Netherlands· NL-fbf64b11c95f

Bosentan Sandoz 62,5 mg, filmomhulde tabletten

A bosentan product containing bosentan 1-water, registered in Netherlands by Sandoz B.V.. The same ATC class is registered in 18 of our 19 countries.

ATC C02KX01

Checked against CBG-MEB (Netherlands) on September 29, 2026

Informational only — not a medical device.

Compare price across countriesPer daily dose · free account Ask the assistant about bosentan 1-waterAnswers with sources · free account Check interactionsSeverity free · mechanism on Growth

Where it is registered

Bosentan is registered in 18 of 19 countries.

Countries holding a registration under ATC C02KX01 (bosentan), each read from that country’s own register.

This record: Netherlands, from CBG-MEB (Netherlands)
11 of them publish a price we can compare per daily dose

Search bosentan products by name

Bosentan · ATC C02KX01

18 / 19 countries

Belgiumprice
Canada
Czechiaprice
Denmark
Finlandprice
Franceprice
Germany
Icelandprice
Ireland
Italyprice
Netherlands
Norwayprice
Polandprice
Spainprice
Sweden
Switzerlandprice
United Kingdom
United Statesprice

Blue: a registration under this ATC code. The ringed marker is this record’s country. Markets marked price publish a price we can compare per daily dose.

Price per daily dose

What a daily dose of bosentan costs, country by country.

Normalised to the WHO defined daily dose (0.25 g), the median price runs from $25.92 in Italy to $66.51 in Switzerland — a ×2.6 gap.

2 markets with a comparable price for this class
Public list prices, converted to USD at the rate date shown

Open the full comparison — free account Drug prices for market access

Bosentan · price per daily dose (0.25 g)

USD · FX 28 Sept 2026

CH Switzerland$66.51
IT Italy$25.92

Median listed price per WHO defined daily dose, in each market that publishes a price. Open the full comparison

The record

At a glance

CBG-MEB (Netherlands)

Active substance: BOSENTAN 1-WATER
Manufacturer: Sandoz B.V.
Country: Netherlands (NL)
ATC code: C02KX01
ATC class: Bosentan
Defined daily dose: 0.25 g, O
Reimbursed: Not published by this register
Source register: CBG-MEB (Netherlands)
Last checked: September 29, 2026

Packs & prices · 1

cbg_meb_id
117029

Regulatory notes

No shortage, Orange Book or US label notes for this record.

Interactions

355 interactions on record for bosentan.

Graded by severity as the source publishes them — 45 severe. Severity grades are free for everyone; mechanism and management come with Growth.

Severity for every pair — free, no plan needed
The source, licence and sync date on every record
Mechanism and what to do for each pair — Growth plan

Check bosentan against other medicines How interaction checks work

Bosentan · interactions on record

355 records

45 severe
227 moderate
7 minor
69 info

Most severe, free to view

GlibenclamideA10BB01severe
Levonorgestrel and ethinylestradiolG03AA07severe
Desogestrel and ethinylestradiolG03AA09severe
Drospirenone and ethinylestradiolG03AA12severe

7 more interactions with mechanism and management, from a commercially licensed source.

Interaction severity from DDInter 2.0 (Xiong G. et al., Nucleic Acids Res.), licensed CC BY-NC 4.0 — free for non-commercial use only; not covered by the Drug Database commercial licence.

Mechanism and what to do, in the interaction check

Source: DDInter 2.0 · synced 29 Sept 2026. Grades as the source publishes them.

Same medicine, other countries

Bosentan in 16 other countries

What each register calls a product with the same active substance — salts and hydrates count as the same.

All bosentan products

Authorised across Europe · EMA

The same active substance is authorised in 29 EEA countries. Names it is sold under:

Austria · Bosentan Accord, Bosentan Reddy
Belgium · Bosentan Accord, Bosentan Sandoz
Bulgaria · Bosentan Sdz, Бозентан Акорд
Cyprus · Bactoced, Bosentan Accord
Czechia · Bosentan Abdi, Bosentan Accord
Germany · Bosentan 1 A Pharma, Bosentan Accord
Denmark · Bosentan Accord, Bosentan Cipla
Estonia · Bosentan Accord, Bosentan Norameda
Spain · Bosentan Accordpharma, Bosentán Accordpharma
Finland · Bosentan Accord
France · Bosentan Accord, Bosentan Arrow
United Kingdom (Northern Ireland) · Bosentan Accord, Bosentan Generics [uk]
Greece · Bocleer, Klimurtan
Croatia · Bosentan Cipla, Bosentan Makpharm
Hungary · Bosentan Pharmascience
Ireland · Bosentan Accord, Bosentan Zentiva
Iceland · Stayveer, Tracleer
Italy · Bosentan Abdi, Bosentan Accord
Liechtenstein · Stayveer, Tracleer
Lithuania · Bosentan Accord, Bosentan Norameda
Latvia · Bosentan Accord, Bosentan Norameda
Malta · Bosentan Aurobindo
Norway · Bosentan Accord, Bosentan Cipla
Poland · Bopaho, Bosentan Accord
Portugal · Bosentano Accord, Bosentano Aurobindo
Romania · Bopaho, Bosentan Accord
Sweden · Bosentan Accord, Bosentan Sandoz
Slovenia · Bosentan Norameda
Slovakia · Bosentan Accord

Source: European Medicines Agency, Article 57 product data.

Sourced from a public register and reproduced with attribution. Drug Database is not affiliated with, endorsed by, or a partner of CBG-MEB (Netherlands). This is an informational data service and not a medical device — verify against the official source of record before any clinical decision.

For developers

The same record over the API, and the raw payload

GET /v1/drugs/d352b530-f3cf-46df-aac8-9017635b1127
GET /v1/drugs/d352b530-f3cf-46df-aac8-9017635b1127?format=fhir

Every response carries last_synced_at, so freshness is a field rather than a promise. Below is exactly what the ingestion wrote, before any presentation — the same JSON the API returns under payload.

{
  "form": "Filmomhulde tablet",
  "route": "Oraal gebruik",
  "soort": "RVG",
  "source": "cbg_meb",
  "smpc_url": "https://www.geneesmiddeleninformatiebank.nl/smpc/h117029_smpc_en.pdf",
  "strength": null,
  "atc_label": "Bosentan",
  "detail_url": "https://www.geneesmiddeleninformatiebank.nl/nl/rvg117029",
  "excipients": [
    "ETHYLCELLULOSE (E 462)",
    "GLYCEROLDIBEHENAAT",
    "GLYCEROLTRIACETAAT (E 1518)",
    "HYPROMELLOSE 2910 (3 - 15 mPa.s) (E 464)",
    "IJZEROXIDE GEEL (E 172)",
    "IJZEROXIDE ROOD  (E 172)",
    "IJZEROXIDE ZWART (E 172)",
    "MAGNESIUMSTEARAAT (E 470b)",
    "MAÏSZETMEEL",
    "NATRIUMZETMEELGLYCOLAAT",
    "POLOXAMEER 188",
    "POVIDON K 30 (E 1201)",
    "SILICIUMDIOXIDE (E 551)",
    "TALK (E 553b)",
    "TITAANDIOXIDE (E 171)",
    "ZETMEEL, GEPREGELATINEERD"
  ],
  "substances": [
    "BOSENTAN 1-WATER"
  ],
  "leaflet_url": "https://www.geneesmiddeleninformatiebank.nl/bijsluiters/h117029_piluk.pdf",
  "authorised_at": "2016/05/12",
  "procedure_number": "NL/H/3422/001",
  "dispensing_status": "Uitsluitend recept",
  "registration_number": "117029",
  "additional_monitoring": "N"
}

API reference MCP server Plans

See everything about bosentan.

This page is the registration. A free account adds the label text as the regulator wrote it, what it costs per daily dose across the markets that publish a price, a feed of what changes in the registers, and an assistant that answers with its sources. Interaction severity is free; mechanism and management are on the Growth plan. No card, nothing to install.

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