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United States· US:50242-717_59075332-49ef-4998-98c4-81e61f57d424

Cotellic

A cobimetinib product containing cobimetinib fumarate, registered in United States by Genentech, Inc.. The same ATC class is registered in 13 of our 19 countries.

ATC L01EE02

Checked against FDA National Drug Code directory (United States) on

Informational only — not a medical device.

SOURCE REGISTER · USFDA National Drug Code directory (Unite…normalisedCotellicATCL01EE02REGISTER NO.US:50242-717_59075332…PACKS LISTED1CHECKEDSeptember 27, 2026
Compare price across countriesPer daily dose · free accountAsk the assistant about cobimetinib fumarateAnswers with sources · free accountCheck interactionsSeverity free · mechanism on Growth

Where it is registered

Cobimetinib is registered in 13 of 19 countries.

Countries holding a registration under ATC L01EE02 (cobimetinib), each read from that country’s own register.

  • This record: United States, from FDA National Drug Code directory (United States)
  • 8 of them publish a price we can compare per daily dose
Search cobimetinib products by name

Cobimetinib · ATC L01EE02

13 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Icelandprice
  • Ireland
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of cobimetinib costs, country by country.

Normalised to the WHO defined daily dose (45 mg), so markets compare like for like.

  • 1 market with a comparable price for this class
  • Public list prices, converted to USD at the rate date shown
Open the full comparison — free accountDrug prices for market access

Cobimetinib · price per daily dose (45 mg)

USD · FX 28 Sept 2026

  • CH Switzerland$221.52
Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

FDA National Drug Code directory (United States)
Active substance
COBIMETINIB FUMARATE
Manufacturer
Genentech, Inc.
Country
United States (US)
ATC code
L01EE02
ATC class
Cobimetinib
Defined daily dose
45 mg, O
Reimbursed
Not published by this register
Source register
FDA National Drug Code directory (United States)
Last checked
September 27, 2026

Packs & prices · 1

  • ndc11
    50242-717-01

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

287 interactions on record for cobimetinib.

Graded by severity as the source publishes them — 110 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan
Check cobimetinib against other medicinesHow interaction checks work

Cobimetinib · interactions on record

287 records

  • 110 severe
  • 177 moderate

Most severe, free to view

  • AprepitantA04AD12severe
  • LonafarnibA16AX20severe
  • BerotralstatB06AC06severe
  • VoxelotorB06AX03severe
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Cobimetinib in 14 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All cobimetinib products

Authorised across Europe · EMA

The same active substance is authorised in 3 EEA countries. Names it is sold under:

  • Iceland · Cotellic
  • Liechtenstein · Cotellic
  • Norway · Cotellic

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/efa7f042-e61f-4415-8cdd-9a3ff2a51899
GET /v1/drugs/efa7f042-e61f-4415-8cdd-9a3ff2a51899?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "route": "ORAL",
  "source": "ndc",
  "strength": "20",
  "substance": "COBIMETINIB FUMARATE",
  "productndc": "50242-717",
  "dosage_form": "TABLET, FILM COATED",
  "dea_schedule": null,
  "strength_unit": "mg/1",
  "application_number": "NDA206192",
  "marketing_category": "NDA"
}
API referenceMCP serverPlans

See everything about cobimetinib.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it freeOpen in the console