United States· US:72789-009_560798a8-34ca-25ac-e063-6294a90ad854

METFORMIN HYDROCHLORIDE EXTENDED RELEASE

A metformin product containing metformin hydrochloride, registered in United States by PD-Rx Pharmaceuticals, Inc.. The same ATC class is registered in 19 of our 19 countries.

ATC A10BA02

Checked against FDA National Drug Code directory (United States) on September 27, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about metformin hydrochlorideAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Metformin is registered in 19 of 19 countries.

Countries holding a registration under ATC A10BA02 (metformin), each read from that country’s own register.

This record: United States, from FDA National Drug Code directory (United States)
11 of them publish a price we can compare per daily dose

Search metformin products by name

Metformin · ATC A10BA02

19 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Franceprice
Germany
Icelandprice
Ireland
Italyprice
Japan
Netherlands
Norwayprice
Polandprice
Spainprice
Sweden
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of metformin costs, country by country.

Normalised to the WHO defined daily dose (2 g), the median price runs from $0.10 in Spain to $0.52 in Switzerland — a ×5.0 gap.

United States: $0.11 per daily dose (median across products in the class)
Public list prices, converted to USD at the rate date shown
US figures are pharmacy acquisition cost (CMS NADAC), not retail

Open the full comparison — free account Drug prices for market access

Metformin · price per daily dose (2 g)

USD · FX 28 Sept 2026

CH Switzerland$0.52
CZ Czechia$0.24
IT Italy$0.19
FR France$0.17
US United States$0.11 (acquisition cost)
ES Spain$0.10

Median listed price per WHO defined daily dose, in each market that publishes a price. US = pharmacy acquisition cost (CMS NADAC), not a retail price. Open the full comparison

The record

At a glance

FDA National Drug Code directory (United States)

Active substance: METFORMIN HYDROCHLORIDE
Manufacturer: PD-Rx Pharmaceuticals, Inc.
Country: United States (US)
ATC code: A10BA02
ATC class: Metformin
Defined daily dose: 2 g, O
Reimbursed: Not published by this register
Source register: FDA National Drug Code directory (United States)
Last checked: September 27, 2026

Packs & prices · 4

ndc11
72789-009-30
ndc11
72789-009-60
ndc11
72789-009-90
ndc11
72789-009-93

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

790 interactions on record for metformin.

Graded by severity as the source publishes them — 17 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check metformin against other medicines How interaction checks work

Metformin · interactions on record

790 records

17 severe
353 moderate
45 minor
370 info

Most severe, free to view

EthanolB05XX04severe
IoxilanV08AB12severe
CimetidineA02BA01moderate
RanitidineA02BA02moderate

5 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Metformin in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All metformin products

Authorised across Europe · EMA

The same active substance is authorised in 30 EEA countries. Names it is sold under:

Austria · Diabetex, Glucophage
Belgium · Metformax, Metformin Activase 1000 Mg
Bulgaria · Meglucon Xr, Metformin Interdos Pharma
Cyprus · Brotmin, Glucophage
Czechia · Brotmin, Glucomet
Germany · Glucophage, Juformin
Denmark · Forminet, Lyomet
Estonia · Brotmin, Diabufor Xr
Spain · Brotmin, Dianben
Finland · Forminet, Glucophage
France · Glimezit, Glucophage
United Kingdom (Northern Ireland) · Abiano, Axpinet
Greece · Glucoformin, Glucofree
Croatia · Aglurab, Belformin
Hungary · Adimet, Adimet Xr
Ireland · Glucophage, Metformin Accord
Iceland · Forminet, Glucophage
Italy · Glucophage, Glucophage Unidie
Lithuania · Brotmin, Metfogamma
Luxembourg · Glucophage, Metformax
Latvia · Brotmin, Glucient Sr
Malta · Brotmin, Glyformin
Netherlands · Glucient Sr, Glycofren
Norway · Forminet, Glucophage
Poland · Abmetfina Xr, Avamina
Portugal · Allmet, Glucophage
Romania · Brotmin, Glucophage
Sweden · Forminet, Glucophage
Slovenia · Aglurab, Glucophage
Slovakia · Glucophage, Glucophage Xr

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/e16641f1-8803-44d5-8e0b-88ef4bb6c959
GET /v1/drugs/e16641f1-8803-44d5-8e0b-88ef4bb6c959?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "route": "ORAL",
  "source": "ndc",
  "strength": "500",
  "substance": "METFORMIN HYDROCHLORIDE",
  "productndc": "72789-009",
  "dosage_form": "TABLET, EXTENDED RELEASE",
  "dea_schedule": null,
  "strength_unit": "mg/1",
  "application_number": "ANDA090295",
  "marketing_category": "ANDA"
}

API reference MCP server Plans

See everything about metformin.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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