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Netherlands· NL-38967aede0bb

Mekinist 2 mg filmomhulde tablet

A trametinib product containing trametinibdimethylsulfoxide, registered in Netherlands by Novartis Europharm Limited. The same ATC class is registered in 12 of our 19 countries.

ATC L01EE01

Checked against CBG-MEB (Netherlands) on

Informational only — not a medical device.

SOURCE REGISTER · NLCBG-MEB (Netherlands)normalisedMekinist 2 mg filmomhulde tabletATCL01EE01REGISTER NO.NL-38967aede0bbPACKS LISTED1CHECKEDSeptember 29, 2026
Compare price across countriesPer daily dose · free accountAsk the assistant about trametinibdimethylsulfoxideAnswers with sources · free accountCheck interactionsSeverity free · mechanism on Growth

Where it is registered

Trametinib is registered in 12 of 19 countries.

Countries holding a registration under ATC L01EE01 (trametinib), each read from that country’s own register.

  • This record: Netherlands, from CBG-MEB (Netherlands)
  • 7 of them publish a price we can compare per daily dose
Search trametinib products by name

Trametinib · ATC L01EE01

12 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Icelandprice
  • Ireland
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
  • United Kingdom
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of trametinib costs, country by country.

Normalised to the WHO defined daily dose (2 mg), so markets compare like for like.

  • 1 market with a comparable price for this class
  • Public list prices, converted to USD at the rate date shown
Open the full comparison — free accountDrug prices for market access

Trametinib · price per daily dose (2 mg)

USD · FX 28 Sept 2026

  • CH Switzerland$215.55
Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

CBG-MEB (Netherlands)
Active substance
TRAMETINIBDIMETHYLSULFOXIDE
Manufacturer
Novartis Europharm Limited
Country
Netherlands (NL)
ATC code
L01EE01
ATC class
Trametinib
Defined daily dose
2 mg, O
Reimbursed
Not published by this register
Source register
CBG-MEB (Netherlands)
Last checked
September 29, 2026

Packs & prices · 1

  • cbg_meb_id
    EU/1/14/931

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

22 interactions on record for trametinib.

Graded by severity as the source publishes them — 22 moderate. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan
Check trametinib against other medicinesHow interaction checks work

Trametinib · interactions on record

22 records

  • 22 moderate

Most severe, free to view

  • FostamatinibB02BX09moderate
  • ElagolixH01CC03moderate
  • SarecyclineJ01AA14moderate
  • IsavuconazoleJ02AC05moderate
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Trametinib in 10 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All trametinib products

Authorised across Europe · EMA

The same active substance is authorised in 3 EEA countries. Names it is sold under:

  • Iceland · Mekinist, Spexotras
  • Liechtenstein · Mekinist, Spexotras
  • Norway · Mekinist, Spexotras

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/f4a8498e-dd47-4ade-af9d-69d5624678bb
GET /v1/drugs/f4a8498e-dd47-4ade-af9d-69d5624678bb?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Filmomhulde tablet",
  "route": "Oraal gebruik",
  "soort": null,
  "source": "cbg_meb",
  "smpc_url": "https://www.ema.europa.eu/en/documents/product-information/mekinist-epar-product-information_nl.pdf",
  "strength": null,
  "atc_label": "Trametinib",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/cp113393",
  "excipients": [
    "CELLULOSE, MICROKRISTALLIJN (E 460(i))",
    "CROSCARMELLOSE  NATRIUM  (E 468)",
    "HYPROMELLOSE (E 464)",
    "HYPROMELLOSE 2910 (3 - 15 mPa.s) (E 464)",
    "IJZEROXIDE ROOD  (E 172)",
    "MACROGOL 400",
    "MAGNESIUMSTEARAAT (E 470b)",
    "MANNITOL (D-) (E 421)",
    "NATRIUMLAURILSULFAAT",
    "POLYSORBAAT 80 (E 433)",
    "SILICIUMDIOXIDE (E 551)",
    "TITAANDIOXIDE (E 171)"
  ],
  "substances": [
    "TRAMETINIBDIMETHYLSULFOXIDE"
  ],
  "leaflet_url": null,
  "authorised_at": "2014/06/30",
  "procedure_number": "EMEA/H/C/002643",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "EU/1/14/931",
  "additional_monitoring": "N"
}
API referenceMCP serverPlans

See everything about trametinib.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it freeOpen in the console