Poland· PL-100327784

Prothromplex Total NF

A coagulation factor ix, ii, vii and x in combination product containing prothrombinum multiplex humanum, registered in Poland by Takeda Pharma Sp. z o.o.. The same ATC class is registered in 11 of our 19 countries.

ATC B02BD01

Checked against URPL (Poland) on September 27, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about prothrombinum multiplex humanumAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Coagulation factor ix, ii, vii and x in combination is registered in 11 of 19 countries.

Countries holding a registration under ATC B02BD01 (coagulation factor ix, ii, vii and x in combination), each read from that country’s own register.

This record: Poland, from URPL (Poland)
7 of them publish a price we can compare per daily dose

Search coagulation factor ix, ii, vii and x in combination products by name

Coagulation factor ix, ii, vii and x in combination · ATC B02BD01

11 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Icelandprice
Ireland
Netherlands
Norwayprice
Polandprice
Switzerlandprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

URPL (Poland)

Active substance: Prothrombinum multiplex humanum
Manufacturer: Takeda Pharma Sp. z o.o.
Country: Poland (PL)
ATC code: B02BD01
ATC class: Coagulation factor IX, II, VII and X in combination
Defined daily dose: 1.6 TSD, E
Reimbursed: Not published by this register
Source register: URPL (Poland)
Last checked: September 27, 2026

Packs & prices · 5

gtin
05909991196448
gtin
05909991237318
gtin
05909991237332
gtin
05909991237349
gtin
05909991237356

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

3 interactions on record for coagulation factor ix, ii, vii and x in combination.

Graded by severity as the source publishes them — 2 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check coagulation factor ix, ii, vii and x in combination against other medicines How interaction checks work

Coagulation factor ix, ii, vii and x in combination · interactions on record

3 records

2 severe
1 moderate

Most severe, free to view

CarfilzomibL01XG02severe
CarfilzomibL01XX45severe
PegvaliaseA16AB19moderate

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Coagulation factor ix, ii, vii and x in combination in 1 other country

What each register calls a product with the same active substance — salts and hydrates count as the same.

All coagulation factor ix, ii, vii and x in combination products

CzechiaBERIPLEXCSL Behring GmbH, Marburg

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of URPL (Poland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/e3795967-9e85-492c-a35f-e11524ed8069
GET /v1/drugs/e3795967-9e85-492c-a35f-e11524ed8069?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Proszek i rozpuszczalnik do sporządzania roztworu do wstrzykiwań",
  "source": "urpl",
  "strength": "600 j.m.",
  "packaging": "05909991196448 ¦ Rp ¦ 104969\n1 fiol.  proszku ¦ 1 fiol. 20 ml rozp. ¦ 1 igła  z filtrem ¦ 1 igła  z odpowietrznikiem ¦ 1 igła  dwustronna\n05909991237318 ¦ Rp ¦ 110794\n1 fiol.  proszku ¦ 1 igła  z filtrem ¦ 1 igła  z odpowietrznikiem ¦ 1 strzyk.  jednorazowa ¦ 1 fiol. 20 ml rozp. ¦ 1 igła  motylkowa ¦ 1 igła  jednorazowa ¦ 1 igła  dwustronna\n05909991237332 ¦ Rp ¦ 110796\n1 fiol.  proszku ¦ 1 igła  z filtrem ¦ 1 igła  motylkowa ¦ 1 igła  jednorazowa ¦ 1 fiol. 20 ml rozp. ¦ 1 igła  z odpowietrznikiem ¦ 1 igła  dwustronna\n05909991237349 ¦ Rp ¦ 110797\n1 fiol.  proszku ¦ 1 igła  dwustronna ¦ 1 igła  jednorazowa ¦ 1 igła  z odpowietrznikiem ¦ 1 igła  motylkowa ¦ 1 igła  z filtrem ¦ 1 fiol. 20 ml rozp.\n05909991237356 ¦ Rp ¦ 110798\n1 fiol.  proszku ¦ 1 igła  jednorazowa ¦ 1 igła  z filtrem ¦ 1 igła  jednorazowa ¦ 1 igła  motylkowa ¦ 1 igła  z odpowietrznikiem ¦ 1 igła  dwustronna ¦ 1 fiol. 20 ml rozp.",
  "substance": "Ludzki czynnik krzepnięcia II 480 - 900 j.m./fiol. + Ludzki czynnik krzepnięcia VII 500 j.m./fiol. + Ludzki czynnik krzepnięcia IX 600 j.m./fiol. + Ludzki czynnik krzepnięcia X 600 j.m./fiol. + Białko C 400 j.m./fiol.",
  "common_name": "Prothrombinum multiplex humanum",
  "pl_product_id": "100327784",
  "pozwolenie_nr": "22169",
  "auth_procedure": "MRP",
  "authorisation_validity": "Bezterminowe"
}

API reference MCP server Plans

See everything about coagulation factor ix, ii, vii and x in combination.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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