Poland· PL-100369920
Metcrean XR
A metformin product containing metformini hydrochloridum, registered in Poland by Synoptis Pharma Sp. z o.o.. The same ATC class is registered in 19 of our 19 countries.
Checked against URPL (Poland) on
Informational only — not a medical device.
Where it is registered
Metformin is registered in 19 of 19 countries.
Countries holding a registration under ATC A10BA02 (metformin), each read from that country’s own register.
- This record: Poland, from URPL (Poland)
- 11 of them publish a price we can compare per daily dose
Metformin · ATC A10BA02
19 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Spainprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of metformin costs, country by country.
Normalised to the WHO defined daily dose (2 g), the median price runs from $0.10 in Spain to $0.52 in Switzerland — a ×5.0 gap.
- 6 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
- US figures are pharmacy acquisition cost (CMS NADAC), not retail
Metformin · price per daily dose (2 g)
USD · FX 28 Sept 2026
- CH Switzerland$0.52
- CZ Czechia$0.24
- IT Italy$0.19
- FR France$0.17
- US United States$0.11 (acquisition cost)
- ES Spain$0.10
The record
At a glance
URPL (Poland)- Active substance
- Metformini hydrochloridum
- Manufacturer
- Synoptis Pharma Sp. z o.o.
- Country
- Poland (PL)
- ATC code
- A10BA02
- ATC class
- Metformin
- Defined daily dose
- 2 g, O
- Reimbursed
- Not published by this register
- Source register
- URPL (Poland)
- Last checked
- September 27, 2026
Packs & prices · 3
- gtin05909991415624
- gtin05909991415631
- gtin05909991415648
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
790 interactions on record for metformin.
Graded by severity as the source publishes them — 17 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Metformin · interactions on record
790 records
- 17 severe
- 353 moderate
- 45 minor
- 370 info
Most severe, free to view
- EthanolB05XX04severe
- IoxilanV08AB12severe
- CimetidineA02BA01moderate
- RanitidineA02BA02moderate
5 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Metformin in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United StatesMetforminGranules Pharmaceuticals Inc.
- CzechiaGLUCOPHAGE XRMerck Santé, Lyon
- United KingdomBolamyn SR 500mg tabletsTeva UK Ltd
- FinlandLyometStrides Nordic ApS
- ItalyGLUCOPHAGE UNIDIEBRUNO FARMACEUTICI S.P.A.
- CanadaAPO-METFORMIN ERAPOTEX INC
- NetherlandsGlucient SR 500 mg, tabletten met verlengde afgifteAll-Gen Pharmaceuticals & Generics B.V.
- SpainBROTMIN 1000 MG COMPRIMIDOS RECUBIERTOS CON PELICULA EFGMedochemie Iberia S.A.
Authorised across Europe · EMA
The same active substance is authorised in 29 EEA countries. Names it is sold under:
- Austria · Diabetex, Glucophage
- Belgium · Metformax, Metformin Activase 1000 Mg
- Bulgaria · Meglucon Xr, Metformin Interdos Pharma
- Cyprus · Brotmin, Glucophage
- Czechia · Brotmin, Glucomet
- Germany · Glucophage, Juformin
- Denmark · Forminet, Lyomet
- Estonia · Brotmin, Diabufor Xr
- Spain · Brotmin, Dianben
- Finland · Forminet, Glucophage
- France · Glimezit, Glucophage
- United Kingdom (Northern Ireland) · Abiano, Axpinet
- Greece · Glucoformin, Glucofree
- Croatia · Aglurab, Belformin
- Hungary · Adimet, Adimet Xr
- Ireland · Glucophage, Metformin Accord
- Iceland · Forminet, Glucophage
- Italy · Glucophage, Glucophage Unidie
- Lithuania · Brotmin, Metfogamma
- Luxembourg · Glucophage, Metformax
- Latvia · Brotmin, Glucient Sr
- Malta · Brotmin, Glyformin
- Netherlands · Glucient Sr, Glycofren
- Norway · Forminet, Glucophage
- Portugal · Allmet, Glucophage
- Romania · Brotmin, Glucophage
- Sweden · Forminet, Glucophage
- Slovenia · Aglurab, Glucophage
- Slovakia · Glucophage, Glucophage Xr
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of URPL (Poland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/f9f65883-2c4d-4cb2-aec4-60628feb5119 GET /v1/drugs/f9f65883-2c4d-4cb2-aec4-60628feb5119?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Tabletki o przedłużonym uwalnianiu",
"source": "urpl",
"strength": "500 mg",
"packaging": "05909991415624 ¦ Rp ¦ 127348\n30 tabl.\n05909991415631 ¦ Rp ¦ 127349\n60 tabl.\n05909991415648 ¦ Rp ¦ 127350\n90 tabl.",
"substance": "Metformini hydrochloridum 500 mg",
"common_name": "Metformini hydrochloridum",
"pl_product_id": "100369920",
"pozwolenie_nr": "25596",
"auth_procedure": "NAR",
"authorisation_validity": "2024-10-15"
}See everything about metformin.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.