France· FR:68588478
CUFENCE 100 mg, gélule
A trientine product containing dichlorhydrate de trientine, registered in France by UNIVAR SOLUTIONS (PAYS-BAS), on the national reimbursement list. The same ATC class is registered in 19 of our 19 countries.
Checked against Base de données publique des médicaments — BDPM (France) on
Informational only — not a medical device.
Where it is registered
Trientine is registered in 19 of 19 countries.
Countries holding a registration under ATC A16AX12 (trientine), each read from that country’s own register.
- This record: France, from Base de données publique des médicaments — BDPM (France)
- 11 of them publish a price we can compare per daily dose
Trientine · ATC A16AX12
19 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Spainprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of trientine costs, country by country.
Normalised to the WHO defined daily dose (0.45 g), the median price runs from $97.54 in Switzerland to $186.45 in Italy — a ×1.9 gap.
- 2 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Trientine · price per daily dose (0.45 g)
USD · FX 28 Sept 2026
- IT Italy$186.45
- CH Switzerland$97.54
The record
At a glance
Base de données publique des médicaments — BDPM (France)- Active substance
- DICHLORHYDRATE DE TRIENTINE
- Manufacturer
- UNIVAR SOLUTIONS (PAYS-BAS)
- Country
- France (FR)
- ATC code
- A16AX12
- ATC class
- Trientine
- Defined daily dose
- 0.45 g, O
- Reimbursed
- Yes
- Source register
- Base de données publique des médicaments — BDPM (France)
- Last checked
- September 12, 2026
Packs & prices · 1
1 priced- cip1334009302802011 flacon(s) en verre jaune(brun) avec fermeture de sécurité enfant de 200 gélule(s)EUR 2.21
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
35 interactions on record for trientine.
Graded by severity as the source publishes them — 31 moderate. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Trientine · interactions on record
35 records
- 31 moderate
- 4 minor
Most severe, free to view
- Magnesium carbonateA02AA01moderate
- Magnesium oxideA02AA02moderate
- Magnesium hydroxideA02AA04moderate
- Kombinationen von AluminiumsalzenA02AB10moderate
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Trientine in 15 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- BelgiumCufence 100 mgUnivar Solutions
- CzechiaCUFENCEUnivar Solutions B.V., Rotterdam
- FinlandCufenceUnivar Solutions BV
- United KingdomCufence 100mg capsulesUnivar Solutions B.V.
- IrelandCufence 100 mg hard capsuleUnivar B.V
- IcelandCufenceUnivar Solutions B.V.
- NetherlandsCufence 100 mg harde capsulesUnivar B.V.
- SwedenCufence 100 mg Kapsel, hårdUnivar Solutions B.V.
Authorised across Europe · EMA
The same active substance is authorised in 19 EEA countries. Names it is sold under:
- Austria · Aveleris, Trientin
- Belgium · Aveleris
- Czechia · Trientine Tillomed
- Germany · Aveleris, Trientin Waymade
- Denmark · Trientin Waymade, Trientine Tillomed
- Spain · Trientina
- Finland · Trientine Tillomed, Trientine Waymade
- United Kingdom (Northern Ireland) · Trientine, Trientine Dihydrochloride Tillomed
- Greece · Trientine Tillomed, Trientine Waymade
- Ireland · Trientine Tillomed, Trientine Tillomed Pharma
- Iceland · Cufence, Cuprior
- Italy · Trientina Ideogen, Trientina Waymade
- Liechtenstein · Cufence, Cuprior
- Luxembourg · Aveleris
- Netherlands · Aveleris, Trientine Waymade
- Norway · Cufence, Cuprior
- Portugal · Trientina Tillomed, Trientina Waymade
- Sweden · Trientine Tillomed, Trientine Waymade
- Slovakia · Trientine Tillomed
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Base de données publique des médicaments — BDPM (France). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/58e414c2-b008-4c80-8a24-79bbc0b1989f GET /v1/drugs/58e414c2-b008-4c80-8a24-79bbc0b1989f?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"cis": "68588478",
"date_amm": "2023-11-23",
"type_amm": "Procédure centralisée",
"numero_ue": "EU/1/19/1365",
"substance": "DICHLORHYDRATE DE TRIENTINE",
"atc_source": "fr_atc_restore_2026-09-06",
"statut_amm": "Autorisation active",
"statut_bdm": null,
"forme_pharmaceutique": "gélule",
"voies_administration": "orale",
"etat_commercialisation": "Commercialisée",
"surveillance_renforcee": "Non"
}See everything about trientine.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.