United States· US:70518-3922_3ba3881f-2be9-c6fc-e063-6394a90a452d
Estradiol
A estradiol product containing estradiol, registered in United States by REMEDYREPACK INC.. The same ATC class is registered in 13 of our 19 countries.
Checked against FDA National Drug Code directory (United States) on
Informational only — not a medical device.
Where it is registered
Estradiol is registered in 13 of 19 countries.
Countries holding a registration under ATC G03CA03 (estradiol), each read from that country’s own register.
- This record: United States, from FDA National Drug Code directory (United States)
- 9 of them publish a price we can compare per daily dose
Estradiol · ATC G03CA03
13 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Icelandprice
- Ireland
- Italyprice
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
- United Statesprice
Price per daily dose
What a daily dose of estradiol costs, country by country.
Normalised to the WHO defined daily dose (0.3 mg), so markets compare like for like.
- 1 market with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Estradiol · price per daily dose (0.3 mg)
USD · FX 28 Sept 2026
- CH Switzerland$0.11
The record
At a glance
FDA National Drug Code directory (United States)- Active substance
- Estradiol
- Manufacturer
- REMEDYREPACK INC.
- Country
- United States (US)
- ATC code
- G03CA03
- ATC class
- Estradiol
- Defined daily dose
- 0.3 mg, N
- Reimbursed
- Not published by this register
- Source register
- FDA National Drug Code directory (United States)
- Last checked
- September 12, 2026
Packs & prices · 2
- ndc11705183922030 TABLET in 1 BLISTER PACK (70518-3922-0)
- ndc11705183922190 TABLET in 1 BOTTLE, PLASTIC (70518-3922-1)
Regulatory notes
Interactions
328 interactions on record for estradiol.
Graded by severity as the source publishes them — 7 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Estradiol · interactions on record
328 records
- 7 severe
- 177 moderate
- 3 minor
- 131 info
Most severe, free to view
- Tranexamic acidB02AA02severe
- HeminB06AB01severe
- CarfilzomibL01XG02severe
- CarfilzomibL01XX45severe
10 more interactions with mechanism and management, from a commercially licensed source.
Sign in to check- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Estradiol in 17 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United KingdomClimaval 1mg tabletsNecessity Supplies Ltd
- CanadaLUPIN-ESTRADIOLLUPIN PHARMA CANADA LIMITED
- IcelandFemanestExeltis Healthcare S.L.*
- NorwayProgynovaBayer
- SwedenDivigel 0,5 mg GelOrion Corporation
- SwitzerlandDivigel
- NetherlandsCetura 0,5 mg tablettenACE Pharmaceuticals B.V.
- PolandDivigel 0,1%InPharm Sp. z o.o.
Authorised across Europe · EMA
The same active substance is authorised in 30 EEA countries. Names it is sold under:
- Austria · Estrofem, Femseven
- Belgium · Estradiol Besins, Estrofem
- Bulgaria · Естрогел, Естрофем
- Cyprus · Vagifem
- Czechia · Estradiol Besins, Estrofem
- Germany · Estradiol Fem Jenapharm, Estrifam
- Denmark · Divigel, Ercostrol
- Estonia · Divigel, Estradiol Besins
- Spain · Divigel, Estradiol Besins
- Finland · Divigel, Estradot
- France · Dermestril, Dermestril Septem
- United Kingdom (Northern Ireland) · Elleste, Elleste Solo Mx
- Greece · Vagifem
- Croatia · Estradiol Besins, Estrofem
- Hungary · Estradiol Besins, Estrofem
- Ireland · Divigel, Estradiol Sun
- Iceland · Estring, Estrofem
- Italy · Dermestril, Femseven
- Lithuania · Divigel, Estradiol Besins
- Luxembourg · Dermestril 100, Dermestril 25
- Latvia · Estradiol Besins, Estrofem
- Malta · Oestrogel Pump-Pack, Vagifem
- Netherlands · Cetura, Estradiol Sandoz
- Norway · Estradot, Estrogel
- Poland · Divigel, Estrofem
- Portugal · Dermestril, Estradot
- Romania · Estradiol Besins
- Sweden · Divigel, Estradiol Besins
- Slovenia · Estradiol Besins, Vagifem
- Slovakia · Estradiol Besins, Estrofem
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/e872412b-2b72-49a3-a258-17208ac19186 GET /v1/drugs/e872412b-2b72-49a3-a258-17208ac19186?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"unii": {
"unii": "4TI98Z838E",
"rxcui": "4083",
"inchikey": "VOXZDWNPVJITMN-ZBRFXRBCSA-N",
"display_name": "ESTRADIOL",
"substance_type": "chemical",
"ingredient_type": "INGREDIENT SUBSTANCE"
},
"route": "ORAL",
"livertox": {
"summary": null,
"livertox_id": null,
"hepatotoxicity_score": 1
},
"spl_meta": {
"50c786d6-91bd-4eea-9455-ff2abc08372f": {
"match": "brand_token",
"title": "ESTRADIOL AND NORETHINDRONE ACETATE TABLET [INGENUS PHARMACEUTICALS, LLC]",
"spl_version": "5",
"published_date": "2026-06-01"
}
},
"productid": "70518-3922_3ba3881f-2be9-c6fc-e063-6394a90a452d",
"productndc": "70518-3922",
"dosage_form": "TABLET",
"orange_book": {
"appl_no": "217334",
"products": [
{
"rs": false,
"rld": false,
"te_code": "AB",
"strength": "0.5MG",
"product_no": "001",
"approval_date": "Sep 6, 2023"
},
{
"rs": false,
"rld": false,
"te_code": "AB",
"strength": "1MG",
"product_no": "002",
"approval_date": "Sep 6, 2023"
},
{
"rs": false,
"rld": false,
"te_code": "AB",
"strength": "2MG",
"product_no": "003",
"approval_date": "Sep 6, 2023"
}
],
"appl_type": "A"
},
"dea_schedule": null,
"product_type": "HUMAN PRESCRIPTION DRUG",
"substance_name": "ESTRADIOL",
"proprietary_name": "Estradiol",
"active_ingred_unit": "mg/1",
"application_number": "ANDA217334",
"marketing_category": "ANDA",
"nonproprietary_name": "Estradiol",
"start_marketing_date": "20231122",
"active_numerator_strength": "1"
}See everything about estradiol.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.