Netherlands· NL-0c312c9833fd

Sacubitril/Valsartan Pluspharma 97 mg/103 mg filmomhulde tabletten

A valsartan and sacubitril product containing sacubitril natrium + valsartan dinatrium, registered in Netherlands by +pharma arzneimittel gmbh. The same ATC class is registered in 15 of our 19 countries.

ATC C09DX04

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about sacubitril natrium + valsartan dinatriumAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Valsartan and sacubitril is registered in 15 of 19 countries.

Countries holding a registration under ATC C09DX04 (valsartan and sacubitril), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
9 of them publish a price we can compare per daily dose

Search valsartan and sacubitril products by name

Valsartan and sacubitril · ATC C09DX04

15 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Icelandprice
Ireland
Italyprice
Japan
Netherlands
Norwayprice
Polandprice
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

CBG-MEB (Netherlands)

Active substance: SACUBITRIL NATRIUM + VALSARTAN DINATRIUM
Manufacturer: +pharma arzneimittel gmbh
Country: Netherlands (NL)
ATC code: C09DX04
ATC class: Valsartan and sacubitril
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
134481

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

8 interactions on record for valsartan and sacubitril.

Graded by severity as the source publishes them — 8 moderate. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check valsartan and sacubitril against other medicines How interaction checks work

Valsartan and sacubitril · interactions on record

8 records

8 moderate

Most severe, free to view

NitisinoneA16AX04moderate
SimvastatinC10AA01moderate
RosuvastatinC10AA07moderate
Darunavir and cobicistatJ05AR14moderate

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Valsartan and sacubitril in 13 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All valsartan and sacubitril products

Authorised across Europe · EMA

The same active substance is authorised in 30 EEA countries. Names it is sold under:

Austria · Sabivalsax, Sacubitril/Valsartan Devatis
Belgium · Sacubitril/Valsartan Eg, Sacubitril/Valsartan Hcs
Bulgaria · Атрилесто, Валкубит
Cyprus · Sacubitril/Valsartan Accord, Sacubitril/Valsartan Tad
Czechia · Sacubitril/Valsartan Accord, Sacubitril/Valsartan Polpharma
Germany · Sacubitril/Valsartan Accord, Sacubitril/Valsartan Al
Denmark · Bitrisal, Lumivaxon
Estonia · Culbista, Sacubitril/Valsartan Accord
Spain · Bidcor, Sacubitrilo / Valsartán Cinfamed
Finland · Lumivaxon, Sacubitril/Valsartan Accord
France · Sacubitril / Valsartan Biogaran, Sacubitril/Valsartan Accord
United Kingdom (Northern Ireland) · Sacubitril/Valsartan, Sacubitril/Valsartan Stada
Greece · Bitrisal, Ensavalia
Croatia · Atrilesto, Culbista
Hungary · Sacubitril/Valsartan Gedeon Richter, Sacubitril/Valsartan Stada
Ireland · Sacubitril/Valsartan Accord, Sacubitril/Valsartan Krka
Iceland · Entresto, Neparvis
Italy · Sacubitril E Valsartan Accord, Sacubitril E Valsartan Alter
Liechtenstein · Entresto, Neparvis
Lithuania · Culbista, Sacubitril/Valsartan Polpharma
Luxembourg · Sacubitril/Valsartan Eg
Latvia · Culbista, Sacubitril/Valsartan Gedeon Richter
Malta · Sacubitril/Valsartan Axunio, Sacubitril/Valsartan Clonmel
Norway · Entresto, Neparvis
Poland · Brazier, Culbista
Portugal · Bidcor, Neprilin
Romania · Sacubitril/Valsartan Dr. Reddy’s, Sacubitril/Valsartan Gedeon Richter
Sweden · Sacubitril/Valsartan Accord, Sacubitril/Valsartan Axunio
Slovenia · Sakubitril/Valsartan Galenika, Sakubitril/Valsartan Hcs
Slovakia · Sacubitril/Valsartan Gedeon Richter, Sacubitril/Valsartan Polpharma

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/e361e83f-6c34-4b7e-ab63-43e497baffbd
GET /v1/drugs/e361e83f-6c34-4b7e-ab63-43e497baffbd?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Filmomhulde tablet",
  "route": "Oraal gebruik",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h134481_smpc_en.pdf",
  "strength": null,
  "atc_label": "Valsartan and sacubitril",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg134481",
  "excipients": [
    "CELLULOSE, MICROKRISTALLIJN (E 460(i))",
    "CROSPOVIDON (E 1202)",
    "HYDROXYPROPYLCELLULOSE, LAAG GESUBSTITUEERD (E 463a)",
    "HYPROMELLOSE 2910 (3 - 15 mPa.s) (E 464)",
    "IJZEROXIDE ROOD  (E 172)",
    "IJZEROXIDE ZWART (E 172)",
    "MACROGOL 4000",
    "MAGNESIUMSTEARAAT (E 470b)",
    "MANNITOL (D-) (E 421)",
    "SILICIUMDIOXIDE, GEHYDRATEERD (E 551)",
    "TALK (E 553b)",
    "TITAANDIOXIDE (E 171)"
  ],
  "substances": [
    "SACUBITRIL NATRIUM",
    "VALSARTAN DINATRIUM"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h134481_piluk.pdf",
  "authorised_at": "2025/10/20",
  "procedure_number": "NL/H/6323/003",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "134481",
  "additional_monitoring": "N"
}

API reference MCP server Plans

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This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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