THAM

{
  "unii": {
    "unii": "023C2WHX2V",
    "rxcui": "10865",
    "inchikey": "LENZDBCJOHFCAS-UHFFFAOYSA-N",
    "display_name": "TROMETHAMINE",
    "substance_type": "chemical",
    "ingredient_type": "INGREDIENT SUBSTANCE"
  },
  "route": "INTRAVENOUS",
  "spl_meta": {
    "4af52118-c12b-4ad5-30bb-959848357e8a": {
      "match": "brand_token",
      "title": "THAM (TROMETHAMINE) INJECTION, SOLUTION [HOSPIRA, INC.]",
      "spl_version": "21",
      "published_date": "2026-05-28"
    }
  },
  "productid": "0409-1593_66406bf4-d7c7-4e73-9675-defa737c3b75",
  "productndc": "0409-1593",
  "dosage_form": "INJECTION, SOLUTION",
  "orange_book": {
    "appl_no": "013025",
    "products": [
      {
        "rs": false,
        "rld": false,
        "te_code": null,
        "strength": "370MG/VIAL;1.75GM/VIAL;36GM/VIAL",
        "product_no": "001",
        "approval_date": "Approved Prior to Jan 1, 1982"
      },
      {
        "rs": true,
        "rld": true,
        "te_code": "AP",
        "strength": "18GM/500ML (3.6GM/100ML) **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**",
        "product_no": "002",
        "approval_date": "Approved Prior to Jan 1, 1982"
      }
    ],
    "appl_type": "N"
  },
  "dea_schedule": null,
  "product_type": "HUMAN PRESCRIPTION DRUG",
  "substance_name": "TROMETHAMINE",
  "proprietary_name": "THAM",
  "active_ingred_unit": "g/100mL",
  "application_number": "NDA013025",
  "marketing_category": "NDA",
  "nonproprietary_name": "TROMETHAMINE",
  "start_marketing_date": "20200624",
  "active_numerator_strength": "3.6"
}