United States· US:0065-4147_889225d1-6257-4b32-b9cc-5f9c459c994a
SIMBRINZA
A medicinal product containing brinzolamide; brimonidine tartrate, registered in United States by Alcon Laboratories, Inc..
Checked against FDA National Drug Code directory (United States) on
Informational only — not a medical device.
The record
At a glance
FDA National Drug Code directory (United States)- Active substance
- BRINZOLAMIDE; BRIMONIDINE TARTRATE
- Manufacturer
- Alcon Laboratories, Inc.
- Country
- United States (US)
- ATC code
- —
- Reimbursed
- Not published by this register
- Source register
- FDA National Drug Code directory (United States)
- Last checked
- September 27, 2026
Packs & prices · 4
- ndc1100654147251 BOTTLE, DROPPER in 1 CARTON (0065-4147-25) / 2.5 mL in 1 BOTTLE, DROPPER
- ndc1100654147271 BOTTLE, DROPPER in 1 CARTON (0065-4147-27) / 8 mL in 1 BOTTLE, DROPPER
- ndc110065-4147-25
- ndc110065-4147-27
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Same medicine, other countries
Brinzolamide; brimonidine tartrate in 14 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- SwedenBrinzolamid/Brimonidin Medical Valley 10 mg/ml + 2 mg/ml Ögondroppar, suspensionMedical Valley Invest AB
- GermanyBrinzolamid/Brimonidin AlAliud Pharma Gmbh
- United KingdomBrinzolamide 10mg/ml / Brimonidine 2mg/ml eye dropsAspire Pharma Ltd
- CzechiaBRIDUOPHTAVIATRIS LIMITED, Dublin
- NetherlandsBriduophta 10 mg/ml + 2 mg/ml, oogdruppels, suspensieViatris Limited
- SpainBRINZOLAMIDA/BRIMONIDINA STADA 10 MG/ML + 2 MG/ML COLIRIO EN SUSPENSIONLaboratorio Stada S.L.
- NorwayBrinzolamid/Brimonidin Medical ValleyMedical Valley Invest AB
- FinlandBrinzolamide/Brimonidine STADASTADA Arzneimittel AG
Authorised across Europe · EMA
The same active substance is authorised in 15 EEA countries. Names it is sold under:
- Czechia · Briduophta
- Germany · Brinzolamid/Brimonidin Al, Brinzolamid/Brimonidin Axiromed
- Denmark · Brinzolamid/Brimonidin "medical Valley", Brinzolamide/Brimonidine Stada
- Spain · Brinzolamida/Brimonidina Stada, Brinzolamida/Brimonidina Zentiva
- Finland · Brinzolamide/Brimonidine Stada
- France · Brinzolamide/Brimonidine, Brinzolamide/Brimonidine Pharmathen
- United Kingdom (Northern Ireland) · Brinzolamide + Brimonidine Blumont Pharma, Brinzolamide/Brimonidine Tartrate Aspire Pharma
- Greece · Leznoda
- Iceland · Brinzolamide/Brimonidine Stada, Simbrinza
- Liechtenstein · Simbrinza
- Netherlands · Briduophta, Brinzolamide/Brimonidine Blumont
- Norway · Brinzolamid/Brimonidin Medical Valley, Simbrinza
- Portugal · Fixobim
- Sweden · Brinzolamid/Brimonidin Medical Valley, Brinzolamid/Brimonidin Zentiva
- Slovakia · Briduophta
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of FDA National Drug Code directory (United States). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/da8ac047-7a38-4e88-bbbf-1fd218444ef1 GET /v1/drugs/da8ac047-7a38-4e88-bbbf-1fd218444ef1?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"route": "OPHTHALMIC",
"source": "ndc",
"strength": "10; 2",
"substance": "BRINZOLAMIDE; BRIMONIDINE TARTRATE",
"productndc": "0065-4147",
"dosage_form": "SUSPENSION/ DROPS",
"dea_schedule": null,
"strength_unit": "mg/mL; mg/mL",
"application_number": "NDA204251",
"marketing_category": "NDA"
}See everything about brinzolamide; brimonidine tartrate.
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.