Netherlands· NL-267c892bcce2
Pahrilan 0,5 mg filmomhulde tabletten
A riociguat product containing riociguat, registered in Netherlands by G.L. Pharma GmbH. The same ATC class is registered in 17 of our 19 countries.
Checked against CBG-MEB (Netherlands) on
Informational only — not a medical device.
Where it is registered
Riociguat is registered in 17 of 19 countries.
Countries holding a registration under ATC C02KX05 (riociguat), each read from that country’s own register.
- This record: Netherlands, from CBG-MEB (Netherlands)
- 10 of them publish a price we can compare per daily dose
Riociguat · ATC C02KX05
17 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Icelandprice
- Ireland
- Italyprice
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of riociguat costs, country by country.
Normalised to the WHO defined daily dose (4.5 mg), the median price runs from $0.056 in France to $219.06 in Switzerland — a ×3926 gap.
- 3 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Riociguat · price per daily dose (4.5 mg)
USD · FX 28 Sept 2026
- CH Switzerland$219.06
- IT Italy$147.94
- FR France$0.056
The record
At a glance
CBG-MEB (Netherlands)- Active substance
- RIOCIGUAT
- Manufacturer
- G.L. Pharma GmbH
- Country
- Netherlands (NL)
- ATC code
- C02KX05
- ATC class
- Riociguat
- Defined daily dose
- 4.5 mg, O
- Reimbursed
- Not published by this register
- Source register
- CBG-MEB (Netherlands)
- Last checked
- September 29, 2026
Packs & prices · 1
- cbg_meb_id134321
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
140 interactions on record for riociguat.
Graded by severity as the source publishes them — 10 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Riociguat · interactions on record
140 records
- 10 severe
- 103 moderate
Most severe, free to view
- DipyridamoleB01AC07severe
- DipyridamolC01DX29severe
- TheophyllinC01EB28severe
- KetoconazoleH02CA03severe
27 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Riociguat in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- FinlandAdempasBayer AG
- SwedenAdempas 0,5 mg Filmdragerad tablettBayer AG
- CzechiaADEMPASBayer AG, Leverkusen
- United StatesAdempasBayer HealthCare Pharmaceuticals Inc.
- NorwayAdempasAbacus Medicine A/S
- SwitzerlandAdempas
- IcelandAdempasBayer AG*
- IrelandAdempas 0.5 mg film-coated tabletsBayer AG
Authorised across Europe · EMA
The same active substance is authorised in 9 EEA countries. Names it is sold under:
- Austria · Pahrilan
- Cyprus · Ridecia
- Finland · Midive, Riociguat
- Greece · Ridecia, Riociguat Win Medica
- Iceland · Adempas
- Liechtenstein · Adempas
- Malta · Midive, Riociguat
- Norway · Adempas
- Sweden · Pahrilan, Ridecia
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/ee3a4407-df27-46be-ac7b-4d99fd1d3758 GET /v1/drugs/ee3a4407-df27-46be-ac7b-4d99fd1d3758?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Filmomhulde tablet",
"route": "Oraal gebruik",
"soort": "RVG",
"source": "cbg_meb",
"smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h134321_smpc.pdf",
"strength": null,
"atc_label": "Riociguat",
"detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg134321",
"excipients": [
"CALCIUMCARBONAAT (E 170)",
"CELLULOSE, MICROKRISTALLIJN (E 460(i))",
"CROSPOVIDON (E 1202)",
"HYPROMELLOSE 2910 (3 - 15 mPa.s) (E 464)",
"LACTOSE 1-WATER",
"MACROGOL 400",
"MAGNESIUMSTEARAAT (E 470b)",
"NATRIUMLAURILSULFAAT"
],
"substances": [
"RIOCIGUAT"
],
"leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h134321.pdf",
"authorised_at": "2026/06/09",
"procedure_number": "SE/H/2695/001",
"dispensing_status": "Uitsluitend recept",
"registration_number": "134321",
"additional_monitoring": "N"
}See everything about riociguat.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.