Canada· CA-DIN-02530406
RYLAZE
A asparaginase product containing crisantaspase, registered in Canada by JAZZ PHARMACEUTICALS IRELAND LIMITED. The same ATC class is registered in 15 of our 19 countries.
Checked against Health Canada Drug Product Database (Canada) on
Informational only — not a medical device.
Where it is registered
Asparaginase is registered in 15 of 19 countries.
Countries holding a registration under ATC L01XX02 (asparaginase), each read from that country’s own register.
- This record: Canada, from Health Canada Drug Product Database (Canada)
- 9 of them publish a price we can compare per daily dose
Asparaginase · ATC L01XX02
15 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Icelandprice
- Ireland
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
- United Kingdom
- United Statesprice
The record
At a glance
Health Canada Drug Product Database (Canada)- Active substance
- CRISANTASPASE
- Manufacturer
- JAZZ PHARMACEUTICALS IRELAND LIMITED
- Country
- Canada (CA)
- ATC code
- L01XX02
- ATC class
- Asparaginase
- Reimbursed
- Not published by this register
- Source register
- Health Canada Drug Product Database (Canada)
- Last checked
- October 1, 2026
Packs & prices · 0
No packs listed by the register for this record.
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
280 interactions on record for asparaginase.
Graded by severity as the source publishes them — 7 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Asparaginase · interactions on record
280 records
- 7 severe
- 273 moderate
Most severe, free to view
- ClotrimazoleA01AB18moderate
- Chenodeoxycholic acidA05AA01moderate
- PrednisoloneA07EA01moderate
- HydrocortisoneA07EA02moderate
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Asparaginase in 14 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- IrelandEnrylaze 10 mg/0.5 mL solution for injection/infusion.Jazz Pharmaceuticals Ireland Limited
- SpainENRYLAZE 10 MG/0,5 ML, SOLUCION INYECTABLE Y PARA PERFUSIONJazz Pharmaceuticals Ireland Limited
- NetherlandsEnrylaze 10 mg/0,5 ml oplossing voor injectie/infusieJazz Pharmaceuticals Ireland Ltd.
- NorwayErwinasePorton Biopharma Limided
- PolandEnrylazeJazz Pharmaceuticals Ireland Ltd
- BelgiumEnrylaze 10 mg/0.5 mlJazz Pharmaceuticals Ireland
- FranceENRYLAZE 10 mg/0,5 mL, solution injectable/pour perfusionJAZZ PHARMACEUTICALS IRELAND LIMITED (IRLANDE)
- GermanyErwinasePorton Biopharma Limited
Authorised across Europe · EMA
The same active substance is authorised in 12 EEA countries. Names it is sold under:
- Belgium · Erwinase
- Germany · Erwinase
- Denmark · Erwinase
- Spain · Erwinase
- Finland · Erwinase
- France · Erwinase
- United Kingdom (Northern Ireland) · Erwinase
- Ireland · Erwinase
- Netherlands · Erwinase
- Norway · Erwinase
- Portugal · Erwinase
- Sweden · Erwinase
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Health Canada Drug Product Database (Canada). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/e6da6e4d-77e9-4ed3-a2a7-f0148c7f50f7 GET /v1/drugs/e6da6e4d-77e9-4ed3-a2a7-f0148c7f50f7?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"din": "02530406",
"form": "SOLUTION",
"class": "Human",
"routes": [
"INTRAMUSCULAR"
],
"source": "health_canada_dpd",
"status": "MARKETED",
"atc_raw": "L01XX02",
"schedule": [
"Prescription",
"Schedule D"
],
"drug_code": "101958",
"strengths": [
"10 MG"
],
"ahfs_class": null,
"substances": [
"CRISANTASPASE"
],
"product_categorization": null
}See everything about asparaginase.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.