United States· US:41520-304_e8df6ac2-422f-4379-89e8-4346d645fd02

care one nasal

A oxymetazoline product containing oxymetazoline hydrochloride, registered in United States by American Sales Company. The same ATC class is registered in 13 of our 19 countries.

ATC R01AA05US label

Checked against FDA National Drug Code directory (United States) on September 27, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about oxymetazoline hydrochlorideAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Oxymetazoline is registered in 13 of 19 countries.

Countries holding a registration under ATC R01AA05 (oxymetazoline), each read from that country’s own register.

This record: United States, from FDA National Drug Code directory (United States)
9 of them publish a price we can compare per daily dose

Search oxymetazoline products by name

Oxymetazoline · ATC R01AA05

13 / 19 countries

Belgiumprice
Canada
Czechiaprice
Finlandprice
Germany
Icelandprice
Ireland
Netherlands
Norwayprice
Polandprice
Spainprice
Switzerlandprice
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

FDA National Drug Code directory (United States)

Active substance: OXYMETAZOLINE HYDROCHLORIDE
Manufacturer: American Sales Company
Country: United States (US)
ATC code: R01AA05
ATC class: Oxymetazoline
Defined daily dose: 0.4 mg, N
Reimbursed: Not published by this register
Source register: FDA National Drug Code directory (United States)
Last checked: September 27, 2026

Packs & prices · 2

ndc11
41520-304-10
ndc11
4152030410
1 BOTTLE, SPRAY in 1 CARTON (41520-304-10) / 30 mL in 1 BOTTLE, SPRAY

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

58 interactions on record for oxymetazoline.

Graded by severity as the source publishes them — 7 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check oxymetazoline against other medicines How interaction checks work

Oxymetazoline · interactions on record

58 records

7 severe
48 moderate

Most severe, free to view

MethylergometrineG02AB01severe
ErgometrineG02AB03severe
DihydroergotamineN02CA01severe
ErgotamineN02CA02severe

3 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Oxymetazoline in 15 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All oxymetazoline products

Authorised across Europe · EMA

The same active substance is authorised in 28 EEA countries. Names it is sold under:

Austria · Wick Nasiben Baby Sanft, Wick Nasivin Aloe & Eukalyptus
Belgium · Nesivine, Nesivine Baby Sine Conservans
Bulgaria · Vicks Sinex Aloe And Eucalyptus, Африн
Czechia · Afrin, Afrin S Mentolem
Germany · Nasivin Erwachsene Und Schulkinder, Nasivin Für Erwachsene Und Schulkinder
Estonia · Afrin, Afrin Menthol
Spain · Antirrinum Adultos Nueva Fórmula, Cuvenax
Finland · Vicks, Vicks Sinex
France · Chlorhydrate D'oxymétazoline Eg, Pernazene
United Kingdom (Northern Ireland) · Blocked Nose Relief, Boots Decongestant
Greece · Ezixin, Ronal
Croatia · Nazopass, Operil P Za Djecu
Hungary · Afrin, Afrin Comfort Mentollal
Ireland · Vicks Sinex Micromist
Iceland · Nezeril
Italy · Equimet, Froben Raffreddore
Lithuania · Afrin, Afrin Menthol
Luxembourg · Nesivine, Nesivine Baby Sine Conservans
Latvia · Afrin, Sinex
Malta · Utabon Adults, Utabon Pediatric
Netherlands · Afrin, Afrin Met Glycerol
Norway · Rhinox
Poland · Acatar Care, Acatar Care Kids
Portugal · Alerjon, Bisolspray Nebulicina Adulto
Romania · Afrin, Afrin Mentol
Sweden · Nasin, Nezebi
Slovenia · Afrin, Nazopass
Slovakia · Afrin, Afrin S Mentolom

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/f997d7c9-d92c-4db7-9fa9-883580073694
GET /v1/drugs/f997d7c9-d92c-4db7-9fa9-883580073694?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "route": "NASAL",
  "source": "ndc",
  "strength": ".05",
  "substance": "OXYMETAZOLINE HYDROCHLORIDE",
  "productndc": "41520-304",
  "dosage_form": "SPRAY",
  "dea_schedule": null,
  "strength_unit": "g/100mL",
  "application_number": "M012",
  "marketing_category": "OTC MONOGRAPH DRUG"
}

API reference MCP server Plans

See everything about oxymetazoline.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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