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Netherlands· NL-b5906626b714

Toctino 30 mg, capsules, zacht

A alitretinoin product containing alitretinoïne, registered in Netherlands by Stiefel Laboratories Legacy (Ireland) Limited, Unit 2. The same ATC class is registered in 8 of our 19 countries.

ATC D11AH04

Checked against CBG-MEB (Netherlands) on

Informational only — not a medical device.

SOURCE REGISTER · NLCBG-MEB (Netherlands)normalisedToctino 30 mg, capsules, zachtATCD11AH04REGISTER NO.NL-b5906626b714PACKS LISTED1CHECKEDSeptember 29, 2026

Where it is registered

Alitretinoin is registered in 8 of 19 countries.

Countries holding a registration under ATC D11AH04 (alitretinoin), each read from that country’s own register.

  • This record: Netherlands, from CBG-MEB (Netherlands)
  • 5 of them publish a price we can compare per daily dose

Alitretinoin · ATC D11AH04

8 / 19 countries

  • Belgiumprice
  • Canada
  • Denmark
  • Finlandprice
  • Netherlands
  • Norwayprice
  • Switzerlandprice
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of alitretinoin costs, country by country.

Normalised to the WHO defined daily dose (20 mg), so markets compare like for like.

  • 1 market with a comparable price for this class
  • Public list prices, converted to USD at the rate date shown

Alitretinoin · price per daily dose (20 mg)

USD · FX 28 Sept 2026

  • CH Switzerland$17.29
Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

CBG-MEB (Netherlands)
Active substance
ALITRETINOÏNE
Manufacturer
Stiefel Laboratories Legacy (Ireland) Limited, Unit 2
Country
Netherlands (NL)
ATC code
D11AH04
ATC class
Alitretinoin
Defined daily dose
20 mg, O
Reimbursed
Not published by this register
Source register
CBG-MEB (Netherlands)
Last checked
September 29, 2026

Packs & prices · 1

  • cbg_meb_id
    100962

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

5 interactions on record for alitretinoin.

Graded by severity as the source publishes them — 1 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan

Alitretinoin · interactions on record

5 records

  • 1 severe
  • 4 moderate

Most severe, free to view

  • Aminolevulinic acidL01XD04severe
  • Salicylic acidD01AE12moderate
  • Porfimer sodiumL01XD01moderate
  • MethoxsalenL01XD10moderate
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Alitretinoin in 12 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All alitretinoin products

Authorised across Europe · EMA

The same active substance is authorised in 13 EEA countries. Names it is sold under:

  • Austria · Alitretan, Toctino
  • Belgium · Alitretinoin Orifarm
  • Germany · Alitrederm, Toctino
  • Denmark · Alitretinoin Orifarm, Toctino
  • Spain · Alitretinoína Ifc, Toctino
  • Finland · Alitretinoin Orifarm, Toctino
  • France · Alizem, Toctino
  • United Kingdom (Northern Ireland) · Alitretinoin Ennogen Healthcare, Alitretinoin Ennogen Ip
  • Italy · Alitrecare, Toctino
  • Norway · Alitretinoin Orifarm, Toctino
  • Portugal · Alitretinoína Cantabria
  • Sweden · Alitretinoin Orifarm
  • Slovenia · Toctino

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/f94aa970-925b-49a8-8cfe-3fe47415fc56
GET /v1/drugs/f94aa970-925b-49a8-8cfe-3fe47415fc56?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Capsule, zacht",
  "route": "Oraal gebruik",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h100962_smpc.pdf",
  "strength": null,
  "atc_label": "Alitretinoin",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg100962",
  "excipients": [
    "GELATINE (E 441)",
    "GELE OF WITTE WAS (E901)",
    "GLYCEROL (E 422)",
    "IJZEROXIDE GEEL (E 172)",
    "IJZEROXIDE ROOD  (E 172)",
    "SOJABOONOLIE, GEDEELTELIJK GEHYDREERD  (E 479b)",
    "SOJAOLIE, GEZUIVERD",
    "SORBITOL, VLOEIBAAR, NIET-KRISTALLISEERBAAR (E 420)",
    "TOCOFEROL, DL-ALFA (E 307)",
    "TRIGLYCERIDEN MIDDELLANGE KETEN",
    "WATER, GEZUIVERD"
  ],
  "substances": [
    "ALITRETINOÏNE"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h100962.pdf",
  "authorised_at": "2009/04/14",
  "procedure_number": "DK/H/1377/002",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "100962",
  "additional_monitoring": "N"
}

See everything about alitretinoin.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.