Ireland· IE-PA-PA23355/059/004

Istin 10 mg hard capsule

A amlodipine product containing amlodipine besilate, registered in Ireland by Viatris Healthcare Limited. The same ATC class is registered in 18 of our 19 countries.

ATC C08CA01

Checked against HPRA (Ireland) on September 28, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about amlodipine besilateAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Amlodipine is registered in 18 of 19 countries.

Countries holding a registration under ATC C08CA01 (amlodipine), each read from that country’s own register.

This record: Ireland, from HPRA (Ireland)
11 of them publish a price we can compare per daily dose

Search amlodipine products by name

Amlodipine · ATC C08CA01

18 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Franceprice
Germany
Icelandprice
Ireland
Italyprice
Netherlands
Norwayprice
Polandprice
Spainprice
Sweden
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of amlodipine costs, country by country.

Normalised to the WHO defined daily dose (5 mg), the median price runs from $0.011 in United States to $0.49 in Switzerland — a ×47 gap.

5 markets with a comparable price for this class
Public list prices, converted to USD at the rate date shown
US figures are pharmacy acquisition cost (CMS NADAC), not retail

Open the full comparison — free account Drug prices for market access

Amlodipine · price per daily dose (5 mg)

USD · FX 28 Sept 2026

CH Switzerland$0.49
IT Italy$0.13
FR France$0.086
ES Spain$0.047
US United States$0.011 (acquisition cost)

Median listed price per WHO defined daily dose, in each market that publishes a price. US = pharmacy acquisition cost (CMS NADAC), not a retail price. Open the full comparison

The record

At a glance

HPRA (Ireland)

Active substance: Amlodipine besilate
Manufacturer: Viatris Healthcare Limited
Country: Ireland (IE)
ATC code: C08CA01
ATC class: Amlodipine
Defined daily dose: 5 mg, O
Reimbursed: Not published by this register
Source register: HPRA (Ireland)
Last checked: September 28, 2026

Packs & prices · 1

ie_pa_number
PA23355/059/004

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

402 interactions on record for amlodipine.

Graded by severity as the source publishes them — 9 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check amlodipine against other medicines How interaction checks work

Amlodipine · interactions on record

402 records

9 severe
195 moderate
2 minor
191 info

Most severe, free to view

DolasetronA04AA04severe
SimvastatinC10AA01severe
CeritinibL01ED02severe
CeritinibL01XE28severe

5 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Amlodipine in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All amlodipine products

Authorised across Europe · EMA

The same active substance is authorised in 29 EEA countries. Names it is sold under:

Austria · Amlodibene Teva, Amlodilan
Belgium · Amlodipin Ab, Amlodipin Besilaat Sandoz
Bulgaria · Nordipin 10 Mg, Nordipin 5 Mg
Cyprus · Afiten, Amlobe
Czechia · Agen, Amlodipin Teva
Germany · Amlo Besilat Tad, Amlodipin (Besilat) Dexcel
Denmark · Adipine, Amlodipin 1a Farma
Estonia · Agen, Amlocard
Spain · Amlodipino Almus, Amlodipino Alter
Finland · Amlodipin Accord, Amlodipin Krka
France · Amlodipine Almus, Amlodipine Arrow
United Kingdom (Northern Ireland) · Amlodipine, Amlodipine Accord Healthcare
Greece · Abesyl, Amilopid
Croatia · Amlodipin Genericon, Amlodipin Pharmas
Hungary · Amlobesyl, Amlodipin Sandoz
Iceland · Amló, Amlodipin Bluefish
Italy · Abis, Almidis
Lithuania · Agen, Alneta
Luxembourg · Amlodipin Besilaat Sandoz, Amlodipine Amlodipine Taw Pharma 1 mg/Ml Suspension Buvable
Latvia · Agen, Amlodipine Vitabalans
Malta · Amlodipina Ipca, Amlodipine Accord Healthcare
Netherlands · Amlober, Amlodipine (Als Besilaat) Accord
Norway · Amlodipin Accord, Amlodipin Sandoz
Poland · Adipine, Agen
Portugal · Amlocor, Amlodipina Accord
Romania · Almacor, Amlodipină Arena
Sweden · Amlodipin, Amlodipin Accord
Slovenia · Amlodipin Alkaloid-Int, Amlodipin Krka D.D.
Slovakia · Agen, Amlodipin Ratiopharm

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of HPRA (Ireland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/efd8deb7-554d-4842-8cdc-314c1d3bc64e
GET /v1/drugs/efd8deb7-554d-4842-8cdc-314c1d3bc64e?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Capsule, hard",
  "routes": [
    "Oral use"
  ],
  "source": "hpra",
  "atc_all": [
    "C08CA01"
  ],
  "strength": null,
  "pa_number": "PA23355/059/004",
  "substances": [
    "Amlodipine besilate"
  ],
  "legal_basis": "Full application (Article 8(3) of Directive No 2001/83/EC)",
  "market_info": "Not marketed",
  "authorised_at": "11/01/2019",
  "dispensing_status": "Product subject to prescription which may be renewed (B)",
  "registration_status": "AU",
  "supply_legal_status": "Supply through pharmacies only",
  "interchangeable_code": null
}

API reference MCP server Plans

See everything about amlodipine.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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