Canada· CA-DIN-02381850
BUPIVACAINE HCL 0.5% AND EPINEPHRINE 1:200,000 INJECTION
A bupivacain, kombinationen product containing epinephrine bitartrate + bupivacaine hydrochloride, registered in Canada by NOVOCOL PHARMACEUTICAL OF CANADA INC. The same ATC class is registered in 10 of our 19 countries.
Checked against Health Canada Drug Product Database (Canada) on
Informational only — not a medical device.
Where it is registered
Bupivacain, kombinationen is registered in 10 of 19 countries.
Countries holding a registration under ATC N01BB51 (bupivacain, kombinationen), each read from that country’s own register.
- This record: Canada, from Health Canada Drug Product Database (Canada)
- 6 of them publish a price we can compare per daily dose
Bupivacain, kombinationen · ATC N01BB51
10 / 19 countries
- Belgiumprice
- Canada
- Denmark
- Finlandprice
- Icelandprice
- Ireland
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
The record
At a glance
Health Canada Drug Product Database (Canada)- Active substance
- EPINEPHRINE BITARTRATE + BUPIVACAINE HYDROCHLORIDE
- Manufacturer
- NOVOCOL PHARMACEUTICAL OF CANADA INC
- Country
- Canada (CA)
- ATC code
- N01BB51
- ATC class
- Bupivacain, Kombinationen
- Reimbursed
- Not published by this register
- Source register
- Health Canada Drug Product Database (Canada)
- Last checked
- October 1, 2026
Packs & prices · 0
No packs listed by the register for this record.
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Same medicine, other countries
Bupivacain, kombinationen in 8 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United StatesBUPIVACAINE HCI AND EPINEPHRINEHF Acquisition Co LLC, DBA HealthFirst
- United KingdomBupivacaine 25mg/10ml (0.25%) / Adrenaline (base) 50micrograms/10ml (1 in 200,000) solution for injection ampoulesA A H Pharmaceuticals Ltd
- FinlandApiyaqMacure Pharma ApS
- IrelandMarcain 0.25% w/v with Adrenaline (Epinephrine, 5 micrograms per ml) (1:200,000) Solution for InjectionAspen Pharma Trading Limited
- SwedenApiyaq 2,5 mg/ml + 5 mikrogram/ml Injektionsvätska, lösningMACURE PHARMA ApS
- SwitzerlandCarbostesin-Adrenalin 2,5 mg/ml, Injektions-/InfusionslösungAspen Pharma Schweiz GmbH
- GermanyBupivacain Mit Epinephrin JenapharmMibe Gmbh Arzneimittel
- PolandMarcaine - Adrenaline 0,5%Aspen Pharma Trading Ltd.
Authorised across Europe · EMA
The same active substance is authorised in 6 EEA countries. Names it is sold under:
- Denmark · Apiyaq
- Spain · Bupivacaína + Epinefrina Physan, Inibsacain
- Finland · Apiyaq
- Italy · Bupicain Con Adrenalina
- Norway · Apiyaq
- Sweden · Apiyaq
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Health Canada Drug Product Database (Canada). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/83cd6c49-99b5-46bb-81dd-373b63825ef7 GET /v1/drugs/83cd6c49-99b5-46bb-81dd-373b63825ef7?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"din": "02381850",
"form": "SOLUTION",
"class": "Human",
"routes": [
"BLOCK/INFILTRATION"
],
"source": "health_canada_dpd",
"status": "MARKETED",
"atc_raw": "N01BB51",
"schedule": [
"Ethical"
],
"drug_code": "86769",
"strengths": [
"0.0091 MG",
"5 MG"
],
"ahfs_class": null,
"substances": [
"EPINEPHRINE BITARTRATE",
"BUPIVACAINE HYDROCHLORIDE"
],
"product_categorization": null
}See everything about bupivacain, kombinationen.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.