Netherlands· NL-4e360260ea77
Madopar HBS 125 mg, capsules met gereguleerde afgifte
A levodopa und decarboxylasehemmer product containing benserazidehydrochloride + levodopa, registered in Netherlands by Roche Nederland B.V.. The same ATC class is registered in 12 of our 19 countries.
Checked against CBG-MEB (Netherlands) on
Informational only — not a medical device.
Where it is registered
Levodopa und decarboxylasehemmer is registered in 12 of 19 countries.
Countries holding a registration under ATC N04BA02 (levodopa und decarboxylasehemmer), each read from that country’s own register.
- This record: Netherlands, from CBG-MEB (Netherlands)
- 8 of them publish a price we can compare per daily dose
Levodopa und decarboxylasehemmer · ATC N04BA02
12 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
The record
At a glance
CBG-MEB (Netherlands)- Active substance
- BENSERAZIDEHYDROCHLORIDE + LEVODOPA
- Manufacturer
- Roche Nederland B.V.
- Country
- Netherlands (NL)
- ATC code
- N04BA02
- ATC class
- Levodopa und Decarboxylasehemmer
- Reimbursed
- Not published by this register
- Source register
- CBG-MEB (Netherlands)
- Last checked
- September 29, 2026
Packs & prices · 1
- cbg_meb_id12489
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
158 interactions on record for levodopa und decarboxylasehemmer.
Graded by severity as the source publishes them — 4 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Levodopa und decarboxylasehemmer · interactions on record
158 records
- 4 severe
- 122 moderate
- 14 minor
Most severe, free to view
- ProcarbazineL01XB01severe
- OzanimodL04AA38severe
- OzanimodL04AE02severe
- Methylthioninium chlorideV03AB17severe
18 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Levodopa und decarboxylasehemmer in 12 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- SwedenLevodopa/Benserazid ratiopharm 100 mg/25 mg Tablettratiopharm GmbH
- SwitzerlandLevodopa / Benserazid Devatis 125 mg (100 mg + 25 mg), TablettenDevatis AG
- GermanyLevobensTeva Gmbh
- PolandMadoparRoche Polska Sp. z o.o.
- IcelandMadoparRoche Pharmaceuticals A/S
- FinlandAktipar 100/25Roche Oy
- FranceLEVODOPA/BENSERAZIDE TEVA 100 mg/25 mg, géluleTEVA SANTE
- NorwayMadopar 12,5/50Roche Norge AS
Authorised across Europe · EMA
The same active substance is authorised in 26 EEA countries. Names it is sold under:
- Austria · Madopar, Madopar Cr
- Belgium · Prolopa, Prolopa Hbs
- Bulgaria · Maдопар, Мадопар Hbs
- Czechia · Madopar
- Germany · Levobens, Levodopa Benserazid Beta
- Denmark · Levodopa-Benserazid Teva, Levodopa/Benserazid Orifarm
- Estonia · Madopar, Madopar Hbs
- Spain · Madopar, Madopar Retard
- Finland · Levodopa/Benserazide Orifarm, Madopar
- France · Levodopa Benserazide Teva, Lévodopa/Bensérazide Teva
- United Kingdom (Northern Ireland) · Levodopa/Benserazide Teva Uk, Madopar
- Greece · Madopar
- Croatia · Madopar
- Hungary · Madopar
- Ireland · Madopar
- Iceland · Madopar, Madopar Depot
- Italy · Madopar
- Lithuania · Madopar, Madopar Hbs
- Luxembourg · Levodopa/Benserazid Devatis, Prolopa 125
- Latvia · Madopar, Madopar Hbs
- Norway · Madopar, Madopar Depot
- Poland · Madopar, Madopar Hbs
- Portugal · Madopar, Madopar Hbs
- Romania · Madopar, Madopar Depot
- Sweden · Levodopa/Benserazid Ratiopharm, Levodopa/Benserazide Orifarm
- Slovenia · Madopar
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/fbdbe250-013f-4e57-8ed8-436692434168 GET /v1/drugs/fbdbe250-013f-4e57-8ed8-436692434168?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Capsule met gereguleerde afgifte, hard",
"route": "Oraal gebruik",
"soort": "RVG",
"source": "cbg_meb",
"smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h12489_smpc.pdf",
"strength": null,
"atc_label": "Levodopa And Decarboxylase Inhibitor",
"detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg12489",
"excipients": [
"AMMONIA (E 527)",
"CALCIUMWATERSTOFFOSFAAT 0-WATER (E 341)",
"GELATINE (E 441)",
"HYPROMELLOSE (Release controlling polymer)(E 464)",
"HYPROMELLOSE 2910 (Release controlling polymer), E4M (E 464)",
"IJZEROXIDE GEEL (E 172)",
"IJZEROXIDE ROOD (E 172)",
"INDIGOKARMIJN (E 132)",
"KALIUMHYDROXIDE (E 525)",
"MAGNESIUMSTEARAAT (E 470b)",
"MANNITOL (D-) (E 421)",
"PLANTAARDIGE OLIE, GEHYDREERD",
"POVIDON K 30 (E 1201)",
"PROPYLEENGLYCOL (E 1520)",
"RODE INKT",
"SCHELLAK (E 904)",
"TALK (E 553b)",
"TITAANDIOXIDE (E 171)"
],
"substances": [
"BENSERAZIDEHYDROCHLORIDE",
"LEVODOPA"
],
"leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h12489.pdf",
"authorised_at": "1989/04/24",
"procedure_number": null,
"dispensing_status": "Uitsluitend recept",
"registration_number": "12489",
"additional_monitoring": "N"
}See everything about levodopa und decarboxylasehemmer.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.