United States· US:70518-3922_3ba3881f-2be9-c6fc-e063-6394a90a452d

Estradiol

A estradiol product containing estradiol, registered in United States by REMEDYREPACK INC.. The same ATC class is registered in 13 of our 19 countries.

ATC G03CA03Orange BookUS label

Checked against FDA National Drug Code directory (United States) on

Informational only — not a medical device.

SOURCE REGISTER · USFDA National Drug Code directory (Unite…normalisedEstradiolATCG03CA03REGISTER NO.US:70518-3922_3ba3881…PACKS LISTED2CHECKEDSeptember 12, 2026

Where it is registered

Estradiol is registered in 13 of 19 countries.

Countries holding a registration under ATC G03CA03 (estradiol), each read from that country’s own register.

  • This record: United States, from FDA National Drug Code directory (United States)
  • 9 of them publish a price we can compare per daily dose

Estradiol · ATC G03CA03

13 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Icelandprice
  • Ireland
  • Italyprice
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of estradiol costs, country by country.

Normalised to the WHO defined daily dose (0.3 mg), so markets compare like for like.

  • 1 market with a comparable price for this class
  • Public list prices, converted to USD at the rate date shown

Estradiol · price per daily dose (0.3 mg)

USD · FX 28 Sept 2026

  • CH Switzerland$0.11
Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

FDA National Drug Code directory (United States)
Active substance
Estradiol
Manufacturer
REMEDYREPACK INC.
Country
United States (US)
ATC code
G03CA03
ATC class
Estradiol
Defined daily dose
0.3 mg, N
Reimbursed
Not published by this register
Source register
FDA National Drug Code directory (United States)
Last checked
September 12, 2026

Packs & prices · 2

  • ndc11
    7051839220
    30 TABLET in 1 BLISTER PACK (70518-3922-0)
  • ndc11
    7051839221
    90 TABLET in 1 BOTTLE, PLASTIC (70518-3922-1)

Regulatory notes

UNII (FDA substance ID)
4TI98Z838E
ESTRADIOL
RxCUI 4083
Orange Book
A217334
ABABAB
DailyMed SPL labels
1 version tracked

Interactions

328 interactions on record for estradiol.

Graded by severity as the source publishes them — 7 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan

Estradiol · interactions on record

328 records

  • 7 severe
  • 177 moderate
  • 3 minor
  • 131 info

Most severe, free to view

  • Tranexamic acidB02AA02severe
  • HeminB06AB01severe
  • CarfilzomibL01XG02severe
  • CarfilzomibL01XX45severe

10 more interactions with mechanism and management, from a commercially licensed source.

Sign in to check
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Estradiol in 17 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All estradiol products

Authorised across Europe · EMA

The same active substance is authorised in 30 EEA countries. Names it is sold under:

  • Austria · Estrofem, Femseven
  • Belgium · Estradiol Besins, Estrofem
  • Bulgaria · Естрогел, Естрофем
  • Cyprus · Vagifem
  • Czechia · Estradiol Besins, Estrofem
  • Germany · Estradiol Fem Jenapharm, Estrifam
  • Denmark · Divigel, Ercostrol
  • Estonia · Divigel, Estradiol Besins
  • Spain · Divigel, Estradiol Besins
  • Finland · Divigel, Estradot
  • France · Dermestril, Dermestril Septem
  • United Kingdom (Northern Ireland) · Elleste, Elleste Solo Mx
  • Greece · Vagifem
  • Croatia · Estradiol Besins, Estrofem
  • Hungary · Estradiol Besins, Estrofem
  • Ireland · Divigel, Estradiol Sun
  • Iceland · Estring, Estrofem
  • Italy · Dermestril, Femseven
  • Lithuania · Divigel, Estradiol Besins
  • Luxembourg · Dermestril 100, Dermestril 25
  • Latvia · Estradiol Besins, Estrofem
  • Malta · Oestrogel Pump-Pack, Vagifem
  • Netherlands · Cetura, Estradiol Sandoz
  • Norway · Estradot, Estrogel
  • Poland · Divigel, Estrofem
  • Portugal · Dermestril, Estradot
  • Romania · Estradiol Besins
  • Sweden · Divigel, Estradiol Besins
  • Slovenia · Estradiol Besins, Vagifem
  • Slovakia · Estradiol Besins, Estrofem

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/e872412b-2b72-49a3-a258-17208ac19186
GET /v1/drugs/e872412b-2b72-49a3-a258-17208ac19186?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "unii": {
    "unii": "4TI98Z838E",
    "rxcui": "4083",
    "inchikey": "VOXZDWNPVJITMN-ZBRFXRBCSA-N",
    "display_name": "ESTRADIOL",
    "substance_type": "chemical",
    "ingredient_type": "INGREDIENT SUBSTANCE"
  },
  "route": "ORAL",
  "livertox": {
    "summary": null,
    "livertox_id": null,
    "hepatotoxicity_score": 1
  },
  "spl_meta": {
    "50c786d6-91bd-4eea-9455-ff2abc08372f": {
      "match": "brand_token",
      "title": "ESTRADIOL AND NORETHINDRONE ACETATE TABLET [INGENUS PHARMACEUTICALS, LLC]",
      "spl_version": "5",
      "published_date": "2026-06-01"
    }
  },
  "productid": "70518-3922_3ba3881f-2be9-c6fc-e063-6394a90a452d",
  "productndc": "70518-3922",
  "dosage_form": "TABLET",
  "orange_book": {
    "appl_no": "217334",
    "products": [
      {
        "rs": false,
        "rld": false,
        "te_code": "AB",
        "strength": "0.5MG",
        "product_no": "001",
        "approval_date": "Sep 6, 2023"
      },
      {
        "rs": false,
        "rld": false,
        "te_code": "AB",
        "strength": "1MG",
        "product_no": "002",
        "approval_date": "Sep 6, 2023"
      },
      {
        "rs": false,
        "rld": false,
        "te_code": "AB",
        "strength": "2MG",
        "product_no": "003",
        "approval_date": "Sep 6, 2023"
      }
    ],
    "appl_type": "A"
  },
  "dea_schedule": null,
  "product_type": "HUMAN PRESCRIPTION DRUG",
  "substance_name": "ESTRADIOL",
  "proprietary_name": "Estradiol",
  "active_ingred_unit": "mg/1",
  "application_number": "ANDA217334",
  "marketing_category": "ANDA",
  "nonproprietary_name": "Estradiol",
  "start_marketing_date": "20231122",
  "active_numerator_strength": "1"
}

See everything about estradiol.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.