United States· US:50090-5581_4548ea65-4102-4f51-864d-d9dfafd7c5ea

tacrolimus

A tacrolimus product containing tacrolimus, registered in United States by A-S Medication Solutions. The same ATC class is registered in 16 of our 19 countries.

ATC L04AD02Orange BookUS label

Checked against FDA National Drug Code directory (United States) on

Informational only — not a medical device.

SOURCE REGISTER · USFDA National Drug Code directory (Unite…normalisedtacrolimusATCL04AD02REGISTER NO.US:50090-5581_4548ea6…PACKS LISTED1CHECKEDSeptember 12, 2026

Where it is registered

Tacrolimus is registered in 16 of 19 countries.

Countries holding a registration under ATC L04AD02 (tacrolimus), each read from that country’s own register.

  • This record: United States, from FDA National Drug Code directory (United States)
  • 9 of them publish a price we can compare per daily dose

Tacrolimus · ATC L04AD02

16 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Germany
  • Icelandprice
  • Ireland
  • Italyprice
  • Japan
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
  • United Kingdom
  • United Statesprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of tacrolimus costs, country by country.

Normalised to the WHO defined daily dose (5 mg), the median price runs from $0.77 in United States to $15.16 in Switzerland — a ×20 gap.

  • United States: $0.77 per daily dose (median across products in the class)
  • Public list prices, converted to USD at the rate date shown
  • US figures are pharmacy acquisition cost (CMS NADAC), not retail

Tacrolimus · price per daily dose (5 mg)

USD · FX 28 Sept 2026

  • CH Switzerland$15.16
  • IT Italy$8.99
  • ES Spain$6.82
  • US United States$0.77 (acquisition cost)
Median listed price per WHO defined daily dose, in each market that publishes a price. US = pharmacy acquisition cost (CMS NADAC), not a retail price. Open the full comparison

The record

At a glance

FDA National Drug Code directory (United States)
Active substance
tacrolimus
Manufacturer
A-S Medication Solutions
Country
United States (US)
ATC code
L04AD02
ATC class
Tacrolimus
Defined daily dose
5 mg, O
Reimbursed
Not published by this register
Source register
FDA National Drug Code directory (United States)
Last checked
September 12, 2026

Packs & prices · 1

  • ndc11
    5009055810
    90 CAPSULE in 1 BOTTLE (50090-5581-0)

Regulatory notes

UNII (FDA substance ID)
WM0HAQ4WNM
TACROLIMUS
RxCUI 484288
Orange Book
A206662
ABABAB
DailyMed SPL labels
1 version tracked

Interactions

1075 interactions on record for tacrolimus.

Graded by severity as the source publishes them — 238 severe. Severity grades are free for everyone; mechanism and management come with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan

Tacrolimus · interactions on record

1075 records

  • 238 severe
  • 543 moderate
  • 18 minor
  • 217 info

Most severe, free to view

  • ClotrimazoleA01AB18severe
  • OmeprazoleA02BC01severe
  • LansoprazoleA02BC03severe
  • EsomeprazoleA02BC05severe

59 more interactions with mechanism and management, from a commercially licensed source.

Sign in to check
  • Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.
Mechanism and what to do, in the interaction check
Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Tacrolimus in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All tacrolimus products

Authorised across Europe · EMA

The same active substance is authorised in 31 EEA countries. Names it is sold under:

  • Austria · Adport, Dailiport
  • Belgium · Adoport, Dailiport
  • Bulgaria · Програф
  • Cyprus · Prograf, Tacrolimus Accord
  • Czechia · Dailiport, Gecrol
  • Germany · Crilomus, Dailiport
  • Denmark · Adport, Dailiport
  • Estonia · Dailiport, Lebsanan
  • Spain · Adoport, Cellmune
  • Finland · Adport, Adport,
  • France · Adoport, Conferoport
  • United Kingdom (Northern Ireland) · Adoport, Ascezo
  • Greece · Atodrit-Dermo, Eczatope Derm
  • Croatia · Atezyrix, Dermitopic
  • Hungary · Prograf, Tacrolimus Stada
  • Ireland · Prograf, Tacrolimus Accord
  • Iceland · Advagraf, Dailiport
  • Italy · Adoport, Carelimus
  • Liechtenstein · Advagraf, Envarsus
  • Lithuania · Dailiport, Lebsanan
  • Luxembourg · Prograft, Sumilor
  • Latvia · Dailiport, Lebsanan
  • Malta · Prograf
  • Netherlands · Adport, Conferoport
  • Norway · Adport, Advagraf
  • Poland · Cidimus, Dailiport
  • Portugal · Adoport, Dermitopic
  • Romania · Prograf, Tacrolimus Sandoz
  • Sweden · Adport, Adport,
  • Slovenia · Adoport, Dailiport
  • Slovakia · Atezyrix, Dailiport

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/dd3f7683-0dbc-4897-a053-a57c288be284
GET /v1/drugs/dd3f7683-0dbc-4897-a053-a57c288be284?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "unii": {
    "unii": "WM0HAQ4WNM",
    "rxcui": "484288",
    "inchikey": "NWJQLQGQZSIBAF-MLAUYUEBSA-N",
    "display_name": "TACROLIMUS",
    "substance_type": "chemical",
    "ingredient_type": "INGREDIENT SUBSTANCE"
  },
  "route": "ORAL",
  "livertox": {
    "summary": null,
    "livertox_id": null,
    "hepatotoxicity_score": 3
  },
  "spl_meta": {
    "0a557ca9-b1a1-cf8f-a317-e4d8d4d6e60f": {
      "match": "brand_token",
      "title": "TACROLIMUS (TACROLIMUS) CAPSULE [BIOCON PHARMA INC.]",
      "spl_version": "12",
      "published_date": "2026-05-26"
    }
  },
  "productid": "50090-5581_4548ea65-4102-4f51-864d-d9dfafd7c5ea",
  "productndc": "50090-5581",
  "dosage_form": "CAPSULE",
  "orange_book": {
    "appl_no": "206662",
    "products": [
      {
        "rs": false,
        "rld": false,
        "te_code": "AB",
        "strength": "EQ 0.5MG BASE",
        "product_no": "001",
        "approval_date": "Nov 10, 2020"
      },
      {
        "rs": false,
        "rld": false,
        "te_code": "AB",
        "strength": "EQ 1MG BASE",
        "product_no": "002",
        "approval_date": "Nov 10, 2020"
      },
      {
        "rs": false,
        "rld": false,
        "te_code": "AB",
        "strength": "EQ 5MG BASE",
        "product_no": "003",
        "approval_date": "Nov 10, 2020"
      }
    ],
    "appl_type": "A"
  },
  "dea_schedule": null,
  "product_type": "HUMAN PRESCRIPTION DRUG",
  "substance_name": "TACROLIMUS",
  "proprietary_name": "tacrolimus",
  "active_ingred_unit": "mg/1",
  "application_number": "ANDA206662",
  "marketing_category": "ANDA",
  "nonproprietary_name": "tacrolimus",
  "start_marketing_date": "20201110",
  "active_numerator_strength": "1"
}

See everything about tacrolimus.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.