Switzerland· 62452001

Palexia retard 50 mg, Retardtabletten

A tapentadol product containing tapentadolum, registered in Switzerland by Grünenthal Pharma AG and dispensed under Swissmedic category A+, on the national reimbursement list. The same ATC class is registered in 17 of our 19 countries.

Reimbursed in Switzerland (BAG SL)Cat A+ (Swissmedic)ATC N02AX06

Checked against Swissmedic (Switzerland) on September 12, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about tapentadolumAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Tapentadol is registered in 17 of 19 countries.

Countries holding a registration under ATC N02AX06 (tapentadol), each read from that country’s own register.

This record: Switzerland, from Swissmedic (Switzerland)
10 of them publish a price we can compare per daily dose

Search tapentadol products by name

Tapentadol · ATC N02AX06

17 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Germany
Icelandprice
Ireland
Italyprice
Netherlands
Norwayprice
Polandprice
Spainprice
Sweden
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of tapentadol costs, country by country.

Normalised to the WHO defined daily dose (0.4 g), the median price runs from $2.14 in Italy to $6.62 in Switzerland — a ×3.1 gap.

Switzerland: $6.62 per daily dose (median across products in the class)
Public list prices, converted to USD at the rate date shown

Open the full comparison — free account Drug prices for market access

Tapentadol · price per daily dose (0.4 g)

USD · FX 28 Sept 2026

CH Switzerland$6.62
ES Spain$3.34
IT Italy$2.14

Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

Swissmedic (Switzerland)

Active substance: tapentadolum
Manufacturer: Grünenthal Pharma AG
Country: Switzerland (CH)
ATC code: N02AX06
ATC class: Tapentadol
Defined daily dose: 0.4 g, O
Swissmedic category: A+
Reimbursed: Yes
Source register: Swissmedic (Switzerland)
Last checked: September 12, 2026

Packs & prices · 1

1 priced

gtin
7680624520011
30 Stk
CHF 33.75

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

184 interactions on record for tapentadol.

Graded by severity as the source publishes them — 30 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check tapentadol against other medicines How interaction checks work

Tapentadol · interactions on record

184 records

30 severe
130 moderate

Most severe, free to view

OndansetronA04AA01severe
GranisetronA04AA02severe
DolasetronA04AA04severe
PalonosetronA04AA05severe

24 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Tapentadol in 15 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All tapentadol products

Authorised across Europe · EMA

The same active substance is authorised in 25 EEA countries. Names it is sold under:

Austria · Palexia, Palexia Retard
Belgium · Palexia, Palexia Retard
Cyprus · Dolten, Dolten Retard
Czechia · Apeneta, Dolupren
Germany · Palexia, Palexia Akutschmerz
Denmark · Palexia, Palexia Depot
Estonia · Tapemed Retard
Spain · Palexia, Palexia Retard
United Kingdom (Northern Ireland) · Ationdo, Ationdo Sr
Greece · Dolupren, Dolupren Ir
Croatia · Apeneta, Dolten
Hungary · Adoben
Ireland · Apeneta, Palexia
Iceland · Tapentadol Stada
Italy · Palexia, Taboxea
Luxembourg · Palexia, Palexia Retard
Malta · Dolten, Dolten Retard
Netherlands · Palexia, Palexia Retard
Norway · Palexia, Palexia Depot
Poland · Adoben, Binatta
Portugal · Ationdo, Palexia
Romania · Dolten
Sweden · Palexia, Palexia Depot
Slovenia · Apeneta, Palexia
Slovakia · Apeneta, Dolten

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Swissmedic (Switzerland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/e8ca073c-86f7-490c-b429-b73db12729b3
GET /v1/drugs/e8ca073c-86f7-490c-b429-b73db12729b3?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "unit": null,
  "strength": "tapentadolum 50 mg",
  "valid_from": "2014-02-01",
  "limitations": null,
  "galenic_form": "Ret Tabl 50 mg",
  "therapeutic_area": null,
  "sl_inclusion_date": "2014-02-01",
  "self_retention_pct": 10
}

API reference MCP server Plans

See everything about tapentadol.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it free Open in the console