United States· US:0404-9828_d06af667-46dd-4cf0-84fa-87e9be2d6d77
Bupivacaine Hydrochloride and Epinephrine
A medicinal product containing bupivacaine hydrochloride; epinephrine bitartrate, registered in United States by Henry Schein, Inc..
Checked against FDA National Drug Code directory (United States) on
Informational only — not a medical device.
The record
At a glance
FDA National Drug Code directory (United States)- Active substance
- BUPIVACAINE HYDROCHLORIDE; EPINEPHRINE BITARTRATE
- Manufacturer
- Henry Schein, Inc.
- Country
- United States (US)
- ATC code
- —
- Reimbursed
- Not published by this register
- Source register
- FDA National Drug Code directory (United States)
- Last checked
- September 27, 2026
Packs & prices · 2
- ndc1104049828301 VIAL, SINGLE-DOSE in 1 BAG (0404-9828-30) / 30 mL in 1 VIAL, SINGLE-DOSE
- ndc110404-9828-30
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Same medicine, other countries
Bupivacaine hydrochloride; epinephrine bitartrate in 8 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United KingdomBupivacaine 25mg/10ml (0.25%) / Adrenaline (base) 50micrograms/10ml (1 in 200,000) solution for injection ampoulesAdvanz Pharma
- CanadaBUPIVACAINE HCL 0.5% AND EPINEPHRINE 1:200,000 INJECTIONNOVOCOL PHARMACEUTICAL OF CANADA INC
- FinlandApiyaqMacure Pharma ApS
- IrelandMarcain 0.25% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for InjectionAspen Pharma Trading Limited
- SwedenApiyaq 2,5 mg/ml + 5 mikrogram/ml Injektionsvätska, lösningMACURE PHARMA ApS
- SwitzerlandCarbostesin-Adrenalin 2,5 mg/ml, Injektions-/InfusionslösungAspen Pharma Schweiz GmbH
- GermanyBupivacain Mit Epinephrin JenapharmMibe Gmbh Arzneimittel
- PolandMarcaine - Adrenaline 0,5%Aspen Pharma Trading Ltd.
Authorised across Europe · EMA
The same active substance is authorised in 6 EEA countries. Names it is sold under:
- Denmark · Apiyaq
- Spain · Bupivacaína + Epinefrina Physan, Inibsacain
- Finland · Apiyaq
- Italy · Bupicain Con Adrenalina
- Norway · Apiyaq
- Sweden · Apiyaq
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/05ae857e-3edb-4220-ad14-0a51223da880 GET /v1/drugs/05ae857e-3edb-4220-ad14-0a51223da880?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"route": "EPIDURAL; INFILTRATION; INTRACAUDAL; PERINEURAL",
"source": "ndc",
"strength": "2.5; 5",
"substance": "BUPIVACAINE HYDROCHLORIDE; EPINEPHRINE BITARTRATE",
"productndc": "0404-9828",
"dosage_form": "INJECTION, SOLUTION",
"dea_schedule": null,
"strength_unit": "mg/mL; ug/mL",
"application_number": "ANDA071165",
"marketing_category": "ANDA"
}See everything about bupivacaine hydrochloride; epinephrine bitartrate.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.