Netherlands· NL-e0c776ad6e77

Lachgas Messer 100% v/v medicinaal gas, vloeibaar gemaakt

A nitrous oxide product containing distikstofoxide (e 942), registered in Netherlands by Messer Belgium N.V.. The same ATC class is registered in 12 of our 19 countries.

ATC N01AX13

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about distikstofoxide (e 942)Answers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Nitrous oxide is registered in 12 of 19 countries.

Countries holding a registration under ATC N01AX13 (nitrous oxide), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
8 of them publish a price we can compare per daily dose

Search nitrous oxide products by name

Nitrous oxide · ATC N01AX13

12 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Icelandprice
Ireland
Netherlands
Norwayprice
Polandprice
Switzerlandprice
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

CBG-MEB (Netherlands)

Active substance: DISTIKSTOFOXIDE (E 942)
Manufacturer: Messer Belgium N.V.
Country: Netherlands (NL)
ATC code: N01AX13
ATC class: Nitrous oxide
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
111763

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

9 interactions on record for nitrous oxide.

Graded by severity as the source publishes them — 3 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check nitrous oxide against other medicines How interaction checks work

Nitrous oxide · interactions on record

9 records

3 severe
6 moderate

Most severe, free to view

MethotrexateL01BA01severe
MethotrexateL04AX03severe
MethotrexatM01CX01severe
OpiumA07DA02moderate

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Nitrous oxide in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All nitrous oxide products

Authorised across Europe · EMA

The same active substance is authorised in 29 EEA countries. Names it is sold under:

Austria · Distickstoffmonoxid Westfalen, Stickoxydul Medizinisch
Belgium · Dinitrox, Distickstoff Oxid Air Products
Bulgaria · Nitrous Oxide Messer 100%, Медицински Диазотен Оксид Sol
Cyprus · Medicinal Nitrous Oxide Linde- Hadjikyriakos Gas Ltd
Czechia · Medicinální Oxid Dusný, Medicinální Oxid Dusný Messer
Germany · Distickstoffmonoxid Air Products, Distickstoffmonoxid Für Medizinische Zwecke Nippon Gases Deutschland
Denmark · Medicinsk Dinitrogenoxid Air Liquide, Medicinsk Dinitrogenoxid Nippon Gases Scandinavia
Estonia · Dilämmastikoksiid, Niontix
Spain · Óxido Nitroso, Oxido Nitroso Medicinal Air Liquide
Finland · Lääkkeellinen Ilokaasu Awo, Niontix
France · Protoxyde D'azote Medicinal, Protoxyde D'azote Medicinal Air Liquide Sante France
United Kingdom (Northern Ireland) · Medical Nitrous Oxide Boc, Nitrous Oxide
Greece · Niontix, Φαρμακευτικό Πρωτοξείδιο Του Αζώτου Sol
Croatia · Dušični Oksidul Utp, Dušikov(I) Oksid Messer
Hungary · Dinitrogén-Oxid Air Products, Dinitrogén-Oxid Bus-Oxy
Ireland · Medical Nitrous Oxide Boc Gases Ireland, Nitrous Oxide Medicinal Sol
Iceland · Lyfjatvíköfnunarefnisoxíð Strandmøllen, Niontix
Italy · Alfaprot, Azoto Protossido Air Liquide Sanità
Lithuania · Diazoto Oksidas Elme Messer Gaas, Diazoto Oksidas Gaschema
Luxembourg · Niontix, Protoxyde D'azote Médical Air Liquide Santé International
Latvia · Mediciniskais Slapekla Oksiduls, Saskidrinatais, Niontix
Malta · Medical Nitrous Oxide Boc Gases Ireland
Norway · Medisinsk Lystgass, Medisinsk Lystgass Nippon Gases Scandinavia
Poland · Podtlenek Azotu, Podtlenek Azotu Air Products
Portugal · Niontix, Protóxido De Azoto
Romania · Niontix, Protoxid De Azot Medicinal Siad
Sweden · Medicinsk Lustgas Air Liquide, Medicinsk Lustgas Nippon Gases Scandinavia
Slovenia · Medicinski Didušikov Oksid Istrabenz Plini, Medicinski Didusikov Oksid Messer
Slovakia · Medicinálny Oxid Dusný Siad, Medicinálny Oxid Dusný Sol

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/e2eb8d95-dde4-4c98-921e-313a560dc377
GET /v1/drugs/e2eb8d95-dde4-4c98-921e-313a560dc377?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Medicinaal gas, vloeibaar gemaakt",
  "route": "Inhalatie",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h111763_smpc.pdf",
  "strength": null,
  "atc_label": "Nitrous Oxide",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg111763",
  "excipients": [
    "GEEN HULPSTOFFEN"
  ],
  "substances": [
    "DISTIKSTOFOXIDE (E 942)"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h111763.pdf",
  "authorised_at": "2013/04/16",
  "procedure_number": "NL/H/2606/001",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "111763",
  "additional_monitoring": "N"
}

API reference MCP server Plans

See everything about nitrous oxide.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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