Germany· DE-A57-83c1e20aa7c78c96
Adepend
A naltrexone product containing naltrexone hydrochloride, registered in Germany by Walter Ritter Gmbh + Co. Kg. The same ATC class is registered in 16 of our 19 countries.
Checked against EMA Article 57 (European Union) on
Informational only — not a medical device.
Where it is registered
Naltrexone is registered in 16 of 19 countries.
Countries holding a registration under ATC N07BB04 (naltrexone), each read from that country’s own register.
- This record: Germany, from EMA Article 57 (European Union)
- 9 of them publish a price we can compare per daily dose
Naltrexone · ATC N07BB04
16 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of naltrexone costs, country by country.
Normalised to the WHO defined daily dose (50 mg), the median price runs from $1.04 in France to $4.34 in Switzerland — a ×4.2 gap.
- 4 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
- US figures are pharmacy acquisition cost (CMS NADAC), not retail
Naltrexone · price per daily dose (50 mg)
USD · FX 28 Sept 2026
- CH Switzerland$4.34
- IT Italy$2.06
- US United States$1.14 (acquisition cost)
- FR France$1.04
The record
At a glance
EMA Article 57 (European Union)- Active substance
- Naltrexone Hydrochloride
- Manufacturer
- Walter Ritter Gmbh + Co. Kg
- Country
- Germany (DE)
- ATC code
- N07BB04
- ATC class
- Naltrexone
- Defined daily dose
- 50 mg, O
- Reimbursed
- Not published by this register
- Source register
- EMA Article 57 (European Union)
- Last checked
- September 30, 2026
Packs & prices · 0
No packs listed by the register for this record.
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
404 interactions on record for naltrexone.
Graded by severity as the source publishes them — 42 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Naltrexone · interactions on record
404 records
- 42 severe
- 324 moderate
- 38 info
Most severe, free to view
- OpiumA07DA02severe
- MipomersenC10AX11severe
- LomitapideC10AX12severe
- BremelanotideG02CX05severe
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Naltrexone in 15 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United StatesNaltrexone HydrochlorideBryant Ranch Prepack
- United KingdomAdepend 50mg tabletspharmaand GmbH
- CzechiaADEPENDWalter Ritter GmbH & Co.KG, HAMBURG
- NorwayAdependOrpha-Devel Handels und Vertriebs GmbH
- PolandAdependWalter Ritter GmbH + Co. KG
- FinlandNaldixPOA Pharma Scandinavia AB
- SwedenNaltrexon Molteni 50 mg Filmdragerad tablettL Molteni & C Dei F.LLI Alitti Societa di Esercizio SpA
- CanadaAPO-NALTREXONEAPOTEX INC
Authorised across Europe · EMA
The same active substance is authorised in 24 EEA countries. Names it is sold under:
- Austria · Dependex, Ethylex
- Belgium · Naltrexone Accord
- Cyprus · Abernil
- Czechia · Adepend, Naltrexone Walter Ritter
- Denmark · Naltrexon "walter Ritter", Naltrexon Accord
- Estonia · Naltrexone Accord
- Spain · Tranalex
- Finland · Naldix, Naltrexon Accord
- France · Naltrexone Accord, Naltrexone Viatris
- United Kingdom (Northern Ireland) · Adepend, Naltrexone Hydrochloride Accord Healthcare
- Croatia · Adepend, Naltreksonklorid Walter Ritter
- Hungary · Adepend
- Ireland · Ethylex, Naltrexone Hydrochloride Accord Healthcare Ireland
- Italy · Antaxone, Nalorex
- Lithuania · Naltrexone Accord
- Latvia · Naltrexone Accord
- Netherlands · Naltrexon Hcl Walter Ritter, Naltrexon Hydrochloride Accord
- Norway · Naltrexone Accord, Naltrexone Poa Pharma
- Poland · Adepend, Naltex
- Portugal · Destoxican, Naltrexona Accord
- Romania · Naltrexona Amomed, Naltrexona Walter Ritter
- Sweden · Naltrexon Molteni, Naltrexon Vitaflo
- Slovenia · Adepend, Naltrekson Walter Ritter
- Slovakia · Adepend
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of EMA Article 57 (European Union). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/ec10022a-17e9-4ab3-8fef-941bd122dfc1 GET /v1/drugs/ec10022a-17e9-4ab3-8fef-941bd122dfc1?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"pzn": null,
"route": "Oral Use",
"source": "ema_art57_de",
"ma_number": null,
"substance": "Naltrexone Hydrochloride",
"atc_from_source": null,
"authorisation_country": "Germany"
}See everything about naltrexone.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.