Iceland· IS-EU/1/10/637/010-013

Leflunomide medac

A leflunomide product containing leflunomidum inn, registered in Iceland by medac Gesellschaft für klinische Spezialpräparate GmbH. The same ATC class is registered in 15 of our 19 countries.

ATC L04AK01

Checked against Icelandic Medicines Agency (Iceland) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about leflunomidum innAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Leflunomide is registered in 15 of 19 countries.

Countries holding a registration under ATC L04AK01 (leflunomide), each read from that country’s own register.

This record: Iceland, from Icelandic Medicines Agency (Iceland)
9 of them publish a price we can compare per daily dose

Search leflunomide products by name

Leflunomide · ATC L04AK01

15 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Germany
Icelandprice
Italyprice
Japan
Netherlands
Norwayprice
Polandprice
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of leflunomide costs, country by country.

Normalised to the WHO defined daily dose (20 mg), the median price runs from $0.47 in United States to $2.13 in Italy — a ×4.5 gap.

3 markets with a comparable price for this class
Public list prices, converted to USD at the rate date shown
US figures are pharmacy acquisition cost (CMS NADAC), not retail

Open the full comparison — free account Drug prices for market access

Leflunomide · price per daily dose (20 mg)

USD · FX 28 Sept 2026

IT Italy$2.13
CH Switzerland$1.48
US United States$0.47 (acquisition cost)

Median listed price per WHO defined daily dose, in each market that publishes a price. US = pharmacy acquisition cost (CMS NADAC), not a retail price. Open the full comparison

The record

At a glance

Icelandic Medicines Agency (Iceland)

Active substance: Leflunomidum INN
Manufacturer: medac Gesellschaft für klinische Spezialpräparate GmbH
Country: Iceland (IS)
ATC code: L04AK01
ATC class: Leflunomide
Defined daily dose: 20 mg, O
Reimbursed: Not published by this register
Source register: Icelandic Medicines Agency (Iceland)
Last checked: September 29, 2026

Packs & prices · 0

No packs listed by the register for this record.

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

805 interactions on record for leflunomide.

Graded by severity as the source publishes them — 537 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check leflunomide against other medicines How interaction checks work

Leflunomide · interactions on record

805 records

537 severe
47 moderate
7 minor
214 info

Most severe, free to view

ClotrimazoleA01AB18severe
Chenodeoxycholic acidA05AA01severe
PrednisoloneA07EA01severe
HydrocortisoneA07EA02severe

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Leflunomide in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All leflunomide products

Authorised across Europe · EMA

The same active substance is authorised in 26 EEA countries. Names it is sold under:

Austria · Leflunomid Stada
Belgium · Leflunomid Sandoz, Leflunomide Ab
Bulgaria · Багеда
Cyprus · Arotan
Czechia · Leflon, Leflugen
Germany · Leflon, Leflunomid 1 A Pharma
Denmark · Leflunomid, Leflunomid "egis"
Estonia · Leflunomide Elvim
Spain · Lefluartil, Leflunomida Aurovitas
Finland · Leflunomide Orion, Leflunomide Stada
France · Leflunomide Arrow, Leflunomide Biogaran
United Kingdom (Northern Ireland) · Leflunomide Aspire Pharma, Leflunomide Milpharm
Greece · Lefid, Lefluonia
Hungary · Leflunomid Sandoz
Ireland · Leflunomide Aspire Pharma (Malta)
Italy · Leflunomide Aurobindo, Leflunomide Mylan
Liechtenstein · Arava, Leflunomide Medac
Lithuania · Leflunomide Elvim, Leflunomide Sandoz
Latvia · Leflunomide Elvim, Leflunomide Sandoz
Malta · Leflunomide Normon
Netherlands · Leflunomide Aurobindo, Leflunomide Cf
Norway · Arava, Leflunomide Medac
Poland · Leflunomid Bluefish, Leflunomid Egis
Portugal · Leflunomida Farmoz, Leflunomida Generis
Romania · Leflon, Leflunomidă Arena
Sweden · Leflunomid Bluefish

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Icelandic Medicines Agency (Iceland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/f68d4705-1d42-4351-81e8-b2ef009d7d5a
GET /v1/drugs/f68d4705-1d42-4351-81e8-b2ef009d7d5a?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Filmuhúðuð tafla",
  "source": "lyfjastofnun",
  "atc_raw": "L04AK01",
  "marketed": false,
  "strength": "15 mg",
  "ma_number": "EU/1/10/637/010-013",
  "substance": "Leflunomidum INN",
  "other_info": "Ávísun lyfsins er bundin við sérfræðinga í gigtarsjúkdómum.\r\nMarkaðssetning á Íslandi er háð því að Lyfjastofnun hafi staðfest að sérstök skilyrði er varða öryggi og verkun við notkun lyfsins séu uppfyllt.",
  "legal_status": "(R Z) Sérfræðingsmerkt (og lyfseðilsskylt)",
  "ma_issued_serial": "41480"
}

API reference MCP server Plans

See everything about leflunomide.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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