Italy· 023177138

NAPROSYN

A naproxen product containing naprossene, registered in Italy by RECORDATI INDUSTRIA CHIMICA FARMACEUTICA S.P.A., on the national reimbursement list. The same ATC class is registered in 15 of our 19 countries.

Reimbursed in Italy (AIFA class A)ATC M01AE02

Checked against AIFA (Italy) on

Informational only — not a medical device.

SOURCE REGISTER · ITAIFA (Italy)normalisedNAPROSYNATCM01AE02REGISTER NO.023177138PACKS LISTED1CHECKEDSeptember 28, 2026

Where it is registered

Naproxen is registered in 15 of 19 countries.

Countries holding a registration under ATC M01AE02 (naproxen), each read from that country’s own register.

  • This record: Italy, from AIFA (Italy)
  • 9 of them publish a price we can compare per daily dose

Naproxen · ATC M01AE02

15 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Germany
  • Icelandprice
  • Ireland
  • Italyprice
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of naproxen costs, country by country.

Normalised to the WHO defined daily dose (0.5 g), the median price runs from $0.16 in Italy to $0.82 in Switzerland — a ×4.9 gap.

  • Italy: $0.16 per daily dose (median across products in the class)
  • Public list prices, converted to USD at the rate date shown

Naproxen · price per daily dose (0.5 g)

USD · FX 28 Sept 2026

  • CH Switzerland$0.82
  • IT Italy$0.16
Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

AIFA (Italy)
Active substance
Naprossene
Manufacturer
RECORDATI INDUSTRIA CHIMICA FARMACEUTICA S.P.A.
Country
Italy (IT)
ATC code
M01AE02
ATC class
Naproxen
Defined daily dose
0.5 g, O
Reimbursed
Yes
Source register
AIFA (Italy)
Last checked
September 28, 2026

Packs & prices · 1

1 priced
  • aic
    023177138
    "500 MG GRANULATO" 30 BUSTINE
    EUR 4.78

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

495 interactions on record for naproxen.

Graded by severity as the source publishes them — 58 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan

Naproxen · interactions on record

495 records

  • 58 severe
  • 176 moderate
  • 17 minor
  • 161 info

Most severe, free to view

  • DicoumarolB01AA01severe
  • WarfarinB01AA03severe
  • DalteparinB01AB04severe
  • EnoxaparinB01AB05severe

83 more interactions with mechanism and management, from a commercially licensed source.

Sign in to check
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Naproxen in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All naproxen products

Authorised across Europe · EMA

The same active substance is authorised in 29 EEA countries. Names it is sold under:

  • Austria · Aleve, Miranax
  • Belgium · Aleve, Apranax
  • Bulgaria · Налгезин, Налгезин Форте
  • Cyprus · Naprorex, Priaxen
  • Czechia · Emoxen, Nalgesin
  • Germany · Aspidolo, Dolormin Für Frauen Bei Menstruationsbeschwerden Mit
  • Denmark · Bonyl, Naproxen Evolan
  • Estonia · Emox, Nalgesin Forte
  • Spain · Actromadol, Antalgin
  • Finland · Miranax, Naprometin
  • France · Aleve, Alevetabs
  • United Kingdom (Northern Ireland) · Almus Period Pain Reliever, Boots Period Pain Reliever
  • Greece · Anaprox, Naprosyn
  • Croatia · Nalgesin, Nalgesin Forte
  • Hungary · Aleve, Aleve Extra
  • Ireland · Naprosyn Ec, Naproxen Azure Pharmaceuticals
  • Iceland · Naproxen Viatris, Naproxen-E Viatris
  • Lithuania · Emox, Nalgesin Forte
  • Luxembourg · Aleve, Apranax
  • Latvia · Emox, Nalgedol
  • Malta · Naprorex, Naprosyn
  • Netherlands · Aleve Classic Bij Pijn En Koorts, Aleve Feminax Bij Menstruatiepijn
  • Norway · Napren-E, Naproxen Evolan
  • Poland · 4flex Puregel, Aleve
  • Portugal · Actronadol, Ilgesin
  • Romania · Mobilat Pro, Naldorex
  • Sweden · Ipaflex, Naprocur
  • Slovenia · Nalgesin, Nalgesin Forte
  • Slovakia · Emoxen Gél, Nalgesin Forte

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of AIFA (Italy). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/ddcabdba-9759-4af6-9c08-8edc4be5135b
GET /v1/drugs/ddcabdba-9759-4af6-9c08-8edc4be5135b?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "pack": "\"500 MG GRANULATO\" 30 BUSTINE",
  "source": "aifa",
  "currency": "EUR",
  "substance": "Naprossene",
  "reference_pack": "30 UNITA' 500 MG - USO ORALE",
  "public_price_eur": 4.78,
  "ssn_reference_price_eur": 7.97
}

See everything about naproxen.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.