Netherlands· NL-c9b0b18953c6
Methadon HCl Tiofarma 20 mg, tabletten
A methadone product containing methadonhydrochloride, registered in Netherlands by Tiofarma B.V.. The same ATC class is registered in 17 of our 19 countries.
Checked against CBG-MEB (Netherlands) on
Informational only — not a medical device.
Where it is registered
Methadone is registered in 17 of 19 countries.
Countries holding a registration under ATC N07BC02 (methadone), each read from that country’s own register.
- This record: Netherlands, from CBG-MEB (Netherlands)
- 9 of them publish a price we can compare per daily dose
Methadone · ATC N07BC02
17 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Icelandprice
- Ireland
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of methadone costs, country by country.
Normalised to the WHO defined daily dose (25 mg), so markets compare like for like.
- 1 market with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Methadone · price per daily dose (25 mg)
USD · FX 28 Sept 2026
- CH Switzerland$0.81
The record
At a glance
CBG-MEB (Netherlands)- Active substance
- METHADONHYDROCHLORIDE
- Manufacturer
- Tiofarma B.V.
- Country
- Netherlands (NL)
- ATC code
- N07BC02
- ATC class
- Methadone
- Defined daily dose
- 25 mg, O
- Reimbursed
- Not published by this register
- Source register
- CBG-MEB (Netherlands)
- Last checked
- September 29, 2026
Packs & prices · 1
- cbg_meb_id104281
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
433 interactions on record for methadone.
Graded by severity as the source publishes them — 153 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Methadone · interactions on record
433 records
- 153 severe
- 176 moderate
- 5 minor
- 36 info
Most severe, free to view
- PapaverineA03AD01severe
- CisaprideA03FA02severe
- OndansetronA04AA01severe
- GranisetronA04AA02severe
63 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Methadone in 17 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- SwitzerlandKetalgin
- FinlandMetadon AbcurAbcur AB
- IcelandMetadon 2care42care4 Generics ApS
- SwedenMetadon 2care4 20 mg Tablett2care4 Generics ApS
- NorwayMetadon AbcurAbcur AB
- United KingdomEptadone 1mg/ml oral solutionDee Pharmaceuticals Ltd
- United StatesDISKETSHikma Pharmaceuticals USA Inc.
- CanadaAPO-METHADONEAPOTEX INC
Authorised across Europe · EMA
The same active substance is authorised in 27 EEA countries. Names it is sold under:
- Austria · Methadon G.L., Methasan
- Belgium · Mephenon
- Bulgaria · Метадон Алкалоид, Метадон Софарма
- Czechia · Misyo, Sublana
- Germany · Methaddict, Methadon G.L. Pharma
- Denmark · Marlodon, Metadon
- Estonia · Metadon Dak
- Spain · Eptadone, Metasedin
- Finland · Dolmed, Metadon
- France · Methadone Ap-Hp, Zoryon
- United Kingdom (Northern Ireland) · Methadone, Methadone Accord Healthcare
- Greece · Methadone Ι.Φ.Ε.Τ.
- Croatia · Heptanon, Metadon Alkaloid
- Hungary · Metadon, Metadon Ep
- Ireland · Methadone Hydrochloride Alkaloid-Int, Methadone Hydrochloride Ascot Laboratories (Ireland)
- Iceland · Metadon 2care4, Metadon Abcur
- Italy · Eptadone, Metadone Cloridrato Molteni
- Lithuania · Metadon Dak
- Luxembourg · Mephenon, Methasan
- Malta · Methadone Alkaloid, Pinadone
- Norway · Metadon Abcur, Metadon Dne
- Poland · Methadone Hydrochloride Inn-Farm, Methadone Hydrochloride Molteni
- Portugal · Misyo
- Romania · Metadon Bioeel, Methasan
- Sweden · Metadon, Metadon Abcur
- Slovenia · Metadonijev Klorid Alkaloid-Int
- Slovakia · Metagla, Misyo
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/ee84f8ed-3863-4261-abf8-5e1e2b401607 GET /v1/drugs/ee84f8ed-3863-4261-abf8-5e1e2b401607?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Tablet",
"route": "Oraal gebruik",
"soort": "RVG",
"source": "cbg_meb",
"smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h104281_smpc.pdf",
"strength": null,
"atc_label": "Methadone",
"detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg104281",
"excipients": [
"CELLULOSE, MICROKRISTALLIJN (E 460(i))",
"LACTOSE 1-WATER",
"MAGNESIUMSTEARAAT (E 470b)",
"NATRIUMZETMEELGLYCOLAAT",
"SILICIUMDIOXIDE (E 551)",
"TALK (E 553b)"
],
"substances": [
"METHADONHYDROCHLORIDE"
],
"leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h104281.pdf",
"authorised_at": "2010/04/26",
"procedure_number": null,
"dispensing_status": "Uitsluitend recept",
"registration_number": "104281",
"additional_monitoring": "N"
}See everything about methadone.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.