United Kingdom· GB-APID-94111000001105
Comtess 200mg tablets
A entacapone product containing entacapone, registered in United Kingdom by Orion Pharma (UK) Ltd. The same ATC class is registered in 18 of our 19 countries.
Checked against NHS dm+d (United Kingdom) on
Informational only — not a medical device.
Where it is registered
Entacapone is registered in 18 of 19 countries.
Countries holding a registration under ATC N04BX02 (entacapone), each read from that country’s own register.
- This record: United Kingdom, from NHS dm+d (United Kingdom)
- 10 of them publish a price we can compare per daily dose
Entacapone · ATC N04BX02
18 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of entacapone costs, country by country.
Normalised to the WHO defined daily dose (1 g), the median price runs from $1.87 in France to $6.60 in Switzerland — a ×3.5 gap.
- 3 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Entacapone · price per daily dose (1 g)
USD · FX 28 Sept 2026
- CH Switzerland$6.60
- IT Italy$6.27
- FR France$1.87
The record
At a glance
NHS dm+d (United Kingdom)- Active substance
- Entacapone
- Manufacturer
- Orion Pharma (UK) Ltd
- Country
- United Kingdom (GB)
- ATC code
- N04BX02
- ATC class
- Entacapone
- Defined daily dose
- 1 g, O
- Reimbursed
- Not published by this register
- Source register
- NHS dm+d (United Kingdom)
- Last checked
- September 13, 2026
Packs & prices · 4
- gtin6432100003607
- gtin6432100057556
- gtin6432100003614
- gtin6432100057563
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
110 interactions on record for entacapone.
Graded by severity as the source publishes them — 2 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Entacapone · interactions on record
110 records
- 2 severe
- 61 moderate
- 1 minor
- 46 info
Most severe, free to view
- ProcarbazineL01XB01severe
- Methylthioninium chlorideV03AB17severe
- EpinephrineA01AD01moderate
- MetoclopramideA03FA01moderate
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Entacapone in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- CanadaMINT-ENTACAPONEMINT PHARMACEUTICALS INC
- United StatesEntacaponeNCS HealthCare of KY, LLC dba Vangard Labs
- CzechiaCOMTANOrion Corporation, Espoo
- BelgiumComtan 200 mgOrion
- NetherlandsComtan, 200 mg omhulde tablettenOrion Corporation
- FinlandComtanOrifarm Oy
- SpainCOMTAN 200 mg COMPRIMIDOS RECUBIERTOS CON PELICULAOrion Corporation
- SwedenComtan 200 mg Filmdragerad tablettOrion Corporation
Authorised across Europe · EMA
The same active substance is authorised in 15 EEA countries. Names it is sold under:
- Cyprus · Encapia
- Germany · Entacapon Hec
- Denmark · Entacapone Viatris
- Spain · Entacapona Viatris, Medapia
- Finland · Entacapone Orion Pharma
- France · Entacapone Arrow, Entacapone Viatris
- Croatia · Entakapon Hec
- Iceland · Comtan, Comtess
- Liechtenstein · Comtan, Comtess
- Lithuania · Medapia
- Malta · Medapia
- Netherlands · Encapia, Entacapone Unichem
- Norway · Comtan, Comtess
- Portugal · Entacapona Aurobindo, Medapia
- Sweden · Entacapone Viatris
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of NHS dm+d (United Kingdom). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/fe4bb91b-38c9-44aa-9995-9e625556de53 GET /v1/drugs/fe4bb91b-38c9-44aa-9995-9e625556de53?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"apid": "94111000001105",
"desc": "Comtess 200mg tablets (Orion Pharma (UK) Ltd)",
"form": "Oral tablet",
"vpid": "42035811000001108",
"source": "dmd",
"vtm_id": "775773008",
"strength": "200 mg",
"substance": "Entacapone",
"ingredient": "Entacapone",
"supplier_code": "2574501000001106"
}See everything about entacapone.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.