Canada· CA-DIN-02370468
SAMSCA
A tolvaptan product containing tolvaptan, registered in Canada by OTSUKA PHARMACEUTICAL CO LTD. The same ATC class is registered in 13 of our 19 countries.
Checked against Health Canada Drug Product Database (Canada) on
Informational only — not a medical device.
Where it is registered
Tolvaptan is registered in 13 of 19 countries.
Countries holding a registration under ATC C03XA01 (tolvaptan), each read from that country’s own register.
- This record: Canada, from Health Canada Drug Product Database (Canada)
- 8 of them publish a price we can compare per daily dose
Tolvaptan · ATC C03XA01
13 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Icelandprice
- Ireland
- Italyprice
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Switzerlandprice
Price per daily dose
What a daily dose of tolvaptan costs, country by country.
Normalised to the WHO defined daily dose (30 mg), the median price runs from $1.82 in Czechia to $127.86 in Italy — a ×70 gap.
- 4 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Tolvaptan · price per daily dose (30 mg)
USD · FX 28 Sept 2026
- IT Italy$127.86
- CH Switzerland$72.80
- FR France$14.28
- CZ Czechia$1.82
The record
At a glance
Health Canada Drug Product Database (Canada)- Active substance
- TOLVAPTAN
- Manufacturer
- OTSUKA PHARMACEUTICAL CO LTD
- Country
- Canada (CA)
- ATC code
- C03XA01
- ATC class
- Tolvaptan
- Defined daily dose
- 30 mg, O
- Reimbursed
- Not published by this register
- Source register
- Health Canada Drug Product Database (Canada)
- Last checked
- October 1, 2026
Packs & prices · 0
No packs listed by the register for this record.
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
183 interactions on record for tolvaptan.
Graded by severity as the source publishes them — 16 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Tolvaptan · interactions on record
183 records
- 16 severe
- 161 moderate
- 6 minor
Most severe, free to view
- KetoconazoleH02CA03severe
- ClarithromycinJ01FA09severe
- KetoconazoleJ02AB02severe
- Darunavir and cobicistatJ05AR14severe
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same medicine, other countries
Tolvaptan in 16 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United StatesJYNARQUEOtsuka America Pharmaceutical, Inc.
- SpainJINARC 15 mg + 45 mg COMPRIMIDOSOtsuka Pharmaceutical Netherlands B.V.
- IcelandGurdatolSandoz A/S
- SwedenJinarc 15 mg TablettOtsuka Pharmaceutical Netherlands B.V.
- CzechiaJINARCOtsuka Pharmaceutical Netherlands B.V., Amsterdam
- NorwayJinarcOtsuka Pharmaceutical Netherlands B.V.
- FranceJINARC 15 mg, compriméOTSUKA PHARMACEUTICAL NETHERLANDS (PAYS BAS)
- United KingdomJinarc 15mg tabletsOtsuka Pharmaceuticals (U.K.) Ltd
Authorised across Europe · EMA
The same active substance is authorised in 21 EEA countries. Names it is sold under:
- Austria · Tolvaptan, Tolvaptan +pharma
- Belgium · Tolvaptan, Tolvaptan Eg
- Czechia · Tolvaptan Stada
- Germany · Tolvaptan, Tolvaptan 1 A Pharma
- Estonia · Tolvaptan Stada
- Spain · Tolvaptán Sandoz, Tolvaptan Stadafarma
- France · Tolvaptan Biogaran, Tolvaptan Eg
- United Kingdom (Northern Ireland) · Tolvaptan, Tolvaptan Genus Pharmaceuticals
- Greece · Gurdatol, Pokydy
- Croatia · Gurdatol
- Ireland · Tolvaptan Ascend
- Iceland · Gurdatol, Jinarc
- Italy · Tolvaptan Teva, Tolvaptan Teva Italia
- Liechtenstein · Jinarc, Samsca
- Lithuania · Tolvaptan Stada
- Latvia · Tolvaptan Stada
- Netherlands · Tolvaptan Sandoz, Tolvaptan Teva
- Norway · Jinarc, Samsca
- Poland · Tolvaptan Sandoz
- Portugal · Tolvaptano Stada, Tolvaptano Stada 15 Mg + 45 Mg Comprimidos
- Sweden · Tolvaptan Hexal, Tolvaptan Sandoz
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Health Canada Drug Product Database (Canada). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/e245537b-d68a-4ced-a037-154525a774ec GET /v1/drugs/e245537b-d68a-4ced-a037-154525a774ec?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"din": "02370468",
"form": "TABLET",
"class": "Human",
"routes": [
"ORAL"
],
"source": "health_canada_dpd",
"status": "MARKETED",
"atc_raw": "C03XA01",
"schedule": [
"Prescription"
],
"drug_code": "85561",
"strengths": [
"15 MG"
],
"ahfs_class": null,
"substances": [
"TOLVAPTAN"
],
"product_categorization": null
}See everything about tolvaptan.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.