Netherlands· NL-55d67f3e33e4

Puri-Nethol, 50 mg tabletten

A mercaptopurine product containing mercaptopurine 1-water, registered in Netherlands by Originalis B.V.. The same ATC class is registered in 17 of our 19 countries.

ATC L01BB02

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about mercaptopurine 1-waterAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Mercaptopurine is registered in 17 of 19 countries.

Countries holding a registration under ATC L01BB02 (mercaptopurine), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
10 of them publish a price we can compare per daily dose

Search mercaptopurine products by name

Mercaptopurine · ATC L01BB02

17 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Franceprice
Germany
Icelandprice
Ireland
Italyprice
Netherlands
Norwayprice
Polandprice
Sweden
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of mercaptopurine costs, country by country.

Normalised to the WHO defined daily dose (0.175 g), the median price runs from $2.01 in France to $13.99 in Switzerland — a ×6.9 gap.

3 markets with a comparable price for this class
Public list prices, converted to USD at the rate date shown

Open the full comparison — free account Drug prices for market access

Mercaptopurine · price per daily dose (0.175 g)

USD · FX 28 Sept 2026

CH Switzerland$13.99
IT Italy$5.09
FR France$2.01

Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

CBG-MEB (Netherlands)

Active substance: MERCAPTOPURINE 1-WATER
Manufacturer: Originalis B.V.
Country: Netherlands (NL)
ATC code: L01BB02
ATC class: Mercaptopurine
Defined daily dose: 0.175 g, O
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
125552//00859

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

324 interactions on record for mercaptopurine.

Graded by severity as the source publishes them — 38 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check mercaptopurine against other medicines How interaction checks work

Mercaptopurine · interactions on record

324 records

38 severe
117 moderate
18 minor
147 info

Most severe, free to view

MipomersenC10AX11severe
LomitapideC10AX12severe
RibavirinJ05AB04severe
RibavirinJ05AP01severe

4 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Mercaptopurine in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All mercaptopurine products

Authorised across Europe · EMA

The same active substance is authorised in 24 EEA countries. Names it is sold under:

Austria · Mercaptopurin Silver, Puri-Nethol
Belgium · Puri-Nethol
Bulgaria · Пури-Нетол
Czechia · Merkaptopurin Avmc, Puri-Nethol
Germany · Medipurin, Mercaptopurin-Medice
Denmark · Mercaptopurine Accord, Mercaptopurine Silver Pharma
Estonia · Puri-Nethol
Spain · Mercaptopurina, Mercaptopurina Qualix
Finland · Mercaptopurin Orion, Purimmun
France · Purinethol
United Kingdom (Northern Ireland) · Hanixol, Mercaptopurine Accord-Uk
Ireland · Mercaptopurine Silver Pharma, Puri-Nethol
Iceland · Puri-Nethol, Purimmun
Italy · Purinethol
Lithuania · Puri-Nethol
Luxembourg · Puri-Nethol
Malta · Puri-Nethol
Norway · Mercaptopurine Accord, Merkaptopurin Silver
Poland · Mercaptopurinum Vis
Portugal · Mercaptopurina Accord, Mercaptopurina Silver
Romania · Mercaptopurină Accord, Puri-Nethol
Sweden · Mercaptopurine Accord, Mercaptopurine Silver
Slovenia · Puri-Nethol
Slovakia · Puri-Nethol

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/e11f7031-6b9f-49bf-880b-b19fe1ac5198
GET /v1/drugs/e11f7031-6b9f-49bf-880b-b19fe1ac5198?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Tablet",
  "route": "Oraal gebruik",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h00859_smpc.pdf",
  "strength": null,
  "atc_label": "Mercaptopurine",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg125552",
  "excipients": [
    "LACTOSE 0-WATER",
    "MAGNESIUMSTEARAAT (E 470b)",
    "MAÏSZETMEEL",
    "MAÏSZETMEEL, GEHYDROLYSEERD",
    "STEARINEZUUR (E 570)"
  ],
  "substances": [
    "MERCAPTOPURINE 1-WATER"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h125552.pdf",
  "authorised_at": "2019/09/16",
  "procedure_number": null,
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "125552//00859",
  "additional_monitoring": "N"
}

API reference MCP server Plans

See everything about mercaptopurine.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

Try it free Open in the console