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Ireland· IE-PA-PA1824/019/001

Combigan 2 mg/ml + 5 mg/ml eye drops, solution

A timolol, kombinationen product containing brimonidine tartrate + timolol maleate, registered in Ireland by AbbVie Limited. The same ATC class is registered in 12 of our 19 countries.

ATC S01ED51

Checked against HPRA (Ireland) on

Informational only — not a medical device.

SOURCE REGISTER · IEHPRA (Ireland)normalisedCombigan 2 mg/ml + 5 mg/ml eye drops,…ATCS01ED51REGISTER NO.IE-PA-PA1824/019/001PACKS LISTED1CHECKEDSeptember 28, 2026
Compare price across countriesPer daily dose · free accountAsk the assistant about brimonidine tartrate + timolol maleateAnswers with sources · free accountCheck interactionsSeverity free · mechanism on Growth

Where it is registered

Timolol, kombinationen is registered in 12 of 19 countries.

Countries holding a registration under ATC S01ED51 (timolol, kombinationen), each read from that country’s own register.

  • This record: Ireland, from HPRA (Ireland)
  • 8 of them publish a price we can compare per daily dose
Search timolol, kombinationen products by name

Timolol, kombinationen · ATC S01ED51

12 / 19 countries

  • Belgiumprice
  • Canada
  • Czechiaprice
  • Denmark
  • Finlandprice
  • Icelandprice
  • Ireland
  • Italyprice
  • Netherlands
  • Norwayprice
  • Polandprice
  • Switzerlandprice
Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

The record

At a glance

HPRA (Ireland)
Active substance
Brimonidine tartrate + Timolol Maleate
Manufacturer
AbbVie Limited
Country
Ireland (IE)
ATC code
S01ED51
ATC class
Timolol, Kombinationen
Reimbursed
Not published by this register
Source register
HPRA (Ireland)
Last checked
September 28, 2026

Packs & prices · 1

  • ie_pa_number
    PA1824/019/001

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

1 interaction on record for timolol, kombinationen.

Mechanism, severity and management for each pair, from a commercially licensed source — included with Growth.

  • Severity for every pair — free, no plan needed
  • The source, licence and sync date on every record
  • Mechanism and what to do for each pair — Growth plan
Check timolol, kombinationen against other medicinesHow interaction checks work

Timolol, kombinationen · interactions on record

1 record

1 more interaction with mechanism and management, from a commercially licensed source.

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Mechanism and what to do, in the interaction check
Interaction register. Grades as the source publishes them.

Same medicine, other countries

Timolol, kombinationen in 13 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All timolol, kombinationen products

Authorised across Europe · EMA

The same active substance is authorised in 27 EEA countries. Names it is sold under:

  • Austria · Bazofex, Brimosine Duo
  • Belgium · Combigan
  • Bulgaria · Brimosine Duo, Бримонидин/Тимолол Ромфарм
  • Cyprus · Brimonidine Tartrate / Timolol Kleva
  • Czechia · Brimonidin/Timolol Olikla, Combigan
  • Germany · Brimonidin/Timolol Pharmathen, Brimosine Duo
  • Denmark · Brimonidin/Timolol Stada, Brimonidintartrat/Timolol Doc Generici
  • Estonia · Combigan
  • Spain · Combigan, Duabrima
  • Finland · Combigan
  • France · Brimonidine /Timolol Viatris, Brimonidine/Timolol Biogaran
  • United Kingdom (Northern Ireland) · Abrivis Duo, Brimonidine Tartrate /Timolol Generics [uk]
  • Greece · Brimontal-Co, Combigan
  • Croatia · Bericomb, Combigan
  • Hungary · Combigan
  • Italy · Brimocomb, Brimonidina E Timololo Mylan
  • Lithuania · Combigan
  • Luxembourg · Combigan
  • Latvia · Combigan
  • Netherlands · Brimonidinetartraat/Timolol Blumont, Combigan
  • Norway · Combigan
  • Poland · Combigan
  • Portugal · Bericomb, Bglau Duo
  • Romania · Briminodină/Timolol Rompharm, Combigan
  • Sweden · Combigan
  • Slovenia · Combigan
  • Slovakia · Bericomb, Brimonidin/Timolol Olikla

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of HPRA (Ireland). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload
GET /v1/drugs/db89c3d4-8d40-45df-81e9-503fc09449f7
GET /v1/drugs/db89c3d4-8d40-45df-81e9-503fc09449f7?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Eye drops, solution",
  "routes": [
    "Ocular use"
  ],
  "source": "hpra",
  "atc_all": [
    "S01ED",
    "S01ED51"
  ],
  "strength": null,
  "pa_number": "PA1824/019/001",
  "substances": [
    "Brimonidine tartrate",
    "Timolol Maleate"
  ],
  "legal_basis": "Fixed combination application (Article 10b of Directive No 2001/83/EC)",
  "market_info": "Not marketed",
  "authorised_at": "22/12/2005",
  "dispensing_status": "Product subject to prescription which may be renewed (B)",
  "registration_status": "AU",
  "supply_legal_status": "Supply through pharmacies only",
  "interchangeable_code": null
}
API referenceMCP serverPlans

See everything about timolol, kombinationen.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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