Netherlands· NL-90427cb667b5

Spiriva Respimat 2,5 microgram, oplossing voor inhalatie

A tiotropium bromide product containing tiotropiumbromide 1-water, registered in Netherlands by Euro Registratie Collectief B.V.. The same ATC class is registered in 13 of our 19 countries.

ATC R03BB04

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about tiotropiumbromide 1-waterAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Tiotropium bromide is registered in 13 of 19 countries.

Countries holding a registration under ATC R03BB04 (tiotropium bromide), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
8 of them publish a price we can compare per daily dose

Search tiotropium bromide products by name

Tiotropium bromide · ATC R03BB04

13 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Icelandprice
Ireland
Italyprice
Japan
Netherlands
Norwayprice
Polandprice
Switzerlandprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of tiotropium bromide costs, country by country.

Normalised to the WHO defined daily dose (5 mcg), so markets compare like for like.

2 markets with a comparable price for this class
Public list prices, converted to USD at the rate date shown

Open the full comparison — free account Drug prices for market access

Tiotropium bromide · price per daily dose (5 mcg)

USD · FX 28 Sept 2026

CH Switzerland$0.50
IT Italy$0.34

Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

CBG-MEB (Netherlands)

Active substance: TIOTROPIUMBROMIDE 1-WATER
Manufacturer: Euro Registratie Collectief B.V.
Country: Netherlands (NL)
ATC code: R03BB04
ATC class: Tiotropium bromide
Defined daily dose: 5 mcg, Inhal
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
109483//34382

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

510 interactions on record for tiotropium bromide.

Graded by severity as the source publishes them — 113 moderate. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check tiotropium bromide against other medicines How interaction checks work

Tiotropium bromide · interactions on record

510 records

113 moderate
2 minor
395 info

Most severe, free to view

DicycloverineA03AA07moderate
PropanthelineA03AB05moderate
MepenzolateA03AB12moderate
TrospiumA03AB20moderate

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Tiotropium bromide in 18 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All tiotropium bromide products

Authorised across Europe · EMA

The same active substance is authorised in 30 EEA countries. Names it is sold under:

Austria · Braltus, Spiriva
Belgium · Spiriva, Spiriva Respimat
Bulgaria · Бралтус, Плубром
Cyprus · Spiriva, Spiriva Respimat
Czechia · Gartior, Spiriva
Germany · Acopair, Braltus
Denmark · Braltus, Spiriva
Estonia · Spiriva Respimat
Spain · Braltus, Gregal
Finland · Spiriva, Spiriva Respimat
France · Spiriva, Spiriva Respimat
United Kingdom (Northern Ireland) · Abtio, Acopair
Greece · Spiriva, Spiriva Respimat
Croatia · Acopair, Braltus
Hungary · Braltus, Ontipria
Ireland · Braltus, Spiriva
Iceland · Braltus, Spiriva
Italy · Scinorus, Sirkava
Liechtenstein · Spiriva, Spiriva Respimat
Lithuania · Spiriva, Spiriva Respimat
Luxembourg · Spiriva, Spiriva Respimat
Latvia · Spiriva, Spiriva Respimat
Malta · Spiriva, Spiriva Respimat
Norway · Braltus, Spiriva
Poland · Braltus, Gartior
Portugal · Braltus, Brometo De Tiotrópio Stada
Romania · Dilochob, Gregal
Sweden · Braltus, Sirkava
Slovenia · Spiriva, Spiriva Respimat
Slovakia · Spiriva, Spiriva Respimat

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/d6499b18-d173-4da8-b361-cdfa20679697
GET /v1/drugs/d6499b18-d173-4da8-b361-cdfa20679697?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Inhalatieoplossing",
  "route": "Inhalatie",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h34382_smpc.pdf",
  "strength": null,
  "atc_label": "Tiotropium Bromide",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg109483",
  "excipients": [
    "BENZALKONIUMCHLORIDE",
    "DINATRIUMEDETAAT 2-WATER",
    "WATER, GEZUIVERD",
    "ZOUTZUUR (E 507)"
  ],
  "substances": [
    "TIOTROPIUMBROMIDE 1-WATER"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h109483.pdf",
  "authorised_at": "2011/04/11",
  "procedure_number": null,
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "109483//34382",
  "additional_monitoring": "N"
}

API reference MCP server Plans

See everything about tiotropium bromide.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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