United States· US:42227-081_421ea216-278f-4ca8-ae5d-5dafe85658a0
Cinryze
A medicinal product containing human c1-esterase inhibitor, registered in United States by Takeda Pharmaceuticals America, Inc..
Checked against FDA National Drug Code directory (United States) on
Informational only — not a medical device.
The record
At a glance
FDA National Drug Code directory (United States)- Active substance
- HUMAN C1-ESTERASE INHIBITOR
- Manufacturer
- Takeda Pharmaceuticals America, Inc.
- Country
- United States (US)
- ATC code
- —
- Reimbursed
- Not published by this register
- Source register
- FDA National Drug Code directory (United States)
- Last checked
- September 27, 2026
Packs & prices · 2
- ndc1142227081015 mL in 1 VIAL, SINGLE-USE (42227-081-01)
- ndc1142227-081-01
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Same medicine, other countries
Human c1-esterase inhibitor in 10 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- CzechiaBERINERTCSL Behring GmbH, Marburg
- United KingdomBerinert 1,500unit powder and solvent for solution for injection vialsCSL Behring UK Ltd
- SwedenBerinert 1500 IE Pulver och vätska till injektionsvätska, lösningCSL Behring GmbH
- IcelandBerinertCSL Behring GmbH*
- NorwayBerinertCSL Behring GmbH (2)
- BelgiumBerinert 2000 IUCSL Behring
- IrelandBerinert 1500 IU Powder and solvent for solution for injectionCSL Behring GmbH
- GermanyBerinertCsl Behring Gmbh
Authorised across Europe · EMA
The same active substance is authorised in 30 EEA countries. Names it is sold under:
- Austria · Berinert
- Belgium · Berinert
- Bulgaria · Беринерт
- Cyprus · Berinert
- Czechia · Berinert
- Germany · Berinert
- Denmark · Berinert
- Estonia · Berinert Iv, Berinert Sc
- Spain · Berinert
- Finland · Berinert
- France · Berinert
- United Kingdom (Northern Ireland) · Berinert
- Greece · Berinert
- Croatia · Berinert
- Hungary · Berinert
- Ireland · Berinert
- Iceland · Berinert, Cinryze
- Italy · Berinert
- Liechtenstein · Cinryze
- Lithuania · Human C1-Esterase Inhibitor Csl Behring
- Luxembourg · Berinert
- Malta · Berinert
- Netherlands · Berinert
- Norway · Berinert, Cinryze
- Poland · Berinert
- Portugal · Berinert
- Romania · Berinert
- Sweden · Berinert
- Slovenia · Berinert
- Slovakia · Berinert
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/ebfbc544-bab8-4048-b53e-a703de2f985d GET /v1/drugs/ebfbc544-bab8-4048-b53e-a703de2f985d?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"route": "INTRAVENOUS",
"source": "ndc",
"strength": "500",
"substance": "HUMAN C1-ESTERASE INHIBITOR",
"productndc": "42227-081",
"dosage_form": "INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION",
"dea_schedule": null,
"strength_unit": "[iU]/5mL",
"application_number": "BLA125267",
"marketing_category": "BLA"
}See everything about human c1-esterase inhibitor.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.