Netherlands· NL-366fd79d1624

Otrivin Duo Xylometazolinehydrochloride & Ipratropiumbromide, 0,5/0,6 mg/ml, neusspray, oplossing

A xylometazoline product containing ipratropiumbromide 0-water + xylometazolinehydrochloride, registered in Netherlands by Haleon Netherlands B.V.. The same ATC class is registered in 10 of our 19 countries.

ATC R01AB06

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about ipratropiumbromide 0-water + xylometazolinehydrochlorideAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Xylometazoline is registered in 10 of 19 countries.

Countries holding a registration under ATC R01AB06 (xylometazoline), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
7 of them publish a price we can compare per daily dose

Search xylometazoline products by name

Xylometazoline · ATC R01AB06

10 / 19 countries

Belgiumprice
Czechiaprice
Denmark
Finlandprice
Icelandprice
Ireland
Netherlands
Norwayprice
Polandprice
Switzerlandprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

CBG-MEB (Netherlands)

Active substance: IPRATROPIUMBROMIDE 0-WATER + XYLOMETAZOLINEHYDROCHLORIDE
Manufacturer: Haleon Netherlands B.V.
Country: Netherlands (NL)
ATC code: R01AB06
ATC class: Xylometazoline
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
102338

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

63 interactions on record for xylometazoline.

Graded by severity as the source publishes them — 6 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check xylometazoline against other medicines How interaction checks work

Xylometazoline · interactions on record

63 records

6 severe
54 moderate

Most severe, free to view

MethylergometrineG02AB01severe
DihydroergotamineN02CA01severe
ErgotamineN02CA02severe
MethysergideN02CA04severe

3 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Xylometazoline in 9 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All xylometazoline products

Authorised across Europe · EMA

The same active substance is authorised in 26 EEA countries. Names it is sold under:

Austria · Otrivin Duo
Belgium · Otrivine Duo
Cyprus · Otrivin Advance
Czechia · Otrivin Duo
Denmark · Otrivin Comp, Zymelin Plus
Estonia · Otrivin Total
Spain · Rhinovin Duo
Finland · Otrivin Comp
United Kingdom (Northern Ireland) · Otrivine Extra Dual Relief
Greece · Otrivin Advance
Croatia · Ksilometazolinklorid/Ipratropijev Bromid Acino, Nasoryl
Hungary · Otrivin Komplex
Ireland · Otrivine Extra Dual Relief
Iceland · Otrivin Comp
Italy · Rinazina Doppia Azione
Lithuania · Otriduo
Luxembourg · Otrivine Duo
Latvia · Otrivin Total
Malta · Otrivine Extra Dual Relief
Norway · Otrivin Comp, Zycomb
Poland · Otrivin Ipra Max
Portugal · Nasitrim Duoeffect, Vibrocil Actilongduo
Romania · Rhinxyl Plus, Vibrocil Duo
Sweden · Otrivin Comp, Zymelin Comp
Slovenia · Maresyl Comb, Otrivin Duo
Slovakia · Otrivin Duo

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/ff1e22cc-610b-4365-affc-24215290b69e
GET /v1/drugs/ff1e22cc-610b-4365-affc-24215290b69e?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Neusspray, oplossing",
  "route": "Nasaal gebruik",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h102338_smpc.pdf",
  "strength": null,
  "atc_label": "Xylometazoline",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg102338",
  "excipients": [
    "DINATRIUMEDETAAT 2-WATER",
    "GLYCEROL (E 422)",
    "NATRIUMHYDROXIDE (E 524)",
    "WATER, GEZUIVERD",
    "ZOUTZUUR (E 507)"
  ],
  "substances": [
    "IPRATROPIUMBROMIDE 0-WATER",
    "XYLOMETAZOLINEHYDROCHLORIDE"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h102338.pdf",
  "authorised_at": "2009/07/09",
  "procedure_number": "SE/H/0848/001",
  "dispensing_status": "Uitsluitend apotheek of drogist",
  "registration_number": "102338",
  "additional_monitoring": "N"
}

API reference MCP server Plans

See everything about xylometazoline.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it free Open in the console