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United Kingdom· GB-APID-23046711000001104

Topotecan 4mg/4ml concentrate for solution for infusion vials

A topotecan product containing topotecan, registered in United Kingdom by Teva UK Ltd. The same ATC class is registered in 15 of our 19 countries.

ATC L01CE01

Checked against NHS dm+d (United Kingdom) on

Informational only — not a medical device.

SOURCE REGISTER · GBNHS dm+d (United Kingdom)normalisedTopotecan 4mg/4ml concentrate for sol…ATCL01CE01REGISTER NO.GB-APID-2304671100000…PACKS LISTED1CHECKEDSeptember 13, 2026

Where it is registered

Topotecan is registered in 15 of 19 countries.

Countries holding a registration under ATC L01CE01 (topotecan), each read from that country’s own register.

  • This record: United Kingdom, from NHS dm+d (United Kingdom)
  • 9 of them publish a price we can compare per daily dose

Topotecan · ATC L01CE01

15 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Germany
  • Icelandprice
  • Ireland
  • Italyprice
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of topotecan costs, country by country.

Normalised to the WHO defined daily dose (1 mg), so markets compare like for like.

  • 1 market with a comparable price for this class
  • Public list prices, converted to USD at the rate date shown

Topotecan · price per daily dose (1 mg)

USD · FX 28 Sept 2026

  • CH Switzerland$80.29
Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

NHS dm+d (United Kingdom)
Active substance
Topotecan
Manufacturer
Teva UK Ltd
Country
United Kingdom (GB)
ATC code
L01CE01
ATC class
Topotecan
Defined daily dose
1 mg, O
Reimbursed
Not published by this register
Source register
NHS dm+d (United Kingdom)
Last checked
September 13, 2026

Packs & prices · 1

  • gtin
    5017007081012

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

348 interactions on record for topotecan.

Graded by severity as the source publishes them — 31 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan

Topotecan · interactions on record

348 records

  • 31 severe
  • 277 moderate
  • 16 minor
  • 24 info

Most severe, free to view

  • CisplatinL01XA01severe
  • CarboplatinL01XA02severe
  • OxaliplatinL01XA03severe
  • RolapitantA04AD14moderate
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Topotecan in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All topotecan products

Authorised across Europe · EMA

The same active substance is authorised in 29 EEA countries. Names it is sold under:

  • Austria · Topotecan Accord, Topotecan Ebewe
  • Belgium · Topotecan Accord Healthcare
  • Bulgaria · Топотекан Акорд
  • Cyprus · Topotecan Accord, Topotecan Venus
  • Czechia · Topotecan Accord
  • Germany · Topotecan Accord, Topotecan Hexal
  • Denmark · Topotecan "ebewe", Topotecan Accord
  • Estonia · Topotecan Accord
  • Spain · Topotecán Accord
  • Finland · Topotecan Accord, Topotecan Ebewe
  • France · Topotecane Accord
  • Greece · Topocan, Topotecan Accord
  • Croatia · Topotekan Alpha-Medical
  • Hungary · Topotecan Accord
  • Ireland · Topotecan Accord
  • Iceland · Hycamtin, Potactasol
  • Italy · Topotecan Ahcl
  • Liechtenstein · Hycamtin, Hycamtin 4 Mg Powder For Concentrate For Solution For Infusion
  • Lithuania · Topotecan Accord
  • Luxembourg · Topotecan Accord Healthcare
  • Latvia · Topotecan Ahcl
  • Netherlands · Topotecan Accord, Topotecan Hikma
  • Norway · Hycamtin, Potactasol
  • Poland · Topotecanum Accord
  • Portugal · Topotecano Accord, Topotecano Azevedos
  • Romania · Topotecan Accord
  • Sweden · Topotecan Accord, Topotecan Ebewe
  • Slovenia · Topotekan Accord
  • Slovakia · Topotecan Accord

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of NHS dm+d (United Kingdom). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/e9188ef0-fbe9-4461-b649-e0c19de7dd62
GET /v1/drugs/e9188ef0-fbe9-4461-b649-e0c19de7dd62?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "apid": "23046711000001104",
  "desc": "Topotecan 4mg/4ml concentrate for solution for infusion vials (Teva UK Ltd)",
  "form": "Solution for infusion",
  "vpid": "19627511000001104",
  "source": "dmd",
  "vtm_id": "777809000",
  "strength": "1 mg",
  "substance": "Topotecan",
  "ingredient": "Topotecan hydrochloride",
  "supplier_code": "3849901000001105"
}

See everything about topotecan.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.