNTINETETRAHYDROCHLORIDE"
],
"leaflet_url": null,
"authorised_at": "2017/09/05",
"procedure_number": "EMEA/H/C/004005",
"dispensing_status": "Uitsluitend recept",
"registration_number": "EU/1/17/1199",
"additional_monitoring": "N"
}See everything about trientine.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.