Ireland· IE-PA-EU/1/98/082/001
COMTESS 200 mg Film-coated tablet
A entacapone product, registered in Ireland by Orion Corporation. The same ATC class is registered in 18 of our 19 countries.
Checked against HPRA (Ireland) on
Informational only — not a medical device.
Where it is registered
Entacapone is registered in 18 of 19 countries.
Countries holding a registration under ATC N04BX02 (entacapone), each read from that country’s own register.
- This record: Ireland, from HPRA (Ireland)
- 10 of them publish a price we can compare per daily dose
Entacapone · ATC N04BX02
18 / 19 countries
- Belgiumprice
- Canada
- Czechiaprice
- Denmark
- Finlandprice
- Franceprice
- Germany
- Icelandprice
- Ireland
- Italyprice
- Japan
- Netherlands
- Norwayprice
- Polandprice
- Sweden
- Switzerlandprice
- United Kingdom
- United Statesprice
Price per daily dose
What a daily dose of entacapone costs, country by country.
Normalised to the WHO defined daily dose (1 g), the median price runs from $1.87 in France to $6.60 in Switzerland — a ×3.5 gap.
- 3 markets with a comparable price for this class
- Public list prices, converted to USD at the rate date shown
Entacapone · price per daily dose (1 g)
USD · FX 28 Sept 2026
- CH Switzerland$6.60
- IT Italy$6.27
- FR France$1.87
The record
At a glance
HPRA (Ireland)- Manufacturer
- Orion Corporation
- Country
- Ireland (IE)
- ATC code
- N04BX02
- ATC class
- Entacapone
- Defined daily dose
- 1 g, O
- Reimbursed
- Not published by this register
- Source register
- HPRA (Ireland)
- Last checked
- September 28, 2026
Packs & prices · 1
- ie_pa_numberEU/1/98/082/001
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Interactions
110 interactions on record for entacapone.
Graded by severity as the source publishes them — 2 severe. Severity grades are free for everyone; mechanism and management come with Growth.
- Severity for every pair — free, no plan needed
- The source, licence and sync date on every record
- Mechanism and what to do for each pair — Growth plan
Entacapone · interactions on record
110 records
- 2 severe
- 61 moderate
- 1 minor
- 46 info
Most severe, free to view
- ProcarbazineL01XB01severe
- Methylthioninium chlorideV03AB17severe
- EpinephrineA01AD01moderate
- MetoclopramideA03FA01moderate
- Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Same class
Other records under N04BX02
Entacapone, as other registers publish it.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of HPRA (Ireland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/df812765-7203-4463-8795-89a52214ec50 GET /v1/drugs/df812765-7203-4463-8795-89a52214ec50?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"form": "Tablet",
"routes": null,
"source": "hpra",
"atc_all": [
"N04BX",
"N04BX02"
],
"strength": null,
"pa_number": "EU/1/98/082/001",
"substances": null,
"legal_basis": "Full application (Article 8(3) of Directive No 2001/83/EC)",
"market_info": "Unknown",
"authorised_at": null,
"dispensing_status": "Product subject to prescription which may be renewed (B)",
"registration_status": "AU",
"supply_legal_status": "Supply through pharmacies only",
"interchangeable_code": null
}See everything about entacapone.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.