United Kingdom· GB-APID-19696011000001100
Malarone 250mg/100mg tablets
A proguanil and atovaquone product containing proguanil + atovaquone, registered in United Kingdom by Sigma Pharmaceuticals Plc. The same ATC class is registered in 13 of our 19 countries.
Checked against NHS dm+d (United Kingdom) on
Informational only — not a medical device.
Where it is registered
Proguanil and atovaquone is registered in 13 of 19 countries.
Countries holding a registration under ATC P01BB51 (proguanil and atovaquone), each read from that country’s own register.
- This record: United Kingdom, from NHS dm+d (United Kingdom)
- 8 of them publish a price we can compare per daily dose
Proguanil and atovaquone · ATC P01BB51
13 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Icelandprice
- Ireland
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of proguanil and atovaquone costs, country by country.
Normalised to the WHO defined daily dose (0.4 g), so markets compare like for like.
- 1 market with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Proguanil and atovaquone · price per daily dose (0.4 g)
USD · FX 28 Sept 2026
- CH Switzerland$5.96
The record
At a glance
NHS dm+d (United Kingdom)- Active substance
- Proguanil + Atovaquone
- Manufacturer
- Sigma Pharmaceuticals Plc
- Country
- United Kingdom (GB)
- ATC code
- P01BB51
- ATC class
- Proguanil and atovaquone
- Defined daily dose
- 0.4 g, Proguanilhydroch
- Reimbursed
- Not published by this register
- Source register
- NHS dm+d (United Kingdom)
- Last checked
- September 13, 2026
Packs & prices · 0
No packs listed by the register for this record.
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
40 interactions on record for proguanil and atovaquone.
Graded by severity as the source publishes them — 4 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Proguanil and atovaquone · interactions on record
40 records
- 4 severe
- 27 moderate
- 3 minor
Most severe, free to view
- EfavirenzJ05AG03severe
- Sodium aurothiomalateM01CB01severe
- AuranofinM01CB03severe
- AurothioglucoseM01CB04severe
6 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Proguanil and atovaquone in 13 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United StatesAtovaquone and Proguanil HClA-S Medication Solutions
- PolandFalcimarInPharm Sp. z o.o.
- FranceATOVAQUONE/PROGUANIL BGR 250 mg/100 mg, comprimé pelliculéBIOGARAN
- NetherlandsAtovaquon/Proguanil HCl Amarox 250/100 mg, filmomhulde tablettenAmarox Pharma B.V.
- GermanyAtovaquon/Proguanilhydrochlorid AlAliud Pharma Gmbh
- FinlandAtovaquone/Proguanil Ratiopharmratiopharm GmbH
- SwitzerlandAtovaquon Plus Spirig HC
- CanadaATOVAQUONE AND PROGUANIL HYDROCHLORIDE TABLETSGLENMARK PHARMACEUTICALS CANADA INC.
Authorised across Europe · EMA
The same active substance is authorised in 25 EEA countries. Names it is sold under:
- Austria · Atovaquon/Proguanilhydrochlorid Glenmark, Atovaquon/Proguanilhydrochlorid Stada
- Belgium · Atovaquone/Proguanil Eg, Atovaquone/Proguanil Viatris
- Czechia · Malarone
- Germany · Atovaquon/Proguanilhydrochlorid Al, Atovaquon/Proguanilhydrochlorid Amarox
- Denmark · Atovaquon/Proguanilhydrochlorid Glenmark, Malarone
- Estonia · Malarone, Malarone Paediatric
- Spain · Atovacuona/Hidrocloruro De Proguanil Viatris, Malarone
- Finland · Malarone
- France · Atovaquone/Proguanil Bgr, Atovaquone/Proguanil Biogaran
- Greece · Malarone
- Hungary · Malarone
- Ireland · Atovaquone/Proguanil Hydrochloride Glenmark Arzneimittel, Atovaquone/Proguanil Hydrochloride Viatris
- Iceland · Malarone, Malastad
- Italy · Atovaquone E Proguanile Mylan Generics, Malarone
- Lithuania · Malarone
- Luxembourg · Atovaquon/Proguanilhydrochlorid Ratiopharm, Atovaquone/Proguanil Eg
- Latvia · Malarone
- Malta · Atovaquone/Proguanil Hydrochloride Amarox, Malarone
- Netherlands · Atovaquon/Proguanil Hcl Amarox, Atovaquon/Proguanil Hcl Cf
- Norway · Atovakon/Proguanil Glenmark, Malarone
- Poland · Falcimar, Malarone
- Portugal · Malarone
- Sweden · Atovaquone / Proguanil Glenmark, Malarone Junior
- Slovenia · Malarone
- Slovakia · Malarone
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of NHS dm+d (United Kingdom). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/edba4ab2-cbeb-408f-a3c3-d6bfedd80932 GET /v1/drugs/edba4ab2-cbeb-408f-a3c3-d6bfedd80932?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"apid": "19696011000001100",
"desc": "Malarone 250mg/100mg tablets (Sigma Pharmaceuticals Plc)",
"form": "Oral tablet",
"vpid": "39733311000001109",
"source": "dmd",
"vtm_id": "774693003",
"strength": "100 mg",
"substance": "Proguanil + Atovaquone",
"ingredient": "Proguanil hydrochloride",
"supplier_code": "2087601000001106"
}See everything about proguanil and atovaquone.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.