Netherlands· NL-8817e1929e8b

Hopledo 350 mg/87,5 mg harde capsules met gereguleerde afgifte

A levodopa und decarboxylasehemmer product containing carbidopa 1-water + levodopa, registered in Netherlands by Zambon S.p.A.. The same ATC class is registered in 12 of our 19 countries.

ATC N04BA02

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about carbidopa 1-water + levodopaAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Levodopa und decarboxylasehemmer is registered in 12 of 19 countries.

Countries holding a registration under ATC N04BA02 (levodopa und decarboxylasehemmer), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
8 of them publish a price we can compare per daily dose

Search levodopa und decarboxylasehemmer products by name

Levodopa und decarboxylasehemmer · ATC N04BA02

12 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Icelandprice
Ireland
Italyprice
Netherlands
Norwayprice
Polandprice
Switzerlandprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

CBG-MEB (Netherlands)

Active substance: CARBIDOPA 1-WATER + LEVODOPA
Manufacturer: Zambon S.p.A.
Country: Netherlands (NL)
ATC code: N04BA02
ATC class: Levodopa und Decarboxylasehemmer
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
EU/1/26/2054

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

158 interactions on record for levodopa und decarboxylasehemmer.

Graded by severity as the source publishes them — 4 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check levodopa und decarboxylasehemmer against other medicines How interaction checks work

Levodopa und decarboxylasehemmer · interactions on record

158 records

4 severe
122 moderate
14 minor

Most severe, free to view

ProcarbazineL01XB01severe
OzanimodL04AA38severe
OzanimodL04AE02severe
Methylthioninium chlorideV03AB17severe

18 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Levodopa und decarboxylasehemmer in 9 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All levodopa und decarboxylasehemmer products

Authorised across Europe · EMA

The same active substance is authorised in 29 EEA countries. Names it is sold under:

Austria · Duodopa
Belgium · Duodopa, Precifit
Bulgaria · Дуодопа, Синепар
Cyprus · Duodopa
Czechia · Duodopa, Isicom
Germany · Duodopa, Isicom
Denmark · Carbidopa/Levodopa Fair-Med, Levodopa/Carbidopa Teva
Estonia · Duodopa
Spain · Carbidopa/Levodopa Aurovitas, Carbidopa/Levodopa Kern Pharma
Finland · Duodopa
France · Levodopa Carbidopa Teva
United Kingdom (Northern Ireland) · Carbidopa/Levodopa Milpharm, Co-Careldopa
Greece · Duodopa
Croatia · Duodopa
Hungary · Duodopa
Ireland · Carbidopa/Levodopa Fair-Med, Duodopa
Iceland · Duodopa
Italy · Carbidopa E Levodopa Aurobindo, Duodopa
Liechtenstein · Duodopa
Lithuania · Duodopa, Levodopa/Carbidopa Fairmed
Luxembourg · Duodopa, Precifit
Latvia · Duodopa
Norway · Carbidopa/Levodopa Fair-Med, Duodopa
Poland · Precifit
Portugal · Duodopa, Levodopa + Carbidopa Generis
Romania · Duodopa, Isicom
Sweden · Carbidopa/Levodopa Fair-Med, Duodopa
Slovenia · Duodopa
Slovakia · Duodopa, Isicom

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/e75c5bf6-2e96-4d0f-b3f6-55d0e2833daf
GET /v1/drugs/e75c5bf6-2e96-4d0f-b3f6-55d0e2833daf?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Capsule met gereguleerde afgifte, hard",
  "route": "Oraal gebruik",
  "soort": null,
  "source": "cbg_meb",
  "smpc_url": "https://www.ema.europa.eu/en/documents/product-information/hopledo-epar-product-information_nl.pdf",
  "strength": null,
  "atc_label": "Levodopa And Decarboxylase Inhibitor",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/cp135428",
  "excipients": [
    "AMMONIA (E 527)",
    "BASISCH GEBUTYLEERD METHACRYLAAT COPOLYMEER (E 1205)",
    "CELLULOSE, MICROKRISTALLIJN (E 460(i))",
    "CELLULOSEACETAAT",
    "COPOLYMEER VAN METHACRYLZUUR-METHYLMETHACRYLAAT (1:1)",
    "COPOVIDON (E 1208)",
    "CROSCARMELLOSE  NATRIUM  (E 468)",
    "GELATINE (E 441)",
    "IJZEROXIDE GEEL (E 172)",
    "IJZEROXIDE ROOD  (E 172)",
    "IJZEROXIDE ZWART (E 172)",
    "MAGNESIUMSTEARAAT (E 470b)",
    "MANNITOL (D-) (E 421)",
    "NATRIUMHYDROXIDE (E 524)",
    "NATRIUMLAURILSULFAAT",
    "POVIDON (E 1201)",
    "POVIDON K 30 (E 1201)",
    "PROPYLEENGLYCOL (E 1520)",
    "PROPYLEENGLYCOL (E 1520)",
    "SCHELLAK (E 904)",
    "SCHELLAK GLAZE, GEDEELTELIJK VERESTERD",
    "TALK (E 553b)",
    "TITAANDIOXIDE (E 171)",
    "TITAANDIOXIDE (E 171)",
    "TRIETHYLCITRAAT (E 1505)",
    "WITTE INKT",
    "ZWARTE INKT"
  ],
  "substances": [
    "CARBIDOPA 1-WATER",
    "LEVODOPA"
  ],
  "leaflet_url": null,
  "authorised_at": "2026/08/20",
  "procedure_number": "EMEA/H/C/006629",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "EU/1/26/2054",
  "additional_monitoring": "N"
}

API reference MCP server Plans

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This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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