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Ireland· IE-PA-PA1405/002/002

Prolastin 4000 mg, powder and solvent for solution for infusion

A alfa1 antitrypsin product containing human alpha1-proteinase inhibitor, registered in Ireland by Grifols Deutschland GmbH. The same ATC class is registered in 11 of our 19 countries.

ATC B02AB02

Checked against HPRA (Ireland) on

Informational only — not a medical device.

SOURCE REGISTER · IEHPRA (Ireland)normalisedProlastin 4000 mg, powder and solvent…ATCB02AB02REGISTER NO.IE-PA-PA1405/002/002PACKS LISTED1CHECKEDSeptember 28, 2026

Where it is registered

Alfa1 antitrypsin is registered in 11 of 19 countries.

Countries holding a registration under ATC B02AB02 (alfa1 antitrypsin), each read from that country’s own register.

  • This record: Ireland, from HPRA (Ireland)
  • 7 of them publish a price we can compare per daily dose

Alfa1 antitrypsin · ATC B02AB02

11 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Icelandprice
  • Ireland
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of alfa1 antitrypsin costs, country by country.

Normalised to the WHO defined daily dose (0.6 g), so markets compare like for like.

  • 1 market with a comparable price for this class
  • Public list prices, converted to USD at the rate date shown

Alfa1 antitrypsin · price per daily dose (0.6 g)

USD · FX 28 Sept 2026

  • CH Switzerland$261.83
Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

HPRA (Ireland)
Active substance
Human alpha1-proteinase inhibitor
Manufacturer
Grifols Deutschland GmbH
Country
Ireland (IE)
ATC code
B02AB02
ATC class
Alfa1 antitrypsin
Defined daily dose
0.6 g, P
Reimbursed
Not published by this register
Source register
HPRA (Ireland)
Last checked
September 28, 2026

Packs & prices · 1

  • ie_pa_number
    PA1405/002/002

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Same medicine, other countries

Alfa1 antitrypsin in 12 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All alfa1 antitrypsin products

Authorised across Europe · EMA

The same active substance is authorised in 20 EEA countries. Names it is sold under:

  • Austria · Prolastin
  • Belgium · Pulmolast
  • Cyprus · Prolastina
  • Czechia · Prolastina
  • Germany · Prolastin
  • Denmark · Prolastina
  • Spain · Prolasplan, Prolastina
  • Finland · Prolastina
  • France · Alfalastin, Prolastin
  • Greece · Prolastin
  • Croatia · Prolastina
  • Iceland · Respreeza
  • Italy · Plitalfa, Prolastin
  • Liechtenstein · Respreeza
  • Netherlands · Prolastin
  • Norway · Prolastina, Respreeza
  • Poland · Prolastin, Prolastin, 4000 Mg
  • Portugal · Prolastin
  • Sweden · Prolastina
  • Slovakia · Prolastina

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of HPRA (Ireland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/edd64130-1656-48dc-ae2a-6d7b6495f421
GET /v1/drugs/edd64130-1656-48dc-ae2a-6d7b6495f421?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Powder and solvent for solution for infusion",
  "routes": [
    "Intravenous use"
  ],
  "source": "hpra",
  "atc_all": [
    "B02AB02"
  ],
  "strength": null,
  "pa_number": "PA1405/002/002",
  "substances": [
    "Human alpha1-proteinase inhibitor"
  ],
  "legal_basis": "Full application (Article 8(3) of Directive No 2001/83/EC)",
  "market_info": "Not marketed",
  "authorised_at": "13/10/2023",
  "dispensing_status": "Product subject to prescription which may not be renewed (A)",
  "registration_status": "AU",
  "supply_legal_status": "Supply through pharmacies only",
  "interchangeable_code": null
}

See everything about alfa1 antitrypsin.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.