France· FR:66845664
LODOZ 2,5 mg/6,25 mg, comprimé pelliculé
A medicinal product containing hydrochlorothiazide + bisoprolol (fumarate de), registered in France by MERCK SANTE, on the national reimbursement list.
Checked against Base de données publique des médicaments — BDPM (France) on
Informational only — not a medical device.
The record
At a glance
Base de données publique des médicaments — BDPM (France)- Active substance
- HYDROCHLOROTHIAZIDE + BISOPROLOL (FUMARATE DE)
- Manufacturer
- MERCK SANTE
- Country
- France (FR)
- ATC code
- —
- Reimbursed
- Yes
- Source register
- Base de données publique des médicaments — BDPM (France)
- Last checked
- September 12, 2026
Packs & prices · 2
2 priced- cip133400938696325plaquette(s) PVC aluminium de 30 comprimé(s)EUR 5.02
- cip133400938696615plaquette(s) PVC aluminium de 90 comprimé(s)EUR 14.17
Regulatory notes
No shortage, Orange Book or US label notes for this record.
Same medicine, other countries
Hydrochlorothiazide + bisoprolol (fumarate de) in 9 other countries
What each register calls a product with the same active substance — salts and hydrates count as the same.
- United Statesbisoprolol fumarate and hydrochlorothiazideUnichem Pharmaceuticals (USA), Inc.
- FinlandBiso Comp. Abz-PharmaAbZ-Pharma GmbH
- CzechiaCOMBISOPRO.MED.CS Praha a.s.
- SwitzerlandBilol comp
- GermanyBisohexal Plus 10/25Hexal Ag
- ItalyBISOPROLOLO E IDROCLOROTIAZIDE AUROBINDOAUROBINDO PHARMA ITALIA S.R.L.
- SpainBISOPROLOL/HIDROCLOROTIAZIDA AUROVITAS 10 MG/25 MG COMPRIMIDOS RECUBIERTOS CON PELICULA EFGAurovitas Spain, S.A.U.
- NorwayLodozMerck AB (1)
Authorised across Europe · EMA
The same active substance is authorised in 21 EEA countries. Names it is sold under:
- Austria · Bisoprolol-Hct Viatris, Bisostad Plus
- Belgium · Co-Bisoprolol, Co-Bisoprolol Eg
- Bulgaria · Бисоплюс Ал, Лодоз
- Czechia · Combiso, Lodoz
- Germany · Bisohexal Plus 10/25, Bisohexal Plus 5/12,5
- Denmark · Cardiospir Plus
- Spain · Bisoprolol/Hidroclorotiazida Aurovitas, Bisoprolol/Hidroclorotiazida Teva
- Finland · Bisoprolol Comp Ratiopharm, Emconcor Comp
- Greece · Theracor Plus
- Croatia · Lodoz
- Hungary · Concor Plus
- Italy · Bisoprololo E Idroclorotiazide Aurobindo, Bisoprololo E Idroclorotiazide Mylan Generics
- Luxembourg · Co-Bisoprolol, Concor 10 Plus
- Latvia · Lodoz
- Malta · Bisocombimyl
- Netherlands · Bisoprololfumaraat/Hydrochloorthiazide Cf, Bisoprololfumaraat/Hydrochloorthiazide Viatris
- Norway · Lodoz
- Portugal · Bisoprolol + Hidroclorotiazida Generis, Concor 10 Plus
- Romania · Lodoz
- Slovenia · Lodoz
- Slovakia · Bisomyl Combi, Lodoz
Source: European Medicines Agency, Article 57 product data.
Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of Base de données publique des médicaments — BDPM (France). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.
For developers
The same record over the API, and the raw payload
GET /v1/drugs/da41ec60-e9c5-4e3a-a09f-4bf147acb1fd GET /v1/drugs/da41ec60-e9c5-4e3a-a09f-4bf147acb1fd?format=fhir
Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.
{
"cis": "66845664",
"date_amm": "1998-01-20",
"type_amm": "Procédure de reconnaissance mutuelle",
"numero_ue": null,
"substance": "HYDROCHLOROTHIAZIDE + BISOPROLOL (FUMARATE DE)",
"statut_amm": "Autorisation active",
"statut_bdm": null,
"forme_pharmaceutique": "comprimé pelliculé",
"voies_administration": "orale",
"etat_commercialisation": "Commercialisée",
"surveillance_renforcee": "Non"
}See everything about hydrochlorothiazide + bisoprolol (fumarate de).
This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.